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Bacterial disturbances in the gut may play a role in autoimmune attacks on the joints
Date: Nov-08-2013Researchers have linked a species of intestinal bacteria known as Prevotella copri to the onset of rheumatoid arthritis, the first demonstration in humans that the chronic inflammatory joint disease may be mediated in part by specific intestinal bacteria. The new findings by laboratory scientists and clinical researchers in rheumatology at NYU School of Medicine add to the growing evidence that the trillions of microbes in our body play an important role in regulating our health...
New research on little-understood brain disease hippocampal sclerosis (HS-AGING)
Date: Nov-08-2013As the population of older adults continues to grow, researchers at the University of Kentucky Sanders-Brown Center on Aging are engaged in work to understand the mechanisms of a variety of diseases that predominately affect those of advanced age. Three recent papers authored by Dr. Peter Nelson and others at the University of Kentucky Sanders-Brown Center on Aging, explore the neuropathology behind a little-understood brain disease, hippocampal sclerosis (known to scientists and clinicians as HS-AGING)...
Program helps reduce arthritis pain and improve mobility for Asian seniors
Date: Nov-08-2013Experts say it's never too late to reap the benefits of exercise, and a program offered in New York City senior centers is improving quality of life for many older adults. The exercise program, offered by Hospital for Special Surgery (HSS) in senior centers in New York City's Chinatown and Flushing, Queens communities, has helped decrease pain, improve mobility and enhance the overall health of many participants, according to a study by HSS...
New target for post-stroke depression
Date: Nov-08-2013MiRNAs likely play an important role in the occurrence and development of depression, and can be used as potential targets for treatment of depression. Studies have shown that miR-137 expression is downregulated in the brain from depression patients with suicidal behavior. Moreover, miR-137 expression is also downregulated in peripheral blood from stroke patients. However, it is not yet known if miRNAs are associated with post-stroke depression. To test this, Dr...
Researchers uncover clues to how existing heart drugs work
Date: Nov-08-2013Some of the most commonly prescribed drugs for the treatment of heart failure are beta-blockers and nitrates, which help to relax blood vessels and decrease the heart's workload. The drugs were thought to produce those effects through distinct molecular pathways, but according to a new study led by scientists at Temple University School of Medicine, both types of drugs may help the failing heart by counteracting the effects of an enzyme known as GRK2...
New treatment for heart attack likely following breakthrough by Temple researchers
Date: Nov-08-2013The stop and start of blood flow to the heart during and after a heart attack causes severe damage to heart cells, reducing their capacity to function and potentially causing their death. But a recent study led by researchers at Temple University School of Medicine suggests that it is possible to limit the extent of that damage using a drug. In experiments in mice that recapitulated a human clinical scenario, they discovered that inhibition of a heart protein called TNNI3K reduced damage from heart attack and protected the heart from further injury...
New study confirms health benefits of wild blueberries
Date: Nov-08-2013Wild blueberries are a rich source of phytochemicals called polyphenols, which have been reported by a growing number of studies to exert a wide array of protective health benefits. A new study by researchers at the University of Maine adds to this growing body of evidence. This new research, published in the journal Applied Physiology, Nutrition, and Metabolism, shows that regular long-term wild blueberry diets may help improve or prevent pathologies associated with the metabolic syndrome, including cardiovascular disease and diabetes...
New target for post-stroke depression
Date: Nov-08-2013MiRNAs likely play an important role in the occurrence and development of depression, and can be used as potential targets for treatment of depression. Studies have shown that miR-137 expression is downregulated in the brain from depression patients with suicidal behavior. Moreover, miR-137 expression is also downregulated in peripheral blood from stroke patients. However, it is not yet known if miRNAs are associated with post-stroke depression. To test this, Dr...
How multisensory stimuli influence multimodal behavior
Date: Nov-08-2013To survive, animals must explore their world to find the necessities of life. It's a complex task, requiring them to form them a mental map of their environment to navigate the safest and fastest routes to food and water. They also learn to anticipate when and where certain important events, such as finding a meal, will occur. Understanding the connection between these two fundamental behaviors, navigation and the anticipation of a reward, had long eluded scientists because it was not possible to simultaneously study both while an animal was moving...
Bacterial disturbances in the gut may play a role in autoimmune attacks on the joints
Date: Nov-08-2013Researchers have linked a species of intestinal bacteria known as Prevotella copri to the onset of rheumatoid arthritis, the first demonstration in humans that the chronic inflammatory joint disease may be mediated in part by specific intestinal bacteria. The new findings by laboratory scientists and clinical researchers in rheumatology at NYU School of Medicine add to the growing evidence that the trillions of microbes in our body play an important role in regulating our health...
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