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Bacteria hold the clues to trade-offs in financial investments and evolution

Date: Aug-06-2013
Scientists have found that bacteria have the potential to teach valuable investment lessons. The research, published in the journal Ecology Letters, takes advantage of the fact that bacteria, like humans, have limited resources and are constantly faced with investment decisions. Bacteria though are successful with their investments and have colonised every inch of the surface of our planet. The researchers, from the Universities of Exeter and Sydney, used mathematical models and lab-based synthetic biology, to predict bacterial investment crashes and boom-bust cycles...

'Pregnancy food link' to offspring addiction risk

Date: Aug-06-2013
Pregnant women who eat too many fatty and sugary foods while pregnant could be putting their children at risk of alcohol and drug problems later in life, according to studies in rats. The team of researchers was led by Dr. Nicole Avena, who recently presented her findings at the American Psychological Association's annual convention on the paradise island of Oahu. The three studies lasted around 3 months, and involved three to four rats and 10 to 12 pups in each...

Mailed outreach invitations to underserved patients for colorectal cancer screening appear to result in higher screening rate than usual care

Date: Aug-05-2013
Among underserved patients whose colorectal cancer (CRC) screening was not up to date, mailed outreach invitations appear to result in higher CRC screening compared with usual care, according to a study by Samir Gupta, M.D., M.S.C.S., of the Veterans Affairs San Diego Healthcare System, and the University of California, San Diego, and colleagues.  A total of 5,970 participants were randomly assigned to one of three groups: 1,593 to fecal immunochemical test (FIT) outreach, 479 to colonoscopy outreach, and 3,898 to usual care...

Managing chronic disease in hospitalized patients

Date: Aug-05-2013
Michael A. Steinman, M.D., and Andrew D. Auerbach, M.D., of the University of California, San Francisco, suggest "management of chronic disease in hospitalized patients is best done in coordination with the patient's outpatient clinician, if available, with two-way communication. Acute care and chronic disease care can be a difficult fit; some acute care may not match the patient's long-term needs. A thoughtful approach to managing chronic diseases in the inpatient setting can better align inpatient and outpatient care to improve outcomes both immediately and in the long term...

Long-term calcium-channel blocker use for hypertension associated with higher breast cancer risk

Date: Aug-05-2013
Long-term use of a calcium-channel blocker to treat hypertension (high blood pressure) is associated with higher breast cancer risk, according to a report published by JAMA Internal Medicine, a JAMA Network publication.  Antihypertensive medications are the most commonly prescribed class of drugs in the United States and in 2010 totaled an estimated 678 million filled prescriptions, Christopher I. Li, M.D., Ph.D., of the Fred Hutchinson Cancer Research Center, Seattle, and colleagues write in the study background...

Alzheimer disease and parkinson disease do not appear to share common genetic risk, study suggests

Date: Aug-05-2013
A study by Valentina Moskvina, Ph.D., of the Cardiff University School of Medicine, Wales, United Kingdom, and colleagues, examined the genetic overlap between Parkinson disease (PD) and Alzheimer disease (AD).  Data sets from the United Kingdom, Germany, France and the United States were used to perform a combined genome-wide association analysis (GWA). The GWA study of AD included 3,177 patients with AD and 7,277 control patients, and the GWA analysis for PD included 5,333 patients with PD and 12,298 control patients...

New drivers of glioblastoma

Date: Aug-05-2013
Several genetic drivers of glioblastomas - malignant brain tumors - are reported in an article published online this week in Nature Genetics. These discoveries shed light on how these tumors develop and suggest possible treatment options for a subset of glioblastoma patients. Glioblastoma is difficult to treat and usually associated with poor clinical outcomes. Antonio Iavarone and colleagues used a new computational platform to identify recurrent genetic changes in a large collection of glioblastoma samples...

Diabetes Innovations 2013, October 3-5, 2013, Washington, D.C.

Date: Aug-05-2013
Diabetes Innovations 2013 will bring together the best minds in health care, industry, government, insurance, research, entrepreneurship, advocacy, and patients themselves in a powerful marketplace of ideas to foster collaboration, spark innovation, and spur the development of practical and affordable solutions to the impact of diabetes and obesity on society...

Tumor cell vaccination trial to promote anti-leukemia responses

Date: Aug-05-2013
Chronic lymphocytic leukemia (CLL) is a cancer of the blood and bone marrow that most often affects older adults. CLL responds to bone marrow stem cell transplantation (allo-HSCT); however, the rate of relapse for CLL remains relatively high. A benefit of allo-HSCT is that treatment can result in the development of an anti-tumor response produced by the grafted cells and is associated with a low risk of cancer relapse...

Antioxidants do not improve fertility, study shows

Date: Aug-05-2013
A new study suggests that antioxidants do not improve a woman's chances of conceiving as previously suggested, according to researchers from the University of Auckland, New Zealand. The study, published in The Cochrane Library, found that women who take oral antioxidants are no more likely to conceive and that there was "limited information" about potential harmful effects. Other research has suggested that antioxidants could boost fertility within men...