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Study Shows Reduction In Blood Glucose With Investigational Compound Empagliflozin Used To Treat Adults With Type 2 Diabetes

Date: Jun-26-2013
Data presented at the American Diabetes Association 73rd Scientific Sessions® also showed statistically significant reductions in mean daily glucose and body weight in treated study subjects Boehringer Ingelheim and Eli Lilly and Company have announced results of two Phase III 24week clinical trials of the investigational compound empagliflozin* added to metformin with and without the addition of sulphonylurea, respectively, in people with Type 2 Diabetes (T2D)...

Trajenta® (Linagliptin): New Data On Safety And Efficacy In Type 2 Diabetes Patients With Moderate To Severe Renal Impairment

Date: Jun-26-2013
Data presented at the American Diabetes Association (ADA) 73rd Scientific Sessions® provides insights for use of Trajenta® (linagliptin) in adults with Type 2 Diabetes (T2D) with moderate to severe renal impairment Boehringer Ingelheim and Eli Lilly and CompanyÂ� have announced results from a new study that demonstrated linagliptin showed statistically significant reduction in blood glucose levels (HbA1C) in adult patients with Type 2 Diabetes (T2D) with moderate to severe renal impairment (RI), compared with those receiving placebo (12 weeks)...

'Out-Of-Body' Virtual Experience Could Help Social Anxiety

Date: Jun-26-2013
New virtual imaging technology could be used as part of therapy to help people get over social anxiety according to new research from the University of East Anglia (UEA). Research published today investigated for the first time whether people with social anxiety could benefit from seeing themselves interacting in social situations via video capture. The experiment gave participants the chance to experience social interaction in the safety of a virtual environment by seeing their own life-size image projected into specially scripted real-time video scenes...

Exotic Fish Study Sheds Light On How Our Nerves Protect Themselves

Date: Jun-26-2013
Fresh insights gained from a study of tropical fish could help our understanding of how the nervous system works. Researchers have uncovered vital clues in zebrafish brains about the way our bodies produce myelin, a fatty sheath that insulates and protects nerve fibres. Myelin is critical for allowing nerve impulses to be transmitted quickly, enabling us to carry out a range of everyday functions such as walking, speaking and seeing...

Longest-Ever Intervention Study Investigating Whether Weight Loss Reduces The Risk Of Heart Disease For Patients With Type 2 Diabetes

Date: Jun-26-2013
A landmark study investigating the long-term effects of weight loss on the risks of cardiovascular disease among patients with Type 2 diabetes has now concluded, with significant results published in the New England Journal of Medicine. Conducted at the University of Pittsburgh and at clinical facilities throughout the United States, the multicenter clinical trial investigated the effects of an intensive lifestyle intervention program, intended to achieve and maintain weight loss in overweight or obese people with Type 2 diabetes, on rates of cardiovascular disease...

Phase III Data Show Investigational Compound Empagliflozin Reduced Blood Glucose In Adults With Type 2 Diabetes Treated With Basal Insulin

Date: Jun-26-2013
Data presented at the American Diabetes Association 73rd Scientific Sessions® also showed reduction in required insulin dose in treated study subjects Boehringer Ingelheim and Eli Lilly and Company have announced results of a 78week Phase III clinical trial of the investigational compound empagliflozin* as an addon to basal insulin in people with Type 2 Diabetes (T2D)...

Subtle Abnormalities Predict Which Older Adults Will Have Faster Decline In Visual Acuity

Date: Jun-26-2013
Sophisticated new optical quality metrics can identify older adults likely to have more rapid age-related declines in vision, suggests a study, "Factors Accounting for the 4-Year Change in Acuity in Patients Between 50 and 80 Years", in the July issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The study by Darren E...

Breast Cancer Stem Cells Destroyed By Targeted Viral Therapy In Preclinical Experiments

Date: Jun-26-2013
A promising new treatment for breast cancer being developed at Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine (VIMM) has been shown in cell culture and in animal models to selectively kill cancer stem cells at the original tumor site and in distant metastases with no toxic effects on healthy cells, including normal stem cells. Cancer stem cells are critical to a cancer's ability to recur following conventional chemotherapies and radiation therapy because they can quickly multiply and establish new tumors that are often therapy resistant...

Researchers Report Success Blocking Type 1 Diabetes Progression Using Psoriasis Drug

Date: Jun-26-2013
Researchers have blocked the progression of type 1 diabetes among newly diagnosed patients using a drug originally sold to treat psoriasis, according to the results of a clinical trial reported Saturday at a scientific meeting in Chicago. In a multicenter trial of 49 patients, those receiving the drug alefacept were producing the same amount of insulin one year after diagnosis, while patients receiving a placebo injection were producing less, consistent with the deterioration that usually occurs after diagnosis with the disease...

Antimicrobial Copper For Infection Control: A Health Economics Assessment

Date: Jun-26-2013
A unique health economics assessment of copper's role in preventing healthcare-associated infections (HCAIs) is being presented this week at the WHO's International Conference on Prevention and Infection Control (ICPIC) in Geneva, demonstrating rapid payback on the capital investment...