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New hope for improved TB treatments
Date: Aug-12-2013Researchers at the University of Southampton have identified new markers of tuberculosis (TB) that may help in the development of new diagnostic tests and treatments. Published online in the Journal of Infectious Diseases, the study investigated the proteins that are released by a break down of the lung structure in TB patients. Lung damage causes both transmission of infection and mortality. They found that fragments released by break down of the lung's key proteins (collagen and elastin), are increased in the sputum of patients with TB...
A complex story behind genes, environment, diabetes and obesity
Date: Aug-12-2013While it is well known that there is a strong genetic basis to both diabetes and obesity, and that they are linked, Australian researchers say that there are many rare genetic variants involved, which will pose a significant challenge in the quest to develop effective therapies. Type 2 diabetes is a metabolic disorder that occurs when the body becomes less able to produce and use insulin effectively, a hormone essential for maintaining normal metabolism of food. The disorder is commonly associated with a high-sugar, high-fat diet combined with lack of exercise...
LDR receives FDA approval for the Mobi-C Cervical Disc for one-level use
Date: Aug-12-2013LDR, a privately held medical device company offering exclusive spinal implant technologies for both non-fusion and fusion applications, today announced that it has received a letter of approval from the U.S. Food and Drug Administration (FDA) allowing the commercial sale and distribution of the Mobi-C® Cervical Disc (Mobi-C), for one-level indications in the United States...
Scientists identify biomarker to predict immune response risk after stem cell transplants
Date: Aug-12-2013Researchers from Indiana University, the University of Michigan, the Fred Hutchinson Cancer Research Center and the Dana-Farber Cancer Institute have identified and validated a biomarker accessible in blood tests that could be used to predict which stem cell transplant patients are at highest risk for a potentially fatal immune response called graft-versus-host disease...
Occupational cancer now leading cause of compensated work-related deaths in Canada
Date: Aug-12-2013Occupational cancer is now the leading cause of compensated work-related deaths in Canada, surpassing those from accidents and injuries, according to new research published today in CMAJ Open. An analysis of data from the Association of Workers' Compensation Boards of Canada from 1997 - 2010 to understand trends in financial compensation for deaths shows that lung cancer is the most commonly compensated workplace cancer...
Pomalidomide Celgene® - (pomalidomide) licensed for use in the UK for the treatment of adults with relapsed/refractory multiple myeloma
Date: Aug-12-2013Celgene has confirmed that Pomalidomide Celgene® - (pomalidomide), a new oral blood cancer therapy, has been granted Marketing Authorisation by the European Medicines Agency and is now available in the UK and Ireland. Pomalidomide is for use in combination with dexamethasone for the treatment of adults with relapsed and refractory multiple myeloma (rrMM) who have received at least two prior therapies including both lenalidomide and bortezomib, and have demonstrated disease progression while on their last therapy...
Eye expert urges people to take a contact lens break while on holiday
Date: Aug-12-2013A leading eye expert based at Southampton's university hospitals is urging people to take a break from contact lenses while on holiday to cut the risk of developing sight-threatening infections. Parwez Hossain, a consultant ophthalmologist at Southampton General Hospital, said attendances at his eye unit's casualty department "almost always" rose in the first week of August through to mid-September as a result of poor lens hygiene and accidents during the summer holidays...
Researchers Identify Gene Variations in Lung Cancer Patients That May Help Predict an Individual's Treatment Response
Date: Aug-12-2013Researchers at the Moffitt Cancer Center have identified four inherited genetic variants in non-small cell lung cancer patients that can help predict survival and treatment response. Their findings could help lead to more personalized treatment options and improved outcomes for patients. The researchers analyzed DNA sequence variations in 651 non-small cell lung cancer patients, paying close attention to 53 inflammation-related genes. They found that four of the top 15 variants associated with survival were located on one specific gene (TNFRSF10B)...
Low Childhood Conscientiousness Predicts Adult Obesity
Date: Aug-12-2013Results from a longitudinal study show that children who exhibit lower conscientiousness (e.g., irresponsible, careless, not persevering) could experience worse overall health, including greater obesity, as adults. The Oregon Research Institute (ORI) study examines the relationship between childhood personality and adult health and shows a strong association between childhood conscientiousness (organized, dependable, self-disciplined) and health status in adulthood. ORI scientist Sarah Hampson, Ph.D...
New 2011-12 data on health of Californians: California health interview survey
Date: Aug-12-2013The California Health Interview Survey (CHIS) released new data based on interviews with more than 44,000 households in California. The survey, conducted by the UCLA Center for Health Policy Research, covered hundreds of topics affecting state residents' health and well-being. (See a complete list of topics here.) Data on nearly 200 of these topics were released on AskCHIS, the center's award-winning, free, easy-to-use Web tool that provides data by state, region, county and some service-planning areas in Los Angeles and San Diego counties...
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