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Discovery of novel way gene controls stem cell self-renewal
Date: Aug-27-2013Stem cell scientists at the Princess Margaret Cancer Centre have discovered the gene GATA3 has a role in how blood stem cells renew themselves, a finding that advances the quest to expand these cells in the lab for clinical use in bone marrow transplantation, a procedure that saves thousands of lives every year...
Fish acquire more mercury at depth due to photochemical reactions breaking down mercury at the ocean surface
Date: Aug-27-2013Mercury - a common industrial toxin - is carried through the atmosphere before settling on the ocean and entering the marine food web. Now, exciting new research from the University of Michigan and the University of Hawai'i at Manoa School of Ocean and Earth Science and Technology (SOEST) combines biogeochemistry and direct marine ecology observations to show how the global mercury cycle is colliding with ocean fish - and the human seafood supply - at different depths in the water...
Glutathione peroxidase activity improves symptoms in models of Huntington's disease
Date: Aug-27-2013Leicester geneticists have discovered a potential defence against Huntington's disease - a fatal neurodegenerative disorder which currently has no cure. The team of University of Leicester researchers identified that glutathione peroxidase activity - a key antioxidant in cells - protects against symptoms of the disease in model organisms. They hope that the enzyme activity - whose protective ability was initially observed in model organisms such as yeast - can be further developed and eventually used to treat people with the genetically-inherited disease...
Multi-stage analysis provides strongest clues to date for causes of schizophrenia
Date: Aug-27-2013A new genome-wide association study (GWAS) estimates the number of different places in the human genome that are involved in schizophrenia. In particular, the study identifies 22 locations, including 13 that are newly discovered, that are believed to play a role in causing schizophrenia. "If finding the causes of schizophrenia is like solving a jigsaw puzzle, then these new results give us the corners and some of the pieces on the edges," said study lead author Patrick F. Sullivan, MD. "We've debated this for a century, and we are now zeroing in on answers...
The use of social networking sites to monitor romantic partners
Date: Aug-27-2013With the widespread popularity of social networking sites such as Facebook, it is increasingly common for people to use interpersonal electronic surveillance to monitor the activities of current and former romantic partners. They can gather information on partners anonymously, view past and current photos and audio and video clips, and look for clues to explain any "suspicious" behaviors. Why some individuals engage in this type of behavior more than others is the subject of an article in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc...
The polarizing effect of physiological arousal
Date: Aug-27-2013The idea of having to negotiate over the price of a new car sends many into the cold sweats, but new research published in Psychological Science, a journal of the Association for Psychological Science, suggests that sweaty palms and a racing heart may actually help some people in getting a good deal. As researchers Ashley D. Brown and Jared R...
Risk of crohn's disease affected by gene combinations and interactions
Date: Aug-27-2013A statistical model accounting for dozens of different genes in combination - and the interactions between them - is an important step forward in understanding the genetic factors affecting the risk of Crohn's disease (CD), reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health...
Racial/ethnic differences in young people with cancer
Date: Aug-27-2013Mei-Chin Hsieh, MSPH, CTR, of LSU Health Sciences Center New Orleans School of Public Health's Louisiana Tumor Registry, is the lead author of a study that reports racial and ethnic differences in the incidence of soft tissue sarcomas in adolescents and young adults. The research*, conducted at LSU Health Sciences Center New Orleans School of Public Health, is published online in the Journal of Adolescent and Young Adult Oncology...
Abnormal gut taste mechanisms discovered in diabetics
Date: Aug-27-2013Researchers at the University of Adelaide have discovered that the way the gut "tastes" sweet food may be defective in sufferers of type 2 diabetes, leading to problems with glucose uptake. This is the first time that abnormal control of so-called "sweet taste receptors" in the human intestine has been described by researchers. The work could have implications for a range of health and nutrition problems experienced by diabetes patients...
Brain cancer patients benefit from Vessel Architectural Imaging
Date: Aug-27-2013A new scanning technique developed by Danish and US researchers reveals how susceptible patients with aggressive brain cancer are to the drugs they receive. The research behind the ground-breaking technique has just been published in Nature Medicine. Each year sees 260 new cases of the most aggressive type of brain cancer in Denmark. Some patients survive only a few months, while others survive for 18 months. Only very few, 3.5%, are alive five years after their diagnosis...
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