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Changes to the ABPI Code of Practice ensures greater transparency on payments to healthcare professionals, UK
Date: Nov-12-2013ABPI member companies have agreed changes to amend the ABPI Code of Practice for the Pharmaceutical Industry to include greater transparency on payments made to healthcare professionals and healthcare organisations.1 Stephen Whitehead, Chief Executive of the ABPI, said: "For too long the industry has suffered from a common misunderstanding around the nature of its relationship with healthcare professionals...
Being overweight or obese are risk factors for heart disease regardless of metabolic syndrome
Date: Nov-12-2013Being overweight or obese are risk factors for myocardial infarction (heart attack) and ischemic heart disease (IHD) regardless of whether individuals also have the cluster of cardiovascular risk factors known as metabolic syndrome, which includes high blood pressure, high cholesterol and high blood sugar, according to a study published by JAMA Internal Medicine, a JAMA Network publication. Being overweight or obese likely causes MI and IHD but whether co-existing metabolic syndrome is necessary for the conditions to develop is unknown, according to the study authors. Børge G...
Women's pelvic pain often goes underreported, untreated
Date: Nov-12-2013Although many women experience pelvic pain in their late teens and early 20s, a new University of Florida Health study indicates that only a small fraction of these women report their symptoms to their doctors and seek treatment, leaving some health problems unresolved. Up to 72 percent of the women who responded to the survey reported experiencing pelvic pain in the past year, yet nearly three-quarters of them did not seek treatment from a physician...
Toxicology in the Twittersphere: More than just 140 characters
Date: Nov-12-2013A valuable role exists for the use of social media in medicine, new research has shown. Dr Joe-Anthony Rotella, in a letter to the editor in the latest Early View issue of Emergency Medicine Australasia, the journal of the Australasian College for Emergency Medicine, describes his investigation into the use of Twitter by individuals or organisations involved in clinical toxicology and poison control...
Problem-solving education reduces parental stress after child autism diagnosis
Date: Nov-12-2013A cognitive-behavioral intervention known as problem-solving education (PSE) may help reduce parental stress and depressive symptoms immediately after their child is diagnosed with autism spectrum disorder (ASD), according to a study by Emily Feinberg, CPNP, Sc.D., of Boston University School of Public Health, and colleagues. Mothers of children with ASD consistently report high levels of parental stress, depressive symptoms, and social isolation, according to the study background...
Some "healthy" vegetable oils may actually increase risk of heart disease
Date: Nov-12-2013Some vegetable oils that claim to be healthy may actually increase the risk of heart disease, and Health Canada should reconsider cholesterol-lowering claims on food labelling, states an analysis in CMAJ (Canadian Medical Association Journal). Replacing saturated animal fats with polyunsaturated vegetable oils has become common practice because they can reduce serum cholesterol levels and help prevent heart disease...
Breakthrough single-cell genome sequencing technique
Date: Nov-12-2013Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters. The study is published in the journal Nature Biotechnology. "Our preliminary data suggest that individual neurons from the same brain have different genetic compositions...
Un-junking junk DNA
Date: Nov-12-2013A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression. The study was published online in advance of print in the journal Nature Structural and Molecular Biology. "We uncovered a novel mechanism that allows proteins that direct pre-mRNA splicing - RNA-binding proteins - to induce a regulatory effect from greater distances than was thought possible," said first author Michael T...
The contribution of coding variants to psoriasis much smaller than thought
Date: Nov-12-2013Coding variants in immune disease-related genes play only a small part in the overall genetic risk for psoriasis, according to a new study led by Anhui Medical University and BGI. This conclusion is strongly supported by their investigation on the contribution of functional coding variants to psoriasis in 21,309 Chinese individuals. In such a large-scale investigation, researchers only discovered two independent low-frequency variants with moderate effect on disease risk. The latest study was published online in Nature Genetics. Psoriasis is a complex, chronic, lifelong skin disease...
Visual task learning aided by sleep
Date: Nov-12-2013As any indignant teacher would scold, students must be awake to learn. But what science is showing with increasing sophistication is how the brain uses sleep for learning as well. At the annual meeting of the Society for Neuroscience in San Diego, Brown University researchers discussed new research describing the neural mechanism by which the sleeping brain locks in learning of a visual task. The mounting evidence is that during sleep the brain employs neural oscillations - brainwaves - of particular frequencies to consolidate learning in specific brain regions...
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