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Obesity During Pregnancy Programs Offspring To Be Fat, But Legacy Can Be Overturned
Date: Jun-13-2013Scientists in Sydney, Australia, have discovered that obesity and type 2 diabetes in pregnancy can program children to develop metabolic problems later in life. The good news is, this legacy is not set in stone - if children of obese mothers are careful about what they eat, it can be overturned. The study, carried out by scientists at the Victor Chang Cardiac Research Institute, is published in the June edition of the journal Epigenetics. By using genetically identical mice as a model, the team investigated the effects of having a mother with obesity and type 2 diabetes...
Pediatric PET Imaging Of Gliomas Gets A Boost With An Easier-To-Manufacture Imaging Agent
Date: Jun-13-2013A relatively new weapon in the fight against childhood brain cancer has emerged that improves upon standard magnetic resonance imaging (MRI) by providing information about tumor metabolism and extent of cancer in children diagnosed with glioma, a growth caused by the abnormal division of glial cells in the brain, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting. Brain cancer imaging is often conducted with conventional MRI, but there are some limitations to this imaging technique...
Identifying Diabetic Foot Infection And Ruling Out A Non-Infectious Complication That Develops In Nerve-Damaged Joints
Date: Jun-13-2013Researchers are kick-starting better diabetic foot care and promoting reduced radiation dose with a new take on a hybrid molecular imaging technique. By targeting both bone cell activity and immune response and improving imaging data interpretation, doctors can better distinguish diabetic foot infection from another common foot condition that often requires an additional bone-marrow scan for definitive diagnosis, say researchers presenting a study at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting...
Magnetic Resonance-Based Wearable Technology Accounts For Patient Movement For Clearer Data Reconstruction
Date: Jun-13-2013One of the biggest hurdles of hybrid positron emission tomography and magnetic resonance (PET/MR) imaging is the prevalence of motion artifacts - blurring and ghostly visual anomalies caused by patient motion on the table during imaging. An MR technology has now been designed for PET/MR that employs tiny radiofrequency solenoids - metal coils integrated into hardware placed on the body - to track motion from those who do not or cannot stay put...
SPECT/MR Molecular Imaging System Makes Its Debut
Date: Jun-13-2013The Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting marks the unveiling of the successful application of a new preclinical hybrid molecular imaging system - single photon emission tomography and magnetic resonance (SPECT/MR) - which has exceptional molecular imaging capabilities in terms of potential preclinical and clinical applications, technological advancement at a lower cost, and reduction of patient exposure to ionizing radiation...
Non-Hodgkin Lymphoma Survival Predicted By Dose Analysis
Date: Jun-13-2013Outcomes can be bleak for non-Hodgkin lymphoma (NHL), a cancer that develops in the white blood cells of the immune system. Accurate estimation of radiation absorbed dose in radioimmunotherapy (RIT) based on state-of-the-art 3D imaging could lead to more personalized and effective treatments to improve patients' chances of living longer without progression of their cancer, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting...
Cardiac MRI Use Reduces Adverse Events For Patients With Acute Chest Pain
Date: Jun-13-2013Wake Forest Baptist Medical Center doctors have found that using stress cardiac magnetic resonance (CMR) imaging in an Emergency Department observation unit to care for patients with acute chest pain is a win-win - for the patient and the institution. In a small, single-center clinical trial, Chadwick Miller, M.D., M.S., and colleagues found that evaluating older, more complex patients in the observation unit with stress cardiac MRI, as opposed to usual inpatient care, reduced hospital readmissions, coronary revascularization procedures and the need for additional cardiac testing...
Rapamycin Given Late In Life Reverses Age-Related Heart Disease In Mice
Date: Jun-13-2013Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months. The research, led by a team of scientists at the Buck Institute for Research on Aging, shows how rapamycin impacts mammalian tissues, providing functional insights and possible benefits for a drug that has been shown to extend the lifespan of mice as much as 14 percent. There are implications for human health in the research appearing online in Aging Cell: heart disease is the leading cause of death in the U.S...
Side Effects Of Radiation To Treat Prostate Cancer Reduced By Biodegradable Implant
Date: Jun-13-2013Several years ago, Virginia Commonwealth University Massey Cancer Center became the first center in the United States to test an Israeli-invented device designed to increase the space between the prostate and the rectum in prostate cancer patients undergoing radiation therapy. Now, results from the international Phase I clinical trial show that the device has the potential to significantly reduce rectal injury, a side effect caused by unwanted radiation exposure that can leave men with compromised bowel function following treatment...
Malignant Cells Not Directly Targeted By Hormonal Treatment For Endometrial Cancer
Date: Jun-13-2013Progesterone, a female hormone that can be used as a therapy for endometrial cancer, eliminates tumor cells indirectly by binding to its receptor in stromal or connective tissue cells residing in the tumor microenvironment, according to a study from the G.O. Discovery Lab team and collaborators at UCLA. Like tumors of the breast and prostate, endometrial cancer is regulated by hormones. Unlike therapies for breast and prostate cancer, where drugs are given to block hormone signaling, in therapy for endometrial cancer progesterone is given to stimulate its hormone receptor...
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