A Higher Strength Of Cholesterol-Lowering Drugs Did Not Increase The Risk Of Kidney Injury After Heart Attack
Date: Jun-21-2013A Higher Strength Of Cholesterol-Lowering Drugs Did Not Increase The Risk Of Kidney Injury After Heart Attack
Main Category: Statins
Also Included In: Cholesterol
Article Date: 21 Jun 2013 - 1:00 PDT
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A Higher Strength Of Cholesterol-Lowering Drugs Did Not Increase The Risk Of Kidney Injury After Heart Attack
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A higher strength of cholesterol-lowering drugs, or statins, did not increase the risk of kidney injury among heart attack survivors, according to preliminary research presented at the American Heart Association's Emerging Science Series Webinar.*
Statins have been shown to reduce the risk of a first or recurrent heart attack, but recent observational studies suggest that high doses may be linked to a higher incidence of kidney injury.
In this study, researchers analyzed data from two large clinical trials in which survivors were randomly assigned to receive either high- or low-dose statins. Higher strenght statins did not increase the risk of hospitalizations with kidney injury when compared to low-dose statins. In addition, concentrations of a blood protein, called creatinine, which reflects kidney function were comparable between the two groups during follow-up.
"These findings provide important reassurance to clinicians that the use of some high-potency statins will not increase the risk of kidney injury," said Amy Sarma, M.D., M.H.S., the study's lead author and a resident physician in internal medicine at Brigham and Women's Hospital in Boston, Mass.
Courtesy: Medical News Today
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