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Novozymes Biopharma's Hyasis® increases drug release of tramadol hydrochloride from 1.9 to 7.5 hours
Date: Jul-22-2013Novozymes Biopharma, part of Novozymes A/S, a world leader in bioinnovation, today announced the release of new findings concerning the effect of Bacillus-derived Hyaluronic Acid (HA) on the drug release of tramadol hydrochloride. The new research is to be presented as a scientific poster at the 2013 Controlled Release Society (CRS) annual meeting, July 21-24, Hawaii, USA...
Half a million UK cancer survivors faced with disability and poor health, UK
Date: Jul-22-2013At least one in four people living with cancer - over 500,000 in the UK[1] - experience a wide range of long-term debilitating health conditions caused by their cancer, according to a new report by Macmillan Cancer Support. The Cured - but at what cost? report - which looks at the long-term consequences of cancer and its treatment - shows that cancer survivors have an increased risk of other serious conditions. Women living with or after breast cancer are almost twice as likely to get heart failure compared to those who have not had it, while men who have had prostate cancer are 2...
Proteomics can improve breast cancer treatment
Date: Jul-22-2013Researchers at Karolinska Institutet in Sweden have identified a protein that could help physicians decide what type of therapy patients with hormone driven breast cancer should go through. In a study, published in Nature Communications, they show that high levels of a protein called retinoic acid receptor alpha (RARA) in breast tumors can be linked to an insufficient response to the cancer drug tamoxifen. The findings are based on a novel proteomics technique, developed at the Science for Life Laboratory. About 80% of all breast cancer tumors depend on the female hormone estrogen to grow...
A compound in red grapes, including red wine, counteracts exercise benefits in older men
Date: Jul-22-2013In older men, a natural antioxidant compound found in red grapes and other plants -- called resveratrol -- blocks many of the cardiovascular benefits of exercise, according to research published today [22 July 2013] in The Journal of Physiology. Resveratrol has received widespread attention as a possible anti-aging compound and is now widely available as a dietary supplement; much has been made of its role in explaining the cardiovascular health benefits of red wine, and other foods...
Huge increase in hand hygiene compliance rates with electronic monitoring systems
Date: Jul-22-2013GOJO Industries, a leader in hand hygiene and skin health and inventors of PURELL® Hand Sanitizer, conducted an independent research study at the John Peter Smith Hospital in Fort Worth, Texas to determine the impact on hand hygiene compliance rates when the hospital hand hygiene program included an electronic compliance activity monitoring system. The compliance technology system used in the study was the GOJO SMARTLINK Activity Monitoring System. Results of the study were presented at the APIC 2013 Conference...
Identification of cellular channels vital for hearing
Date: Jul-22-2013Ending a 30-year search by scientists, researchers at Boston Children's Hospital have identified two proteins in the inner ear that are critical for hearing, which, when damaged by genetic mutations, cause a form of delayed, progressive hearing loss. Findings were published online by the journal Neuron. The mutations, affecting genes known as TMC1 and TMC2, were reported in 2011 by the laboratory of Jeffrey Holt, PhD, in the Department of Otolaryngology at Boston Children's. Until now, however, it wasn't clear what the genes do...
New approach to treating the most common heart valve disease in Western countries
Date: Jul-22-2013A study conducted by the team of Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute (MHI), has led to the discovery of a new approach to treat aortic valve stenosis through the administration of a compound that prevents valve deterioration and can even reverse the progression of the disease. A condition that is characterized by a narrowing of the aortic valve that affects approximately 150,000 Canadians, aortic valve stenosis is the most common type of heart valve disease in Western countries...
Psychological and behavioral symptoms delayed by early detection and treatment of Alzheimer's disease
Date: Jul-22-2013People with Alzheimer's disease are able to manage their everyday activities longer and they suffer from less psychological and behavioural symptoms if the diagnosis is made and treatment begun at a very early phase of the disease, indicates a recent study conducted at the University of Eastern Finland. The study followed people with Alzheimer's disease over a course of three years. The study participants were diagnosed either at the very mild or mild phase of the disease and treated within the standard healthcare system...
Recommended irradiation dose and time window of local x-ray for spinal cord injury
Date: Jul-22-2013The glial scar is the main inhibitor of axon regeneration and functional recovery in the central nervous system. Appropriate dose X-ray irradiation has been shown to inhibit the formation of glial cells, thereby promoting axonal regeneration. In addition, X-rays militate against the death and degeneration of neurons, and improve the recovery of locomotor function following spinal cord injury. However, the optimal treatment time window and dose of X-irradiation for spinal cord injury is still unknown. Prof...
Program may hold promise for reducing avoidable hospital readmissions
Date: Jul-22-2013Recent federal legislation imposes financial penalties on hospitals that experience excessive patient readmissions within 30 days. A new study published today in the Journal of Hospital Medicine looks at the potential of a program designed to improve the discharge process and prevent avoidable rehospitalizations...
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