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Biologists discover new method for discovering antibiotics

Date: Sep-17-2013
Biologists at the University of California, San Diego have developed a revolutionary new method for identifying and characterizing antibiotics, an advance that could lead to the discovery of new antibiotics to treat antibiotic resistant bacteria. The researchers, who published their findings in this week's early online edition of the journal Proceedings of the National Academy of Sciences, made their discovery by developing a way to perform the equivalent of an autopsy on bacterial cells...

Clinical Biomechanics publishes a study proving the excellent performances of the SpineJack®

Date: Sep-17-2013
VEXIM (FR0011072602 - ALVXM), a medical device company specializing in the minimally-invasive treatment of vertebral fractures, has announces that the results of a comparative biomechanical study carried out by Marburg University's Traumatology department (Germany) were published in the August issue of the CLINICAL BIOMECHANICS international journal. The aim of this study was to evaluate the anatomic restoration of 36 fractured vertebral bodies with osteoporosis and the maintaining of the gained height after recompression by comparing the SpineJack® and balloon kyphoplasty techniques...

Researchers capture speedy chemical reaction in mid-stride

Date: Sep-17-2013
In synthetic chemistry, making the best possible use of the needed ingredients is key to optimizing high-quality production at the lowest possible cost. The element rhodium is a powerful catalyst - a driver of chemical reactions - but is also one of the rarest and most expensive. In addition to its common use in vehicle catalytic converters, rhodium is also used in combination with other metals to efficiently drive a wide range of useful chemical reactions...

Report: Climate change to shift Kenya's breadbaskets

Date: Sep-17-2013
Kenyan farmers and agriculture officials need to prepare for a possible geographic shift in maize production as climate change threatens to make some areas of the country much less productive for cultivation while simultaneously making others more maize-friendly, according to a new report prepared by the International Food Policy Research Institute (IFPRI) and the Association for Strengthening Agricultural Research in Eastern and Central Africa (ASARECA)...

Pinpointing molecular path that makes antidepressants act quicker in mouse model

Date: Sep-17-2013
The reasons behind why it often takes people several weeks to feel the effect of newly prescribed antidepressants remains somewhat of a mystery - and likely, a frustration to both patients and physicians. Julie Blendy, PhD, professor of Pharmacology, at the Perelman School of Medicine, University of Pennsylvania; Brigitta Gunderson, PhD, a former postdoctoral fellow in the Blendy lab, and colleagues, have been working to find out why and if there is anything that can be done to shorten the time in which antidepressants kick in...

Several common differentially expressed genes between Kashin-Beck disease and Keshan disease

Date: Sep-17-2013
Kashin-Beck disease (KBD) and Keshan disease (KD) are major endemic diseases in China. Postgraduate Xi Wang et al., under the guidance of Professor Xiong Guo from the Institute of Endemic Diseases of the Faculty of Public Health, Medicine College of Xi'an Jiaotong University, Key Laboratory of Environment and Gene Related Diseases in Ministry of Education, Key Laboratory of Trace Elements and Endemic Diseases of Health Ministry, set out to tackle these two endemic diseases...

New findings from UNC School of Medicine challenge assumptions about origins of life

Date: Sep-17-2013
Before there was life on Earth, there were molecules. A primordial soup. At some point a few specialized molecules began replicating. This self-replication, scientists agree, kick-started a biochemical process that would lead to the first organisms. But exactly how that happened - how those molecules began replicating - has been one of science's enduring mysteries. Now, research from UNC School of Medicine biochemist Charles Carter, PhD, appearing in the September 13 issue of the Journal of Biological Chemistry, offers an intriguing new view on how life began...

Fish skin immune responses resemble that of the gut, Penn study finds

Date: Sep-17-2013
Fish skin is unique in that it lacks keratin, the fibrous protein found in mammalian skin that provides a barrier against the environment. Instead, the epithelial cells of fish skin are in direct contact with the immediate environment: water. Similarly, the epithelial cells that line the gastrointestinal tract are also in direct contact with their immediate milieu. "I like to think of fish as an open gut swimming," said J. Oriol Sunyer, a professor in the the Department of Pathobiology of the University of Pennsylvania School of Veterinary Medicine...

UNC research points to promising treatment for macular degeneration

Date: Sep-17-2013
Researchers at the University of North Carolina School of Medicine today published new findings in the hunt for a better treatment for macular degeneration. In studies using mice, a class of drugs known as MDM2 inhibitors proved highly effective at regressing the abnormal blood vessels responsible for the vision loss associated with the disease...

Diets low in polyunsaturated fatty acids may be a problem for youngsters

Date: Sep-17-2013
In the first study to closely examine the polyunsaturated fatty acid (PUFA) intake among U.S. children under the age of 5, Sarah Keim, PhD, principal investigator in the Center for Biobehavioral Health at The Research Institute at Nationwide Children's Hospital, has found what might be a troubling deficit in the diet of many youngsters. The study, published online by Maternal and Child Nutrition, used data on nearly 2500 children age 12 to 60 months from the U.S. National Health and Nutrition Examination Survey. PUFAs are essential to human health...