Targovax AS Announces First Patient Included In Phase I/II Clinical Study With The Therapeutic Cancer Vaccine TG01 In Operable Pancreatic Cancer

Date: Feb-04-2013Approval from the Norwegian Medicines Agency (NOMA) to start clinical phase I/II study
in Norway was received in November, and first patient was recruited in January.

18-24 patients will be included in the clinical Phase I/II study. Results from the
Phase I part are expected in first half of 2013.

Principal investigator and oncologist Svein Dueland states: "It is exciting that we
now recruit patients for this study, which originates from collaboration between Oslo
University Hospital and Norsk Hydro. Participation in clinical trials is an important part
of the treatment we can offer cancer patients."

Hanne Mette D Kristensen, CEO, says: "We are proud that Targovax now has its first
drug in clinical Phase I/II, only two years after the company's inception. The study will
run at the Radium Hospital at Oslo University Hospital, international pioneers in
development of immunotherapy and cancer vaccines. TG01 has already shown promising results
in patients. If these results are confirmed by systematic studies, TG01 may mean the first
real change for pancreatic cancer patients."

Targovax is owned by The Radium Hospital Research Foundation, Birk Venture and RO
Invest, inventors and management. The company has received grant from Innovation Norway
for running the clinical Phase I/II trial in collaboration with OUS, The Radium Hospital.

Targovax

Targovax is a cancer biotech-company started in October 2010. The TG01 cancer vaccine
is therapeutic; it is given as treatment to patients who already have cancer to prevent
recurrence, and educates the body's immune system to recognize and kill cancer cells.

Approximately 80-90% of pancreatic cancers have RAS mutations. Cancers with RAS
mutations have proved to be difficult to treat with current treatment, and there is a
significant unmet medical need.

A follow-up review of clinical trials from the end of the 90'es indicates increased
survival for patients treated with TG01. Some of these patients are still alive more than
ten years later. This is promising within a disease with very poor prognosis.

TG01 has received Orphan Drug Status for pancreatic cancer in EU and USA. Targovax
owns patents and the documentation from earlier development of TG01.

Courtesy: Medical News Today Note: Any medical information available in this news section is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional.