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Simple ultrasound could prevent post-op kidney damage
Date: Aug-05-2013Acute kidney injury, in which the kidneys suddenly stop working properly, is a potentially severe condition that often follows major surgery and causes serious complications for patients. Now for the first time, researchers show that treatment with ultrasound beforehand can help prevent the problem in mice. The protection from acute kidney injury (AKI) comes from the anti-inflammatory effects of this simple, drug-free, non-invasive treatment, the scientists believe...
Making sense of medicine information leaflets
Date: Aug-05-2013You may take patient information leaflets for granted, yet behind these innocuous little slips of paper tucked into the drug packaging lies a murky sea of controversy and uncertainty. There is a delicious irony in the European Commission (EC) becoming the guardian of comprehensible labeling. This, after all, was the organization so deeply practiced in the Dark Arts of the Brussels Draft that it could produce masterpieces such as: "A compulsory [product] labeling system shall be introduced and shall be obligatory in all member states from 1 January 2000 onwards...
A roadblock to personalized cancer care? Tumor biomarker tests can help
Date: Aug-05-2013There's a major roadblock to creating personalized cancer care. Doctors need a way to target treatments to patients most likely to benefit and avoid treating those who will not. Tumor biomarker tests can help do this. The problem, according to a new commentary paper, is that, unlike drugs or other therapies, cancer biomarker tests are undervalued by doctors and patients...
Study finds physicians need to better recognize use of herbal supplements while breastfeeding
Date: Aug-05-2013In an article published in this month's issue of Pediatrics In Review, researchers from Boston University School of Medicine (BUSM) stress the importance of physicians recognizing that many mothers use herbal supplements while breastfeeding in order to make accurate health assessments for both mother and child. In the US, no existing regulatory guidelines set a standardized risk assessment of herbal supplement use during breastfeeding...
Why shopaholics overspend? Poor credit management, buying to boost mood, study says
Date: Aug-05-2013Why do shopping addicts keep spending even in the face of harmful financial, emotional and social consequences? A new study suggests poor credit management and a belief that new purchases will create a happier life fuel compulsive buying. Approximately 10 percent of adults in Western countries are believed to have a compulsive spending disorder that leads them to lose control over their buying behavior, and the trend is on the rise. These shopaholics are addicted to buying things, regardless of whether they want or need them...
Advance in regenerative medicine could make reprogrammed cells safer while improving their function
Date: Aug-05-2013The enormous promise of regenerative medicine is matched by equally enormous challenges. But a new finding by a team of researchers led by Weill Cornell Medical College has the potential to improve both the safety and performance of reprogrammed cells. The researchers' study, published in the journal Nature, found that an enzyme, activation-induced cytidine deaminase (AID), helps in the process that changes an adult human cell into an induced pluripotent stem cell (iPS cell). These iPS cells can then be developed into any kind of cell needed to therapeutically restore tissues and organs...
Burnt sugar derivative reduces muscle wasting in fly and mouse muscular dystrophy
Date: Aug-05-2013A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in a mouse model of Duchenne muscular dystrophy. The findings were published Aug. 1, in the journal Skeletal Muscle. Morayma Reyes, professor of pathology and laboratory medicine, and Hannele Ruohola-Baker, professor of biochemistry and associate director of the Institute for Stem Cell and Regenerative Medicine, headed the University of Washington team that made the discovery...
Scientists discover new type of protein modification, may play role in cancer and diabetes
Date: Aug-05-2013Scientists at The Scripps Research Institute (TSRI) have discovered a new type of chemical modification that affects numerous proteins within mammalian cells. The modification appears to work as a regulator of important cellular processes including the metabolism of glucose. Further study of this modification could provide insights into the causes of diabetes, cancer and other disorders...
Re-learning how to see: researchers find crucial on-off switch in visual development
Date: Aug-05-2013A new discovery by a University of Maryland-led research team offers hope for treating "lazy eye" and other serious visual problems that are usually permanent unless they are corrected in early childhood. Amblyopia afflicts about three percent of the population, and is a widespread cause of vision loss in children. It occurs when both eyes are structurally normal, but mismatched - either misaligned, or differently focused, or unequally receptive to visual stimuli because of an obstruction such as a cataract in one eye...
Blocking key enzyme in cancer cells could lead to new therapy
Date: Aug-05-2013Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer - and they believe it could be exploited as a target to develop new treatment strategies. An enzyme that metabolizes the glucose needed for tumor growth is found in high concentrations in cancer cells, but in very few normal adult tissues...
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