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No racial difference for survival in African American versus Caucasian lung cancer patients
Date: Sep-06-2013According to the American Cancer Society, an estimated 160,340 lung cancer deaths occurred in the United States in 2012, accounting for 28 percent of all cancer deaths. While survival from lung cancer has improved since the early 1990s, racial differences in lung cancer survival persist such that blacks experience poorer 5-year survival for lung cancer compared to whites...
Data suggests Abbott's test may help more accurately diagnose heart attacks in women
Date: Sep-06-2013Abbott has announced promising preliminary results from a study presented at the ESC Congress 2013, suggesting that its high sensitive troponin test may help doctors improve the diagnosis and prognosis of patients presenting with symptoms of a heart attack.[1] The test could be particularly beneficial for women, who may have different presenting symptoms and are often under-diagnosed.[2] The study, which is being conducted by researchers at the University of Edinburgh, is evaluating Abbott's ARCHITECT STAT High Sensitive Troponin-I (hsTnI) test, which received CE Mark in January 2013...
Discovery helps to unlock brain's speech-learning mechanism
Date: Sep-06-2013USC scientists have discovered a population of neurons in the brains of juvenile songbirds that are necessary for allowing the birds to recognize the vocal sounds they are learning to imitate. These neurons encode a memory of learned vocal sounds and form a crucial (and hitherto only theorized) part of the neural system that allows songbirds to hear, imitate, and learn its species' songs - just as human infants acquire speech sounds...
Stress-related protein speeds progression of Alzheimer's disease
Date: Sep-06-2013A stress-related protein genetically linked to depression, anxiety and other psychiatric disorders contributes to the acceleration of Alzheimer's disease, a new study led by researchers at the University of South Florida has found. The study is published online in the Journal of Clinical Investigation. When the stress-related protein FKBP51 partners with another protein known as Hsp90, this formidable chaperone protein complex prevents the clearance from the brain of the toxic tau protein associated with Alzheimer's disease...
French Tour de France cyclists live longer than their non-cyclist countrymen
Date: Sep-06-2013French participants in the Tour de France between 1947-2012 lived longer than their same-age French counterparts according to the results of a study marking the centenary of the race this year. "In the context of recent concerns regarding performance-enhancing techniques and the potential negative health effects of excessive high-level physical activity, data on the long-term outcomes and causes of death in elite endurance cyclists is of particular interest," said Xavier Jouven, MD, PhD, from the Sudden Death Expertise Center in Paris, France...
Youthful stem cells from bone can heal the heart, Temple scientists report
Date: Sep-06-2013Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center (CVRC) recently found hope in an unlikely source - stem cells in cortical, or compact, bone. In a new study, they show that when it comes to the regeneration of heart tissue, these novel bone-derived cells do a better job than the heart's own stem cells. According to the study's senior investigator, Steven R...
Researchers develop new way to control genes
Date: Sep-06-2013Scientists have discovered a way to switch genes on or off inside yeast and human cells by controlling the point at which DNA is copied into messenger RNA, according to a study published in the journal ACS Synthetic Biology. Researchers from Massachusetts Institute of Technology (MIT) say that this discovery could enable scientists to better understand the role of the genes, make it easier to engineer cells and lead to better drugs and treatments. The new method is based on a system called CRISPR, which is made up of two components...
Blood pressure drug tends to slow coronary disease research finds
Date: Sep-06-2013Patients with clogged and hardened arteries who already have their blood pressure under control may benefit from an additional blood pressure-lowering medication, according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C5Research). The researchers found that the renin-inhibitor aliskiren tended to slow coronary disease progression and reduced the risk of death, stroke and heart attack in these patients by about 50 percent, compared to placebo, suggesting that patients with prehypertension may benefit from blood pressure lowering drugs...
Robotic surgery complications underreported, Johns Hopkins Study suggests
Date: Sep-06-2013Despite widespread adoption by hospitals of surgical robot technology over the past decade, a "slapdash" system of reporting complications paints an unclear picture of its safety, according to Johns Hopkins researchers. In a report published online in the Journal for Healthcare Quality, the Johns Hopkins team says that of the 1 million or so robotic surgeries performed since 2000, only 245 complications - including 71 deaths - were reported to the U.S. Food and Drug Administration...
Study examines ways to restore immunity to chronic hepatitis C infection
Date: Sep-06-2013The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore immune function, allowing the body to fight infection. The work, led by teams at The Research Institute at Nationwide Children's Hospital and Emory University, was published online Aug. 26 in the Proceedings of the National Academy of Sciences. Previous studies show that antibody treatments that inhibit the protein, called programmed cell death 1 (PD-1), can shrink tumors in humans...
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