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A variety of cancers destroyed by drug combination therapy
Date: Nov-07-2013Results from a recent preclinical study have shown that a new drug combination therapy being developed at Virginia Commonwealth University Massey Cancer Center effectively killed colon, liver, lung, kidney, breast and brain cancer cells while having little effect on noncancerous cells. The results lay the foundation for researchers to plan a future phase 1 clinical trial to test the safety of the therapy in a small group of patients...
Brain function abnormalities affect decision-making capacity of gambling addicts
Date: Nov-07-2013University of Granada researchers have analysed similarities and differences in psychological profile and brain function when comparing cocaine addicts and gambling addicts. The study reveals that gambling addicts present brain function abnormalities affecting their decision-making capacity. In two articles, recently published in Frontiers in Neuroscience, they confirm that cocaine has cumulative prejudicial effects on the functioning of areas of the brain (anterior cingulate and part of the prefrontal cortex) necessary for correct control of impulses...
New ligament in the human knee described by surgeons
Date: Nov-07-2013Two knee surgeons at University Hospitals Leuven have provided the first full anatomical description of a previously enigmatic ligament in the human knee. The ligament appears to play an important role in patients with anterior cruciate ligament (ACL) tears. Despite successful ACL repair surgery and rehabilitation, some patients with ACL-repaired knees continue to experience so-called 'pivot shift', or episodes where the knee 'gives way' during activity...
Pickled turnip from Japan - new superfood to prevent flu infection?
Date: Nov-07-2013Scientists have discovered that bacteria found in a traditional Japanese pickle can prevent flu. Could this be the next superfood? The research, which assesses the immune-boosting powers of Lactobacillus brevis from Suguki - a pickled turnip, popular in Japan - in mice that have been exposed to a flu virus, is published in the SfAM journal, Letters in Applied Microbiology. Lead researcher, Ms Naoko Waki of KAGOME CO., LTD. in Japan said: "Our results show that when a particular strain of Lactobacillus brevis is eaten by mice, it has protective effects against influenza virus infection...
Attitudes toward bisexuality affected by gender, race and sexuality
Date: Nov-07-2013Men who identify themselves as heterosexual are three times more likely to categorize bisexuality as "not a legitimate sexual orientation," an attitude that can encourage negative health outcomes in people who identify as bisexual, according to an analysis led by University of Pittsburgh Graduate School of Public Health researcher Mackey Friedman, Ph.D., M.P.H. The results of the survey, sponsored by the Indiana University Bloomington, were presented at the American Public Health Association's 141st Annual Meeting & Exposition in Boston...
Leishmaniasis treatment doses and side effects may be dramatically reduced by new discovery
Date: Nov-07-2013The Amphotericin B (AmB) is the main active ingredient in the most effective drug used to treat leishmaniasis, a disease which in the Western world mainly affects dogs, but in developing countries affects over 12 million people, with more than 70,000 deaths per year. The cost of treating humans with AmB surpasses $5,000 per patient, the treatment is extensive (2-hour sessions every day during 21 days), and the side effects are frequent and many times patients must be hospitalised...
Tissue cryopreservation for medical care moves forward
Date: Nov-07-2013Developing an efficient way to freeze and store living tissues could transform many aspects of medical care and research, but ice crystallization often occurs within cells during such cryopreservation procedures, leading to cell death. In the Biophysical Journal, a Cell Press publication, researchers report that they have gained new information about the processes that are responsible for promoting the freezing of cells within tissues. This knowledge may ultimately lead to novel approaches for preventing tissue injury during cryopreservation...
Statistical model teaches machines to detect breast cancer
Date: Nov-07-2013Software that can recognize patterns in data is commonly used by scientists and economics. Now, researchers in the US have applied similar algorithms to help them more accurately diagnose breast cancer. The researchers outline details in the International Journal of Medical Engineering and Informatics. Duo Zhou a biostatistician at pharmaceutical company Pfizer in New York and colleagues Dinesh Mital and Shankar Srinivasan of the University of Medicine and Dentistry of New Jersey, point out that data pattern recognition is widely used in machine-learning applications in science...
Prescription opioid availability and associated abuse
Date: Nov-07-2013Researchers at Indiana University-Purdue University Indianapolis say one way to gauge the extent of prescription opioid pain reliever abuse in any Indiana county is to count the number of health care providers, particularly dentists and pharmacists. In a study of opioid use and abuse, the researchers said they found that access to health care increases the availability of prescription opioids, which, in turn, is associated with higher rates of opioid abuse and associated consequences...
Musical training in childhood reaps neural benefits later in life
Date: Nov-07-2013Older adults who took music lessons as children but haven't actively played an instrument in decades have a faster brain response to a speech sound than individuals who never played an instrument, according to a study appearing in the Journal of Neuroscience. The finding suggests early musical training has a lasting, positive effect on how the brain processes sound. As people grow older, they often experience changes in the brain that compromise hearing. For instance, the brains of older adults show a slower response to fast-changing sounds, which is important for interpreting speech...
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