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Nerve signal and hormone transport discoveries win Nobel prize

Date: Oct-08-2013
Research that offers insights into diseases such as Alzheimer's, autism and diabetes has won the Nobel Prize for medicine for three US-based medical scientists who unravelled the way that cells transport materials, such as hormones and nerve transmitters. James Rothman, Randy Schekman and Thomas Südhof were awarded the prize, announced in Stockholm on October 7th...

Nipple injections to treat breast cancer

Date: Oct-08-2013
Doctors in Boston, MA, are investigating the possibility of administering drugs directly into the milk ducts via the nipple to treat breast cancer. According to the American Cancer Society, breast cancer is the second most common cancer among American women after skin cancers. They estimate that 1 in 8 women will develop invasive breast cancer during their lifetimes. On a positive note, death rates from breast cancer have been declining since 1989, probably due to earlier detection and improved treatments, and there are currently more than 2...

2025 action plan to cut deaths from disease by a quarter

Date: Oct-08-2013
Health leaders from across the Americas have agreed a pledge to cut the number of deaths caused by non-communicable diseases by 25% by the year 2025. The action plan has been agreed by the Pan American Health Organization (PAHO). This is a regional body of the World Health Organization (WHO) and the world's oldest international public health organization, working with all the countries of the Americas to improve health and quality of life. PAHO says the leading causes of death in the Americas, excluding infections, are preventable...

Scientists print microscopic 3D cages to study bacteria

Date: Oct-08-2013
Bacteria in the human body thrive in 3D structured communities, so studying pathogens in this type of environment could better show how they interact. Now, scientists are doing just that - with microscopic 3D printed cages. Scientists from the University of Texas at Austin have used a new 3D printing technology, which allowed them to construct homes for the bacteria at a micro level. By encasing bacteria in these tiny homes, they were able to study how bacteria found in the human gut and lungs collaborate to develop infections...

A better way to make antibody-guided therapies

Date: Oct-08-2013
Chemists at The Scripps Research Institute (TSRI) have devised a new technique for connecting drug molecules to antibodies to make advanced therapies. Antibody-drug conjugates, as they're called, are the basis of new therapies on the market that use the target-recognizing ability of antibodies to deliver drug payloads to specific cell types - for example, to deliver toxic chemotherapy drugs to cancer cells while sparing most healthy cells. The new technique allows drug developers to forge more stable conjugates than are possible with current methods...

Triathletes feel less pain

Date: Oct-08-2013
A new study from Israel finds that triathletes feel less pain than casual exercisers. If further research shows that intense training has given them this ability, then it could be a way to treat chronic pain sufferers. Triathletes train and compete in a gruelling mix of three endurance sports: swimming, cycling and long-distance running, without rest. They push themselves beyond what most of us can endure. However, we know very little about what gives them these abilities...

Fetal development affected by air pollution and mother's psychological distress

Date: Oct-08-2013
Maternal psychological distress combined with exposure to air pollution during pregnancy have an adverse impact on the child's behavioral development, according to researchers at the Columbia Center for Children's Environmental Health at the Mailman School of Public Health...

Parkinson's disease clue may lie just under the skin

Date: Oct-08-2013
By discovering that a nervous system protein tends to accumulate at a higher level just under the skin in patients with Parkinson's disease, researchers believe they may have revealed an important clue to diagnosing Parkinson's disease. Despite being the most frequently occurring neurodegenerative disease in the US, where it affects over 1 million people, Parkinson's disease is difficult to diagnose: there are no standard clinical tests...

Kidney disease of unknown causes in agricultural communities in Central America is declared a serious public health problem

Date: Oct-08-2013
Ministers of health from throughout the Americas said this week that chronic kidney disease of unknown causes that has claimed thousands of lives in agricultural communities in Central America is a serious public health problem. They called for stepped-up efforts to investigate and address the environmental and occupational factors believed to underlie the problem...

Myriad's myRisk Hereditary Cancer™ test improves colon cancer testing by 60 percent

Date: Oct-08-2013
Myriad Genetics, Inc. (NASDAQ: MYGN) has announced new clinical data from a study with myRisk Hereditary Cancer, a 25-gene hereditary cancer panel, that showed a 60 percent increase in mutations detected in cancer predisposition genes in patients with a prior history of colon cancer and/or polyps. Myriad is presenting this clinical study at the Collaborative Group of the Americas on Inherited Colorectal Cancer (CGA) Annual Meeting in Anaheim, Calif. Patients with a family history of colon cancer also are vulnerable to other cancers including breast, ovarian, endometrial and stomach cancer...