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QS inhibitor compounds offer potential for the treatment of P. aeruginosa infections
Date: Aug-15-2013The fight against antibiotic-resistant superbugs has taken a step forward thanks to a new discovery by scientists at The University of Nottingham. A multi-disciplinary research team at the University's Centre for Biomolecular Sciences has uncovered a new way of inhibiting the toxicity and virulence of the notorious superbug, Pseudomonas aeruginosa. This bacteria produces an armoury of virulence factors and is resistant to many conventional antibiotics. It is almost impossible to eradicate P...
Children with high-risk neuroblastoma benefit from new, precise proton therapy cancer treatment
Date: Aug-15-2013Proton therapy, using high-energy subatomic particles, may offer a precise, organ-sparing treatment option for children with high-risk forms of neuroblastoma. For patients in a new study of advanced radiation treatment, proton therapy spared the liver and kidneys from unwanted radiation, while zeroing in on its target. "As survival rates improve for children with neuroblastoma, we need to reduce treatment-related long-term toxicities," said study leader Christine Hill-Kayser, MD, a radiation oncologist in The Children's Hospital of Philadelphia's (CHOP) Cancer Center...
Association between childhood physical abuse and obesity in women
Date: Aug-15-2013Women with a history of childhood physical abuse are more likely to become obese adults, according to a new study by University of Toronto researchers. Results indicate that women who were physically abused in childhood were more likely to be obese than women from non-abusive homes. "After adjusting for age and race, childhood physical abuse was associated with 47% higher odds of obesity for women" says lead author Esme Fuller-Thomson, Professor and Sandra Rotman Endowed Chair in the University of Toronto's Factor-Inwentash Faculty of Social Work...
Employers can play a role in cancer prevention and treatment
Date: Aug-15-2013Employers can have a significant role in improving efforts to prevent and treat diseases such as cancer by introducing and supporting health promotion programs in the workplace. Together, companies can influence health care policies and reimbursement and industry practices to support the fight against cancer. Johnson & Johnson's active role in implementing the CEO Cancer Gold Standard program is described in an article in Population Health Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Population Health Management website...
Seeking ways to effectively control bacteria in the water supply
Date: Aug-15-2013Research at the University of Sheffield, published in the latest issue of Water Science and Technology: Water Supply, points the way to more sophisticated and targeted methods of ensuring our drinking water remains safe to drink, while still reducing the need for chemical treatments and identifying potential hazards more quickly. The research team, from the University of Sheffield's Faculty of Engineering, studied four bacteria found in the city's drinking water to see which combinations were more likely to produce a 'biofilm'...
NAS panel 'misled the world' when adopting radiation exposure guidelines, Toxicologist says
Date: Aug-15-2013Toxicologist Edward Calabrese reviews how a linear dose-response approach to ionizing radiation exposure was adopted and offers evidence supporting his view that 2 geneticists suppressed evidence to keep the NAS from considering a non-linear model In two recently published peer-reviewed articles, toxicologist Edward Calabrese of the University of Massachusetts Amherst describes how regulators came to adopt the linear no threshold (LNT) dose-response approach to ionizing radiation exposure in the 1950s, which was later generalized to chemical carcinogen risk assessment...
Success of experimental technique may open new route for transcatheter valve replacement
Date: Aug-15-2013Doctors at Henry Ford Hospital have created a new route to the heart to implant an artificial heart valve by temporarily connecting major blood vessels that do not normally intersect. In a July 3 operation on 79-year-old Viola Waller of Charlevoix, physicians performed a world-first cardiac procedure when it became evident that other means would not work. "I knew of an experimental technique that had not yet been done in humans, and I had a patient with no other options who was failing rapidly," says William O'Neill, M.D...
Breastfeeding cuts breast cancer risks for moms
Date: Aug-15-2013Women who breastfeed for over 6 months are less likely to develop early breast cancer than women who do not breastfeed - as long as they do not smoke - a nurse-led study suggests. Emilio Gonzalez-Jimenez PhD, of the University of Granada in Spain, and his colleagues drew from the medical records of 504 women (between 19 and 91 years of age) who had been treated for breast cancer at one of the city's hospitals. Women who had not breastfed their babies were, on average, found to get breast cancer 10 years earlier than breastfeeding mothers...
Low-grade prostate cancers may not become aggressive with time - adds support for "watch and wait" approach
Date: Aug-15-2013Prostate cancer aggressiveness may be established when the tumor is formed and not alter with time, according to a study published in Cancer Research, a journal of the American Association for Cancer Research. Researchers found that after the introduction of widespread prostate-specific antigen (PSA) screening, the proportion of patients diagnosed with advanced-stage cancers dropped by more than six-fold in 22 years, but the proportion diagnosed with high Gleason grade cancers did not change substantially...
Embarrassment leads to a preference for products that help people 'save face'
Date: Aug-15-2013People who are feeling embarrassed are more likely to choose items that hide or 'repair' the face, according to new research published in Psychological Science, a journal of the Association for Psychological Science. The research indicates that feelings of embarrassment can be alleviated by using so-called 'restorative' products - effectively helping people to "save face...
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