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People With A Severe Unexplained Psychological Illness Have Abnormal Activity In The Brain
Date: Feb-26-2013Psychogenic diseases, formerly known as 'hysterical' illnesses, can have many severe symptoms such as painful cramps or paralysis but without any physical explanation. However, new research from the University of Cambridge and UCL (University College London) suggests that individuals with psychogenic disease, that is to say physical illness that stems from emotional or mental stresses, do have brains that function differently. The research was published in the journal Brain...
The Role Stress Plays In Chronic Pain
Date: Feb-26-2013For chronic pain sufferers, such as people who develop back pain after a car accident, avoiding the harmful effects of stress may be key to managing their condition. This is particularly important for people with a smaller-than-average hippocampus, as these individuals seem to be particularly vulnerable to stress. These are the findings of a study by Dr...
Analytical Trick Accelerates Protein Studies
Date: Feb-26-2013Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions. Proteins are essential building blocks of biology, used in muscle, brain, blood and hormones. If the genes are the blueprints, the proteins patterned on them are the hammers and tongs of life...
Ablynx And Spirogen Enter Into A Research Collaboration To Evaluate The Potential Of Novel Toxin-Nanobody Drug Conjugates In Cancer
Date: Feb-26-2013Ablynx [Euronext Brussels: ABLX] and Spirogen Ltd. announce a research collaboration to evaluate the potential of a novel anti-cancer drug conjugate combining Spirogen's proprietary cytotoxic drugs, pyrrolobenzodiazepines (PBD), and associated linker technology, with Nanobodies® generated using Ablynx's proprietary technology platform. Under the terms of the collaboration, Ablynx will provide access to novel Nanobodies against a specific, undisclosed cancer target and Spirogen will provide access to its proprietary cytotoxic warheads (PBDs) and conjugation technologies...
Unique Brain Areas Related To Specific Human Cognitive Abilities
Date: Feb-26-2013Our ancestors' evolutionarily split from those of rhesus monkeys about 25 million years ago. Since then, brain areas have been added, have disappeared or have changed in function. This raises the question, 'Has evolution given humans unique brain structures?'. Scientists have entertained the idea before but conclusive evidence was lacking. By combining different research methods, we now have a first piece of evidence that could prove that humans have unique cortical brain networks...
The Case Of The Missing Heritability Cracked By Genomic Detectives
Date: Feb-26-2013Despite years of research, the genetic factors behind many human diseases and characteristics remain unknown. The inability to find the complete genetic causes of family traits such as height or the risk of type 2 diabetes has been called the "missing heritability" problem. A new study* by Princeton University researchers, however, suggests that missing heritability may not be missing after all - at least not in yeast cells, which the researchers used as a model for studying the problem...
Increased Risk Of Miscarriages Due To Rocket Attacks In Israel
Date: Feb-26-2013Rocket attacks in Sderot, Israel significantly increase the likelihood of miscarriages, according to a new study by Ben-Gurion University of the Negev (BGU) researchers. The study, published in the January issue of Psychosomatic Medicine Journal of Bio-behavioral Medicine, compared 1,341 pregnancies of women (exposed group) who resided in Sderot, an area exposed to frequent rocket fire, with 2,143 pregnancies of women who lived in Kiryat Gat (unexposed group), which is out of range of missiles...
Wide-Ranging Implications In Self-Assembly Of Small Molecules
Date: Feb-26-2013Sometimes the best discoveries come by accident. A team of researchers at Washington University in St. Louis, headed by Srikanth Singamaneni, PhD, assistant professor of mechanical engineering & materials science, unexpectedly found the mechanism by which tiny single molecules spontaneously grow into centimeter-long microtubes by leaving a dish for a different experiment in the refrigerator...
In Metastatic Lung Cancer, Local Therapy Followed By Treatment With EGFR TKI Is Well Tolerated
Date: Feb-26-2013Local therapy is not commonly utilized in metastatic lung cancer. Researchers at Memorial Sloan-Kettering Cancer Center investigated the efficacy of local therapy with continued EGFR TKI therapy specifically in patients with acquired resistance to EGFR TKIs...
Stem Cell Transplants, Chemotherapy Likely To Improve Following Discovery That Distinct Niches In Bone Marrow Nurture Blood Stem Cells
Date: Feb-26-2013In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells. Stem cells in the blood are the precursors to infection-fighting white blood cells and oxygen-carrying red blood cells. The research, by a team at Washington University School of Medicine in St. Louis, is reported in the advance online edition of Nature The new findings, in mice, suggest that it may be possible to therapeutically target support cells in a particular niche...
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