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Identification Of Small Molecule That Destroys Potentially Dangerous Cells May Improve Stem Cell Therapies

Date: Apr-25-2013
Pluripotent stem cells can turn, or differentiate, into any cell type in the body, such as nerve, muscle or bone, but inevitably some of these stem cells fail to differentiate and end up mixed in with their newly differentiated daughter cells. Because these remaining pluripotent stem cells can subsequently develop into unintended cell types - bone cells among blood, for instance - or form tumors known as teratomas, identifying and separating them from their differentiated progeny is of utmost importance in keeping stem cell-based therapeutics safe...

Adolescents Likely More Vulnerable To Use And Abuse Of New Designer Drug 'Bath Salts'

Date: Apr-25-2013
Use and abuse of "bath salts," a new group of designer drugs, have been increasing in recent years, particularly among teenagers. Poison control centers received over 2,000 calls last year for patients with delusions, hallucinations and paranoia following "bath salt" use...

Vitamin E May Alleviate Symptoms Of Liver Disease Brought On By Obesity

Date: Apr-25-2013
A potential new way to fight obesity-related illness has been uncovered, thanks to serendipitous research led by investigators at the Case Western Reserve University School of Medicine. The collaborators, from Case Western Reserve University, the Cleveland Clinic Foundation and Cornell University, discovered the essential nutrient vitamin E can alleviate symptoms of liver disease brought on by obesity...

Inflammation's Likely Role In The Development Of Parkinson's Disease

Date: Apr-25-2013
Parkinson's disease (PD) is a progressive degenerative disease affecting a person's ability to coordinate and control their muscle movement. What starts out as a tremor in a finger will eventually lead to difficulty in writing and speaking, and ultimately the inability to walk without assistance. Since the 1950s research has shown that people with Parkinson's have decreased levels of the chemical dopamine in their brains, which is involved in sending messages to the part of the brain that controls coordination and movement...

Diagnosis Of UTI In Older Women Not Confirmed In Urine Culture In Nearly Half Of Cases

Date: Apr-25-2013
Older adults represent an important and growing demographic in emergency departments (ED) across the country, with urinary tract infections (UTIs) being one of the leading causes for ED visits. In fact, UTIs, which can progress to serious health concerns, are the fourth most common diagnosis in women over age 65. But a new study at Rhode Island Hospital has found that many such women receive treatment for a UTI, but have no firm evidence of such an infection, resulting in the prescribing of unnecessary antibiotics...

Ovarian Cancer Study Results Could Translate Into A Minimally Invasive Early Detection Method

Date: Apr-25-2013
Pioneering biophotonics technology developed at Northwestern University is the first screening method to detect the early presence of ovarian cancer in humans by examining cells easily brushed from the neighboring cervix or uterus, not the ovaries themselves. A research team from Northwestern and NorthShore University HealthSystem (NorthShore) conducted an ovarian cancer clinical study at NorthShore...

Atrophy In Key Region Of Brain Associated With Multiple Sclerosis

Date: Apr-25-2013
Magnetic resonance imaging (MRI) measurements of atrophy in an important area of the brain are an accurate predictor of multiple sclerosis (MS), according to a new study published online in the journal Radiology. According to the researchers, these atrophy measurements offer an improvement over current methods for evaluating patients at risk for MS. MS develops as the body's immune system attacks and damages myelin, the protective layer of fatty tissue that surrounds nerve cells within the brain and spinal cord...

The Importance Of Bonding And Empathy In The Patient-Physician Relationship

Date: Apr-25-2013
In a small study of 39 primary care doctors and 208 of their patients, Johns Hopkins researchers have found that physicians built much less of an emotional rapport with their overweight and obese patients than with their patients of normal weight. Bonding and empathy are essential to the patient-physician relationship. When physicians express more empathy, studies have shown that patients are more likely to adhere to medical recommendations and respond to behavior-change counseling - all vital elements in helping overweight and obese patients lose weight and improve health...

Scientists Advance Understanding Of Human Brown Adipose Tissue And Grow New Cells

Date: Apr-25-2013
Joslin scientists report significant findings about the location, genetic expression and function of human brown adipose tissue (BAT) and the generation of new BAT cells. These findings, which appear in the April 2013 issue of Nature Medicine, may contribute to further study of BAT's role in human metabolism and developing treatments that use BAT to promote weight loss. Two types of adipose (fat) tissue - brown and white - are found in mammals...

Angiogenesis Inhibitors Originally Conceived For Cancer Could Hold Promise For Weight Loss

Date: Apr-25-2013
Researchers have long known that cancerous tumors grow collections of abnormal blood cells, the fuel that feeds this disease and keeps it growing. Now, new evidence in an animal model suggests that blood vessels in the fat tissue of obese individuals could provide the same purpose - and could provide the key to a new way for people to lose weight. When researchers Jian-Wei Gu, Kristina L...