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Improved PET Medical Image Analysis To Optimize Radiotherapy Treatments

Date: Jun-13-2013
Elena Prieto-Azkarate, a graduate in Telecommunications Engineering at the NUP/UPNA-Public University of Navarre and member of the Nuclear Medicine Service of the University College Hospital of Navarre, has implemented 12 algorithms to process medical images produced by means of PET (Positron Emission Tomography). As she points out in her PhD thesis, read at the NUP/UPNA, the results obtained are highly promising and this technique could be very useful indeed...

Genetic Predictor Of Response To Exposure Therapy Aids In Posttraumatic Stress Disorder Treatment

Date: Jun-13-2013
There is growing evidence that a gene variant that reduces the plasticity of the nervous system also modulates responses to treatments for mood and anxiety disorders. In this case, patients with posttraumatic stress disorder, or PTSD, with a less functional variant of the gene coding for brain-derived neurotrophic factor (BDNF), responded less well to exposure therapy. This gene has been implicated previously in treatment response. Basic science studies have convincingly shown that BDNF levels are an important modifier of the therapeutic effects of antidepressants in animal models...

Improved Radionuclide Drug Treatment Planning With 3D Patient Models And Quantification Of Therapeutic Dose

Date: Jun-13-2013
External beam radiation treatment has long been manipulated into the unique shape of patients' tumors for personalized cancer care. Technology providing a means of patient-specific radionuclide drug therapies has not been standardized, as it has been limited to software that requires oncologists to manually define the areas of tumors...

New Development In The Understanding Of Alzheimer's Pathology

Date: Jun-13-2013
Alzheimer's disease has been linked in many studies to amyloid plaque buildup in the brain, but new research is finding a common thread between amyloid burden and lower energy levels, or metabolism, of neurons in certain areas of the brain associated with Alzheimer's disease - even for people with no sign of cognitive decline. This is a new development in the understanding of Alzheimer's pathology, say neuroscientists unveiling the research at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting...

Anti-Nicotine Vaccination Leads To Disparity In Natural Immune Response

Date: Jun-13-2013
Researchers have yet again been sent back to the drawing board in the development of the much-sought-after vaccination for smokers, which would hypothetically inhibit the action of nicotine and its pleasure-producing chemical response in the brain...

Overeating And Weight Gain Contributing To Onset Of Diabetes Could Be Related To A Deficit In Reward Circuits In The Brain

Date: Jun-13-2013
Using positron emission tomography (PET) imaging of the brain, researchers have identified a sweet spot that operates in a disorderly way when simple sugars are introduced to people with insulin resistance, a precursor to type 2 diabetes. For those who have the metabolic syndrome, a sugar drink resulted in a lower-than-normal release of the chemical dopamine in a major pleasure center of the brain. This chemical response may be indicative of a deficient reward system, which could potentially be setting the stage for insulin resistance...

Patients With Tumors In Nerve- And Hormone-Sensitive Organs Live Years Longer Following Targeted Peptide Receptor Radionuclide Therapy

Date: Jun-13-2013
Peptide-receptor radionuclide therapy (PRRT) has been a subject of growing research on neuroendocrine tumors, which take up residence in a variety of organs replete with nerve cells that respond to hormone signaling. A countrywide study in Germany deemed PRRT treatment not only safe and effective but life-prolonging, according to a study unveiled during the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting. PRRT is a new and yet-to-be-approved treatment for patients with neuroendocrine tumors (NETs)...

In Gout Flare-Ups, The Big Toe Isn't The Biggest Culprit - Other Joints Tied To Higher Risk

Date: Jun-13-2013
The painful rheumatic condition gout is often associated with the big toe, but it turns out that patients at highest risk of further flare-ups are those whose gout first involved other joints, such as a knee or elbow, Mayo Clinic has found. The study is among several that Mayo researchers are presenting in Madrid at the European League Against Rheumatism's annual meeting...

Fingernail Research Could Drive Limb Regeneration

Date: Jun-13-2013
Researchers have discovered the biological chain of events that enable mammals to regenerate a lost fingertip. The finding has huge potential and could drive the development of future therapies to regenerate lost limbs. When a fingertip is lost, humans and other mammals are able to completely regenerate it. In fact, it only takes a couple of months before an amputated fingertip fully regenerates itself. The phenomenon has intrigued scientists for a long time. The study was published in the journal Nature and written by researchers at NYU Langone Medical Center...

Earlier Warning Of Coronary Disease Provided By Metabolic PET Imaging

Date: Jun-13-2013
Coronary artery disease (CAD) is one of the world's most prevalent and silent killers. Positron emission tomography (PET), which images miniscule abnormalities in cellular metabolism, can tip off clinicians about cardiac disasters waiting to happen - including sudden death from a heart attack - better than standard angiography, researchers revealed at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting...