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Avandia (rosiglitazone) Does Not Raise Heart Attack Risk, Study
Date: Jun-07-2013There is not a higher risk of heart attack and cardiovascular events in patients who take controversial type 2 drug Avandia (rosiglitazone), researchers at the Duke Clinical Research Institute (DCRI) reported after carrying out a re-analysis of data from a pivotal study. The DCRI researchers re-assessed the original findings of RECORD, a study that drew criticism from an 2010 FDA advisory panel. Yesterday, an FDA advisory panel recommended loosening the restrictions on Avandia...
OCD Behavior In Mice Blocked Completely
Date: Jun-07-2013MIT neuroscientists have managed to block compulsive behavior in mice by activating a brain circuit that controls compulsive behavior. The finding could help drive the development of better treatment for obsessive-compulsive disorder (OCD) and Tourette's syndrome. Close to 1 percent of American adults have OCD and treatment usually involves a combination of therapy and medication (involving antianxiety drugs or antidepressants). Some people who don't respond to those treatment options undergo brain stimulation, which delivers electrical impulses in the brain...
Restrictions On Avandia (Rosiglitazone) Should Be Loosened, Says FDA Panel
Date: Jun-07-2013Most of the 26-member advisory FDA panel voted to loosen the restrictions which were placed on GSK's diabetes drug Avandia (rosiglitazone) in 2010 because of concerns it might raise the risk of heart attacks and death from cardiovascular causes. Seven panel members voted to remove all the restrictions, stating that the evidence for heart attack risk was not compelling, while five voted to leave the restrictions as they are. Thirteen voted to loosen the restrictions, e.g. not requiring patients to sign an informed consent form or to register...
Down's Syndrome Testing Can Be Earlier And More Reliable Say Researchers
Date: Jun-07-2013A new study reported this week shows UK researchers have developed a more reliable non-invasive test for Down's syndrome during the first three months of pregnancy. Writing in the 7 June online issue of Ultrasound in Obstetrics & Gynecology, Kypros Nicolaides of King's College London, and colleagues, suggest the test, which analyzes the baby's DNA in the expectant mother's blood, is superior to currently available non-invasive ways of screening for Down's syndrome. In the UK every year, around 750 babies are born with Down's syndrome...
Stem Cell Congress - World Class Speakers Announced, 4-5 November 2013, London
Date: Jun-07-2013Experts predict that the stem cell industry will be worth over $5 billion by 2014, reflecting the enormous potential of stem cell technologies in the pharmaceutical industry. In the light of this Oxford Global Conferences are proud to present our Stem Cell Congress, to be held on the 4th & 5th November 2013 at the Copthorne Tara, London Kensington. The congress has confirmed world class speakers within the stem cell field...
30 Million To Remain Uninsured Under Obamacare: New State-By-State Estimates At Health Affairs Blog
Date: Jun-07-2013Harvard and CUNY researchers say 4.9 million Texans and 3.7 million Californians will still be uninsured in 2016 A study released recently on the Health Affairs blog finds that between 29.8 million and 31.0 million people will remain uninsured after the implementation of the Affordable Care Act in 2016 and breaks down those figures by state. The research team from Harvard Medical School and the City University of New York School of Public Health projects that the demographic composition of today's uninsured population will change little under Obamacare...
Dementia Rates Double In China, Study Finds
Date: Jun-07-2013The number of people in China living with dementia has more than doubled over the past 20 years, a study has shown. Disease rates are increasing faster than previously thought so much so that caring for dementia patients will soon cost health services more than tackling heart disease and cancer combined, experts have warned. Latest figures show that in 1990, 3.68 million people had dementia in China and by 2010 this number had risen to 9.2 million...
Bioengineered Vein Implanted Into Kidney Dialysis Patient
Date: Jun-07-2013In a first-of-its-kind operation in the United States, a team of doctors at Duke University Hospital helped create a bioengineered blood vessel and transplanted it into the arm of a patient with end-stage kidney disease. The procedure, the first U.S. clinical trial to test the safety and effectiveness of the bioengineered blood vessel, is a milestone in the field of tissue engineering. The new vein is an off-the-shelf, human cell-based product with no biological properties that would cause organ rejection...
Reversal Cells May Tip The Balance Between Bone Formation And Resorption In Health And Disease
Date: Jun-07-2013Investigators Report on a Possible "Missing Link" in The American Journal of Pathology By analyzing biopsy specimens from patients with postmenopausal osteoporosis and primary hyperparathyroidism, investigators have begun to pay increasing attention to "reversal cells," which prepare for bone formation during bone remodeling. The hope is that these reversal cells will become critical therapeutic targets that may someday prevent osteoporosis and other bone disorders. This study is published in the May 2013 issue of The American Journal of Pathology...
Insight Into Cardiovascular Disease, The UK's Biggest Killer
Date: Jun-07-2013Cardiovascular disease is the leading cause of death in the UK, accounting for a third of all fatalities through illnesses such as stroke and heart disease. The risk increases with age which is why researchers at Lancaster University have been studying how the cardiovascular system alters as we grow older. Blood flow and other cardiovascular signals from 200 people of all ages were recorded and analysed using novel methods from physics and mathematics, which revealed the subtle changes which occur with age...
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