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Heart disease caused by reductive stress may be prevented by disrupting an antioxidant pathway
Date: Oct-15-2013University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy, a type of a heart failure in which the heart muscle grows abnormally thick. This new finding, published in the journal Cardiovascular Research, suggests that restoring the normal balance of reduction-oxidation chemical reactions in the body could prevent heart disease and other conditions caused by reductive stress...
Binge drinking during pregnancy linked to negative emotions
Date: Oct-15-2013Researchers in Norway found that negative affectivity is linked to light alcohol use and binge drinking during pregnancy. Pregnancy is often described as one of the happiest times in a woman's life, but according to The American Congress of Obstetricians and Gynecologists, between 14-23% of pregnant women will struggle with depression. Negative affectivity is the tendency to experience negative emotions, such as anxiety and depression. Women suffering from this often tend to have an unfavorable view of themselves and the world in general...
Why drivers text while driving despite the danger
Date: Oct-15-2013US research reveals that 4 out of 5 college student drivers have used their cell phones to send or receive text messages while driving despite the majority recognizing that the activity represents a risk. Garold Lantz and Sandra Loeb of the McGowan School of Business, at King's College, in Wilkes Barre, Pennsylvania, found that male drivers are more likely to engage in texting while driving but consider themselves more proficient drivers than others and so less likely to endanger themselves or others while doing so...
Moving closer to Epstein-Barr virus vaccine to prevent mono, some cancers
Date: Oct-15-2013Development of a vaccine against Epstein-Barr virus (EBV) has taken a step forward with the Canadian discovery of how EBV infection evades detection by the immune system. EBV causes infectious mononucleosis and cancers such as Hodgkin's lymphoma and nasopharyngeal carcinoma, which is the most common cancer in China, as well as opportunistic cancers in people with weakened immune systems. A member of the herpes virus family that remains in the body for life, the virus infects epithelial cells in the throat and immune cells called B cells...
Protein links exercise to brain health
Date: Oct-15-2013A protein that is increased by endurance exercise has been isolated and given to non-exercising mice, in which it turned on genes that promote brain health and encourage the growth of new nerves involved in learning and memory, report scientists from Dana-Farber Cancer Institute and Harvard Medical School. The findings, reported in the journal Cell Metabolism, help explain the well-known capacity of endurance exercise to improve cognitive function, particularly in older people...
The disproportionate effect of genes outside nucleus
Date: Oct-15-2013New research from the University of California, Davis, shows that the tiny proportion of a cell's DNA that is located outside the cell nucleus has a disproportionately large effect on a cell's metabolism. The work, with the model plant Arabidopsis, may have implications for future treatments for inherited diseases in humans. Plant and animal cells carry most of their genes on chromosomes in the nucleus, separated from the rest of the cell. However, they also contain a small number of genes in organelles that lie outside the nucleus...
Depression among kidney failure patients tackled via behavioral therapy during dialysis sessions
Date: Oct-15-2013Behavioral therapy provided chair-side to kidney failure patients while they're undergoing dialysis may help fight depression and improve patients' quality of life, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). Thanks to advances in medical technology, dialysis patients have the potential to live longer and healthier lives than ever before, but depression is a serious and prevalent problem among them...
Study reveals structure of 'gateway' compound in lethal food-borne toxin
Date: Oct-15-2013U.S. and German scientists have decoded a key molecular gateway for the toxin that causes botulism, pointing the way to treatments that can keep the food-borne poison out of the bloodstream. Study leaders Rongsheng Jin, associate professor of physiology & biophysics at UC Irvine, and Andreas Rummel of the Institute for Toxicology at Germany's Hannover Medical School created a three-dimensional crystal model of a complex protein compound in the botulinum neurotoxin. This compound binds to the inner lining of the small intestine and allows passage of the toxin into the bloodstream...
Researchers reveal Innovative concept for knee cartilage treatment
Date: Oct-15-2013Researchers have developed a material that can be used for the controlled release of a substance when subjected to cyclic mechanical loading. This work, carried out within the context of the National Research Programme "Smart Materials" (NRP 62), offers a potential treatment method for specific tissues such as knee cartilage. In order to regenerate, knee cartilage, paradoxically, needs to be placed under mechanical stress, as happens whenever we take a step and our knees take our weight...
Deaths and cardiovascular events in heart disease patients halved by psychological interventions
Date: Oct-15-2013Psychological interventions halve deaths and cardiovascular events in heart disease patients, according to research from Athens, Greece, presented at the Acute Cardiac Care Congress 2013. The Acute Cardiac Care Congress 2013 is the annual meeting of the Acute Cardiovascular Care Association (ACCA) of the European Society of Cardiology (ESC). It took place 12-14 October in Madrid, Spain...
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