Nerve regeneration of skin pathological scars promoted by mechanical tension

Date: Jul-26-2013Scars are prone to appear at high tension parts, such as the sternum, shoulder and back, which are serious clinical problems.

Surgeons reduce scar formation through Z, W, V-Y flap variation and reduced blade tension, but its specific mechanism is still not very clear.

Hu Xiao and colleagues from Shandong Provincial Hospital Affiliated to Shandong University verified that mechanical tension contributed to the formation of a hyperplastic scar in the back skin of rats, in conjunction with increases in both nerve density and nerve growth factor expression in the scar tissue.

These experimental findings indicate that the cutaneous nervous system plays a role in hypertrophic scar formation caused by mechanical tension, which have been published in Neural Regeneration Research (Vol. 8, No. 17, 2013).

Courtesy: Medical News Today Note: Any medical information available in this news section is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional.