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Continuity of care could cut delays in cancer diagnosis
Date: Oct-11-2013Continuity of care so that all patients see the same GP with whom they build up a relationship over time could help reduce delays in the diagnosis of cancer in primary care. In an essay published by the Journal of the Royal Society of Medicine, a team of primary care experts write that this, together with longer consultations and better distribution of information to GPs about referral pathways or new services could have a wide reaching impact on the early diagnosis of cancer and survival...
Clinical trial examines oral supplementation in age-related macular degeneration
Date: Oct-11-2013A daily 15 mg dose of the oral medication pazopanib for patients with age-related macular degeneration (AMD, a leading cause of blindness) resulted in improvements in vision and other measures related to the retina, according to a report of two clinical trials by Megan M. McLaughlin, M.S., of GlaxoSmithKline, King of Prussia, Pa., and colleagues. Most of the vision loss caused by AMD is connected to new blood vessel formation in the retina, according to the study background. Treatment with a drug that blocks new blood vessel formation is effective but must be given by injection in the eye...
Study examines characteristics of thyroid cancer
Date: Oct-11-2013Patients whose thyroid cancer is incidentally discovered on imaging performed for reasons other than evaluation of the thyroid gland tend to be older, male and have a higher stage of the disease at diagnosis, but there did not appear to be differences in tumor characteristics such as size and metastases compared with patients whose cancer was found after targeted thyroid evaluation, according to a study published Online First by JAMA Otolaryngology - Head & Neck Surgery...
Improved wound healing with gene and stem cell therapy combination
Date: Oct-11-2013Findings in elderly mice offer insight into helping elderly people recover from burns Johns Hopkins researchers, working with elderly mice, have determined that combining gene therapy with an extra boost of the same stem cells the body already uses to repair itself leads to faster healing of burns and greater blood flow to the site of the wound. Their findings offer insight into why older people with burns fail to heal as well as younger patients, and how to potentially harness the power of the body's own bone marrow stem cells to reverse this age-related discrepancy...
Evaluations of surgical skill and outcomes
Date: Oct-11-2013Video ratings data of surgeons' operating skills successfully predicted whether patients would suffer complications after they leave the operating room, according to a University of Michigan Health System study. The study assessed the relationship between the technical skill of 20 bariatric surgeons and post-surgery complications in 10,343 patients undergoing common, but complex laparoscopic gastric bypass surgery...
In study of 14 million patients, whites found to be more prone to atrial fibrillation than other ethnic groups
Date: Oct-11-2013An individual's race or ethnic background could be a determining factor when it comes to risk of atrial fibrillation, the most frequently diagnosed type of irregular heart rhythm, according to researchers at UC San Francisco. In a study to be published online and in the November 12 issue of Circulation, researchers discovered that self-described non-Hispanic whites are more likely to develop atrial fibrillation than people from other race or ethnic groups...
Safer drug combinations possible using available data
Date: Oct-11-2013Using the Food and Drug Administration's Adverse Event Reporting System (FAERS), a hospital electronic health records database, and an animal model, a team of researchers at the Icahn School of Medicine at Mount Sinai report that by adding a second drug to the diabetes drug rosiglitazone, adverse events dropped enormously. That suggests that drugs could be repurposed to improve drug safety, including lowering the risk of heart attacks. The research is published online in the journal Science Translational Medicine...
Regenerating defective heart tissue in babies using amniotic stem cells
Date: Oct-11-2013Researchers at the University of Michigan Department of Surgery have begun testing an alternative to embryonic stem cells that could one day regenerate muscle tissue for babies with congenital heart defects. A research-in-progress report on this new approach, which uses amniotic stem cells, was presented at the 2013 Clinical Congress of the American College of Surgeons. Although this research is still in an early phase, this new approach has the potential to one day help thousands of babies born each year with congenital heart defects...
Researchers discover new avenue for preventing and treating fatal prion disease
Date: Oct-11-2013Case Western Reserve University researchers have published findings that point to a promising discovery for the treatment and prevention of prion diseases, rare neurodegenerative disorders that are always fatal. The researchers discovered that recombinant human prion protein stops the propagation of prions, the infectious pathogens that cause the diseases...
Making progress toward a treatment for dangerous allergies
Date: Oct-11-2013New research published in the journal Nature Chemical Biology shows that a group of scientists, led by faculty at the University of Notre Dame, has made concrete progress toward the development of the first-ever inhibitory therapeutic for Type I hypersensitive allergic reactions...
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