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Association between grape consumption and healthier eating patterns in US children and adults

Date: Aug-06-2013
In a new observational study published in the Journal of Food Science, researchers looked at the association of grape consumption, in the non-alcoholic forms most commonly consumed - fresh grapes, raisins and 100% grape juice - with the diet quality of a recent, nationally representative sample of U.S. children and adults. Their findings suggest that, among adults and children, consumption of grapes and grape products is associated with healthier dietary patterns and improved nutrient intakes...

First successful laboratory model for studying hepatitis C

Date: Aug-06-2013
By differentiating monkey stem cells into liver cells and inducing successful infection, researchers from the Icahn School of Medicine at Mount Sinai have shown for the first time that the hepatitis C virus (HCV) can replicate in monkeys, according to research published in the journal Gastroenterology. The new findings may lead to the first new animal model and provide new avenues for developing treatments and vaccines for this disease, which impacts more than three million people in the United States...

Stemming Bleeding Caused by Warfarin

Date: Aug-06-2013
Prothrombin complex concentrates (PCCs) are faster and more effective than fresh frozen plasma at reversing hemorrhage caused by the anti-coagulant warfarin, despite plasma being the most commonly used therapy. A literature review published last month in Annals of Emergency Medicine suggests that physicians in the United States should join those around the world in following recommendations of multiple specialty organizations to use PCCs as the first line of defense in this common and life-threatening emergency...

Lixisenatide for diabetes: Added benefit not proven

Date: Aug-06-2013
Drug manufacturer's dossier did not contain suitable data for any therapeutic indication Lixisenatide (trade name: Lyxumia) has been approved in Germany since February 2013 for the treatment of type 2 diabetes mellitus in combination with oral blood-glucose lowering drugs or basal insulin when these, together with diet and exercise, do not provide adequate glycaemic control...

New GAO report on physician self-referral abuse in prostate cancer treatment

Date: Aug-06-2013
ASTRO Chairman Michael L. Steinberg, MD, FASTRO, called attention to the Government Accountability Office's (GAO) striking report, "Medicare: Higher Use of Costly Prostate Cancer Treatment by Providers Who Self-Refer Warrants Scrutiny," that details clear mistreatment of patients who trusted their physicians to care for their prostate cancer. Dr. Steinberg and radiation oncologists nationwide called on Congress to pass the "Promoting Integrity in Medicare Act of 2013" (PIMA), introduced earlier today by Rep. Jackie Speier (D-Calif.) and Rep. Jim McDermott (D-Wash...

'Junk DNA' and cell development

Date: Aug-06-2013
Researchers from the Gene and Stem Cell Therapy Program at Sydney's Centenary Institute have confirmed that, far from being "junk", the 97 per cent of human DNA that does not encode instructions for making proteins can play a significant role in controlling cell development. In doing so, the researchers have unravelled a previously unknown mechanism for regulating the activity of genes, increasing our understanding of the way cells develop and opening the way to new possibilities for therapy...

Avoiding miscarriage in horses

Date: Aug-06-2013
It is not only humans that sometimes experience difficulty having children. Horses too have a low birth rate, with many pregnancies failing within the first few weeks after conception. The reason is currently unknown but recent research by the team of Christine Aurich at the University of Veterinary Medicine, Vienna (Vetmeduni) suggests that a particular class of blood cells may be involved. The results have just been made available online in the journal Reproduction, Fertility and Development...

Study could help scientists understand how gene regulation differs from one person to the next

Date: Aug-06-2013
A study of gene expression led by scientists at the EMBL-European Bioinformatics Institute (EMBL-EBI) and the University of Cambridge has revealed the first steps of evolution in gene regulation in mice. Published in the journal Cell, the research has implications for the study of differences in gene regulation between people.    Over the course of evolution in closely related mammals, certain clusters of transcription factors continue to work in concert, which is important for both genetic and evolutionary stability...

Training for surgical residents aided by novel 3-D simulation technology

Date: Aug-06-2013
A novel interactive 3-dimensional (3-D) simulation platform offers surgical residents a unique opportunity to hone their diagnostic and patient management skills, and then have those skills accurately evaluated according to a new study appearing in the August issue of the Journal of the American College of Surgeons. The findings may help establish a new tool for assessing and training surgical residents. Previous research studies have shown that the management of patient complications following operations is an extremely important skill set for surgeons to master...

K computer enables largest neuronal network simulation

Date: Aug-06-2013
By exploiting the full computational power of the Japanese supercomputer, K computer, researchers from the RIKEN HPCI Program for Computational Life Sciences, the Okinawa Institute of Technology Graduate University (OIST) in Japan and Forschungszentrum Julich in Germany have carried out the largest general neuronal network simulation to date. The simulation was made possible by the development of advanced novel data structures for the simulation software NEST...