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For assisted reproduction, 2 Y genes can replace the entire Y chromosome in mice

Date: Nov-25-2013
The Y chromosome is a symbol of maleness, present only in males and encoding genes important for male reproduction. But live mouse offspring can be generated with assisted reproduction using germ cells from males with the Y chromosome contribution limited to only two genes: the testis determinant factor Sry and the spermatogonial proliferation factor Eif2s3y."Does this mean that the Y chromosome (or most of it) is no longer needed? Yes, given our current technological advances in assisted reproductive technologies," said Monika A.

Ibuprofen may prevent marijuana-induced memory problems

Date: Nov-25-2013
In addition to being used as a recreational drug, marijuana has been used for centuries to treat a variety of conditions, from chronic pain to epilepsy. However, its medical value is greatly limited by debilitating side effects. A study published by Cell Press in the journal Cell has revealed the molecular pathways responsible for marijuana-induced learning and memory problems. The findings suggest that preventing these side effects could be as easy as taking an over-the-counter painkiller.

Gene identified that regulates body weight in humans and mice

Date: Nov-25-2013
Research has pointed to the importance of genetic factors in human obesity and has shown that heritability plays a role in 40% to 90% of cases. Now investigators reporting online in The American Journal of Human Genetics, published by Cell Press, have found that loss of a particular gene's function in humans and mice causes morbid obesity. The study of a morbidly obese family provides new insights into the pathways that control body weight and nutritional status, and the results could be useful for designing therapies for obesity and malnutrition.

Babies born with the essential ingredients for body perception

Date: Nov-25-2013
The ability to differentiate your own body from others is a fundamental skill, critical for humans' ability to interact with their environments and the people in them. Now, researchers reporting in Current Biology, a Cell Press publication, provide some of the first evidence that newborn babies enter the world with the essential mechanisms for this kind of body awareness already in place.In addition to this insight into normal human development, the researchers stress the importance of the new findings for understanding atypical development, too.

Babies born with the essential ingredients for body perception

Date: Nov-25-2013
The ability to differentiate your own body from others is a fundamental skill, critical for humans' ability to interact with their environments and the people in them. Now, researchers reporting in Current Biology, a Cell Press publication, provide some of the first evidence that newborn babies enter the world with the essential mechanisms for this kind of body awareness already in place.In addition to this insight into normal human development, the researchers stress the importance of the new findings for understanding atypical development, too.

Together, flu and fungus-fighting drug could be life threatening

Date: Nov-25-2013
Mice given a drug commonly used in patients to fight systemic fungal infections more often succumb to what would otherwise be a mild case of the flu. The evidence reported in the Cell Press journal Cell Reports shows that the drug called Amphotericin B, which has an estimated $330 million in sales around the world each year, can render a protein important for antiviral defense ineffective in both cells and mice.

Together, flu and fungus-fighting drug could be life threatening

Date: Nov-25-2013
Mice given a drug commonly used in patients to fight systemic fungal infections more often succumb to what would otherwise be a mild case of the flu. The evidence reported in the Cell Press journal Cell Reports shows that the drug called Amphotericin B, which has an estimated $330 million in sales around the world each year, can render a protein important for antiviral defense ineffective in both cells and mice.

Ibuprofen may prevent marijuana-induced memory problems

Date: Nov-25-2013
In addition to being used as a recreational drug, marijuana has been used for centuries to treat a variety of conditions, from chronic pain to epilepsy. However, its medical value is greatly limited by debilitating side effects. A study published by Cell Press in the journal Cell has revealed the molecular pathways responsible for marijuana-induced learning and memory problems. The findings suggest that preventing these side effects could be as easy as taking an over-the-counter painkiller.

New computer model 'can accurately predict epileptic seizures'

Date: Nov-25-2013
Researchers have created a "computational model" which can more accurately predict when an epileptic patient will experience their next seizure. This is according to a study published in IEEE Transactions on Knowledge and Data Engineering.According to the Centers for Disease Control and Prevention (CDC), around 2.3 million US adults and 467,711 children suffer from epilepsy - one of the most common neurological disorders caused by temporary disturbances to the nerve cells in the brain.

Helping young people communicate clearly with their partners about parenting and HIV

Date: Nov-25-2013
A team from Royal Holloway University and St. Mary's Hospital, London, interviewed young people aged 18-23 who had transmitted HIV from their mothers - known as 'perinatally acquired HIV' (PAH). Previously most of these children would have died in childhood, but medication in the UK, means they are surviving into early adulthood.Researchers found that all of the participants wanted to become parents, but they were concerned about having to tell their children that they were HIV positive in the future and some were worried about transmitting HIV to their child.