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Groundbreaking discovery reveals that untying knots promotes cancer

Date: Aug-22-2013
Researchers have long known that high levels of a specific protein in human cells are linked to tumor growth - but no one has fully understood how. Now, a groundbreaking discovery by UC Davis graduate student Kateryna Feoktistova and Assistant Professor Christopher Fraser illuminates the way that the protein, eukaryotic initiation factor 4E (eIF4E), acts upon cancer-promoting messenger RNA molecules. When translated, this type of mRNA can trigger the runaway cell replication that results in malignancies...

Musical hallucinations, memory and forgetting

Date: Aug-22-2013
One night when she was trying to fall asleep, a 60-year-old woman suddenly began hearing music, as if a radio were playing at the back of her head. The songs were popular tunes her husband recognized when she sang or hummed them. But she herself could not identify them. This is the first known case of a patient hallucinating music that was familiar to people around her, but that she herself did not recognize, according to Dr. Danilo Vitorovic and Dr. José Biller of Loyola University Medical Center. The neurologists describe the unique case in the journal Frontiers in Neurology...

Online tool for planning life after cancer empowers cancer patients

Date: Aug-22-2013
In 2005, the Institute of Medicine, surveying the outlook for the growing number of American cancer survivors, first described the idea of a survivorship care plan: a roadmap for the group of patients, today numbering nearly 12 million, who are beginning new lives as cancer survivors. Care plans aims to arm cancer survivors with a customized road map for their lives as cancer survivors: tips for follow-up screenings, information about possible late effects of their therapies, and pointers on fertility or financial issues they may face in the future...

Repeat intimate-partner violence reduced by community intervention program

Date: Aug-22-2013
Mothers who completed a mandatory community intimate-partner violence (IPV) program were less likely to be re-victimized and more likely to leave an abusive spouse or partner, say researchers at the University of North Carolina at Chapel Hill. "Changes in Intimate Partner Violence Among Women Mandated to Community Services" was published online recently in the journal Research and Social Work Practice. Rebecca Macy, L. Richardson Preyer Distinguished Chair for Strengthening Families and professor in UNC's School of Social Work, directed the five-year study...

Holocaust memorial trips are serious stressors for Israeli high school students

Date: Aug-22-2013
A new study led by Tel Aviv University researchers finds that the Holocaust education trips Israeli high school students take to Poland every year can trigger mental health problems. About a third of the psychiatric professionals surveyed in this pilot study said they had treated teenagers for psychological problems arising from the Holocaust education trips. While most of the teenagers were treated for less severe symptoms such as anxiety, adjustment, and mood disorders, reports also cited hospitalization, post-traumatic-stress disorder, and psychosis...

Men with diet-induced erectile dysfunction may benefit from hitting the gym

Date: Aug-22-2013
Obesity continues to plague the U.S. and now extends to much of the rest of the world. One probable reason for this growing health problem is more people worldwide eating the so-called Western diet, which contains high levels of saturated fat, omega-6 polyunsaturated fatty acids (the type of fat found in vegetable oil), and added sugar. Researchers have long known that this pattern of consumption, as well as the weight gain it often causes, contributes to a wide range of other health problems including erectile dysfunction and heart disease...

Diabetes link to antipsychotic use in adolescents

Date: Aug-22-2013
Children and adolescents prescribed antipsychotic medications may be at higher risk of developing type 2 diabetes, according to a study published in JAMA Psychiatry. Researchers from the Vanderbilt University School of Medicine in Nashville, TN, conducted a study of children and youths between 6 and 24 years of age, who were a part of the Tennessee Medicaid program between 1996 and 2007. In the analysis, 28,858 children and youths were recently prescribed antipsychotic drugs, while 14,429 control patients were prescribed alternative psychotropic medication...

A simple joystick task could reduce social stress

Date: Aug-22-2013
People who are socially anxious show a strange contradictory reaction to smiling faces: they say that these faces are pleasant, yet automatically avoid them. In a study in Frontiers in Human Neuroscience, researchers report that this avoidance of smiling faces is one of the reasons for the social fear that socially anxious individuals feel. In the experiment, 32 socially anxious participants performed a simple, short joystick task 240 times. By pulling or pushing the joystick, they pulled images on the computer screen closer to themselves or pushed them away...

First pre-clinical gene therapy study to reverse Rett symptoms

Date: Aug-22-2013
The concept behind gene therapy is simple: deliver a healthy gene to compensate for one that is mutated. New research published in the Journal of Neuroscience suggests this approach may eventually be a feasible option to treat Rett Syndrome, the most disabling of the autism spectrum disorders. Gail Mandel, Ph.D., a Howard Hughes Investigator at Oregon Health and Sciences University, led the study. The Rett Syndrome Research Trust, with generous support from the Rett Syndrome Research Trust UK and Rett Syndrome Research & Treatment Foundation, funded this work through the MECP2 Consortium...

In breast cancer proliferation, NEETs are prime suspects

Date: Aug-22-2013
Two proteins have been identified as prime suspects in the proliferation of breast cancer in a study by an international consortium of researchers from Rice University, the University of North Texas, Denton (UNT); the University of California, San Diego (UCSD); and the Hebrew University of Jerusalem. The research, which appears this week in the Proceedings of the National Academy of Sciences' Online Early Edition, may offer a path to therapies that could slow or stop tumors from developing...