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Novel Targeted Therapies With Fewer Harmful Side Effects
Date: Jun-12-2013Conventional treatments for diseases such as cancer can carry harmful side effects - and the primary reason is that such treatments are not targeted specifically to the cells of the body where they're needed. What if drugs for cancer, cardiovascular disease, and other diseases can be targeted specifically and only to cells that need the medicine, and leave normal tissues untouched? A new study involving Sanford-Burnham Medical Research Institute's Erkki Ruoslahti, M.D., Ph.D., contributing to work by Samir Mitragotri, Ph.D...
Increased Use Of Split Liver Transplants For Young Children Could Significantly Increase Pediatric Organ Donor Pool
Date: Jun-12-2013A new study shows that when a liver from a deceased adult or adolescent donor is split into two separate portions for transplantation - with the smaller portion going to a young child and the larger to an adult - the smaller portion used for the child will last just as long as if the child had received a whole organ from a donor close to his size...
Providing Mental Health Care Lowers Arrest Rates, Saves Money
Date: Jun-12-2013Research from North Carolina State University, the Research Triangle Institute (RTI) and the University of South Florida shows that outpatient treatment of mental illness significantly reduces arrest rates for people with mental health problems and saves taxpayers money. "This study shows that providing mental health care is not only in the best interest of people with mental illness, but in the best interests of society," says Dr. Sarah Desmarais, an assistant professor of psychology at NC State and co-author of a paper describing the research...
Blood Pressure Is Higher At Night Than Originally Thought
Date: Jun-12-2013Blood pressure measured near the heart is significantly higher during sleep than originally thought, according to a new technology developed by scientists at UCL. Blood pressure at night is an important predictor of both stroke and heart disease, with previous research suggesting that blood pressure calculated via the arm decreases at night during sleep. But the current study reveals that night-time reduction in blood pressure may be less significant than originally thought...
Over-Confidence May Come Before A Fall
Date: Jun-12-2013Overprecision - excessive confidence in the accuracy of our beliefs - can have profound consequences, inflating investors' valuation of their investments, leading physicians to gravitate too quickly to a diagnosis, even making people intolerant of dissenting views. Now, new research confirms that overprecision is a common and robust form of overconfidence driven, at least in part, by excessive certainty in the accuracy of our judgments...
Risk Factors For Suicide Mapped
Date: Jun-12-2013A landmark study of the Swedish population has given a clearer picture of important risk factors for suicide. The study, a collaboration between Lund University in Sweden and Stanford University, showed that the rate of suicide among men is almost three times that of women. Being young, single and having a low level of education were stronger risk factors for suicide among men, while mental illness was a stronger risk factor among women. Unemployment was the strongest social risk factor among women, whereas being single was the strongest among men...
Obstructive Sleep Apnea Raises Sudden Cardiac Death Risk
Date: Jun-12-2013People with moderate obstructive sleep apnea have a higher risk of sudden cardiac death, researchers reported in the Journal of the American College of Cardiology. Sudden cardiac death is when the heart unexpectedly stops functioning completely and the person dies. It is the main cause of natural death in the USA, causing approximately 325,000 adult deaths in the country every year. Half of all heart deaths are caused by sudden cardiac death...
Outlawing Psychoactive Drugs "Censors Science"
Date: Jun-12-2013Having laws making it illegal to possess cannabis, magic mushroom, MDMA (ecstasy) and other psychoactive drugs amounts to scientific censorship, researchers from Imperial College London and the University of North Carolina at Chapel Hill wrote in the journal Nature Reviews Neuroscience...
Master Regulator Discovered In Cancer Metastasis
Date: Jun-12-2013The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance. However, cancer cells learn how to release themselves from these bonds and invade surrounding tissues, blood, and the lymphatic system...
Optical Antennas Inside Nano-Boxes Catch Individual Molecules In A Million
Date: Jun-12-2013A single cell in our body is composed of thousands of millions of different biomolecules that work together in an extremely well-coordinated way. Likewise, many biological and biochemical reactions occur only if molecules are present at very high concentrations. Understanding how all these molecules interact with each other is key to advancing our knowledge in molecular and cell biology. This knowledge is of central and fundamental importance in the quest for the detection of the earliest stages of many human diseases...
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