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Rampaging tumor cells
Date: Nov-07-2013Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. LMU researchers have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy. The protein c-MYC is referred to as a master regulator because it controls the activity of hundreds of genes, including many that drive cell growth and cell proliferation. Genetic changes that perturb its own regulation therefore have serious consequences for tissue homeostasis, and often result in cancer...
Preventing heart attacks and strokes using 'smarter' blood pressure guidelines
Date: Nov-07-2013A new way of using blood pressure-lowering medications could prevent more than a fourth of heart attacks and strokes - up to 180,000 a year - while using less medication overall, according to new research from the University of Michigan Health System and the VA Ann Arbor Healthcare System...
Annual car crash deaths in England and Wales have fallen 40% in 50 years
Date: Nov-07-2013The annual number of car crash deaths in England and Wales has plunged by 41% over the past 50 years, despite the increase in drivers on the road, reveals research published online in Emergency Medicine Journal. Nevertheless, these deaths may still be making an impact on the well recognised social class and gender differences in life expectancy seen in both countries, conclude the researchers. Around 1...
Modifying software design to reduce unnecessary lab tests, decrease patient costs
Date: Nov-07-2013When patients undergo diagnostic lab tests as part of the inpatient admission process, they may wonder why or how physicians choose particular tests. Increasingly, medical professionals are using electronic medical systems that provide lists of lab tests from which medical professionals can choose. Now, a University of Missouri researcher and her colleagues have studied how to modify these lists to ensure health professionals order relevant tests and omit unnecessary lab tests, which could result in better care and reduced costs for patients...
App accurately tracks physical activity no matter where you carry your phone
Date: Nov-07-2013Physical activity tracking apps on smart phones are a potentially important tool for doctors who want to collect data and create treatment or intervention plans to improve the health of patients who struggle with activity and movement -- such as those with Parkinson's disease. A new Northwestern Medicine® study has found a way to make these apps more accurate -- no matter where patients carry their phones. The study was recently published online in the Journal of Neuroscience Methods...
Unexpected backlash from transgender anti-discrimination measure
Date: Nov-07-2013When New York City moved in 2006 to make it easier for transgender people to revise the gender on their birth certificates, the proposal was widely expected to pass. But the anti-discrimination measure failed, in part because of public opposition to removing the requirement that individuals have genital surgery before claiming a different gender. "The backlash was intense," said Kristen Schilt, assistant professor of sociology at the University of Chicago. "There was such a fervor over taking the surgery requirement out, a sense of, 'Absolutely not. There's going to be chaos...
Good news or bad news: which do you want first?
Date: Nov-07-2013There's good news and there's bad news. Which do you want to hear first? That depends on whether you are the giver or receiver of bad news, and if the news-giver wants the receiver to act on the information, according to researchers at the University of California, Riverside. It's complicated. The process of giving or getting bad news is difficult for most people, particularly when news-givers feel unsure about how to proceed with the conversation, psychologists Angela M...
High survival rates in trial of new heart valve
Date: Nov-07-2013Loyola University Medical Center is the only Chicago hospital participating in a landmark clinical trial of an artificial aortic heart valve that does not require open heart surgery. First results from the trial were announced at the Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium in San Francisco. Results were positive, with high survival rates and low rates of stroke. "This is a major breakthrough," said Fred Leya, MD, co-principal investigator at the Loyola site. "Not only did patients live longer, but their quality of life improved substantially...
The effect of acupuncture on neuropathic pain
Date: Nov-07-2013Peripheral or central nerve injury often leads to neuropathic pain, a chronic condition that can manifest behaviorally as spontaneous pain, hyperalgesia and allodynia, and which also results in neurological dysfunction. Acupuncture has been used to treat neuropathic pain for a long time, but its mechanisms of action remain unknown...
Post-traumatic stress disorder and brain structure
Date: Nov-07-2013Wars, earthquakes, major traffic accidents, and terrorist attacks may bring about profound spiritual pains, and even cause extreme fear and helplessness for people that have experienced or witnessed these unusual threats or disasters. This persistent and constant mental disorder caused by psychological trauma is termed post-traumatic stress disorder (PTSD). Can brain structural damage alter as symptoms improve? As PTSD progresses, brain structure inevitably changes, however, no PTSD symptoms have been clearly described in previous PTSD imaging studies...
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