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Hospital Patients On Antibiotics Benefit From Probiotics
Date: Jun-07-2013Patients in hospital who are on antibiotics may benefit from taking probiotics, according to researchers at St. Michael's Hospital. Dr. Reena Pattani led a literature review that looked at the effectiveness of probiotics, live bacteria that can take up residence in digestive tracts, in treating common side effects of antibiotics, such as antibiotic-associated diarrhea and life-threatening side effects such as Clostridium difficile infection. "These two conditions are associated with high morbidity, mortality and health care costs," said Dr. Pattani, an internal medicine resident...
Changes In The Aging Brain Affect Hand-Eye Coordination
Date: Jun-07-2013For many older adults, the aging process seems to go hand-in-hand with an annoying increase in clumsiness - difficulties dialing a phone, fumbling with keys in a lock or knocking over the occasional wine glass while reaching for a salt shaker. While it's easy to see these failings as a normal consequence of age-related breakdowns in agility, vision and other physical abilities, new research from Washington University in St...
Many Children With Duchenne Muscular Dystrophy Could Benefit From Genetic Editing
Date: Jun-07-2013Using a novel genetic 'editing' technique, Duke University biomedical engineers have been able to repair a defect responsible for one of the most common inherited disorders, Duchenne muscular dystrophy, in cell samples from Duchenne patients. Instead of the common gene therapy approach of adding new genetic material to "override" the faulty gene, the Duke scientists have developed a way to change the existing mutated gene responsible for the disorder into a normally functioning gene...
Screening For Frailty Could Prevent Deaths
Date: Jun-07-2013Everyone older than 70 should be checked for frailty, a condition that is both easily treated and potentially deadly, according to an article by representatives from six major international and U.S. medical organizations. "Frailty is extraordinarily common, affecting between 5 and 10 percent of those who are older than 70. Women are more likely to be frail than men," said John Morley, M.D., director of the division of geriatric medicine at Saint Louis University and lead author of the article that appeared in the June edition of the JAMDA...
Biomarker Identification May Lead To New Noninvasive Test For Colorectal Cancer Detection
Date: Jun-07-2013Serum DNA Analysis Allows Detection of Early Disease, Say Researchers in The Journal of Molecular Diagnostics The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera. This test detected 87% of all stages of colorectal cancer cases (sensitivity) without significant difference between early and advanced stages, while correctly identifying 95% of disease-free patients (specificity)...
Update On 'Designer Stimulants'
Date: Jun-07-2013The last few years have seen the emergence of a new drug problem in so-called "bath salts" - actually "designer stimulants," packaged and sold in ways that skirt drug laws. A review and update on these designer drugs is presented in the June Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. Recent high-profile incidents have drawn attention to "bath salts" as a new and potentially hazardous type of recreational drug...
Revised Clinical Practice Guideline On The Treatment Of Osteoarthritis Of The Knee
Date: Jun-07-2013The American Academy of Orthopaedic Surgeons (AAOS) recently released its revised clinical practice guideline (CPG) on the treatment of osteoarthritis of the knee, addressing two key changes. Most of the remaining recommendations provided in the 2009 CPG go unchanged. CPGs are not meant to be stand-alone documents, but rather serve as a point of reference and educational tool for both primary care physicians and orthopaedic surgeons. The original guideline, as well as this revised version, was developed to include only treatments which are less invasive than knee replacement surgery...
Link Discovered Between Genetic Mutation Inherited From Father's Side And Early Puberty
Date: Jun-07-2013Reaching puberty at an unusually early age can have adverse effects on social behavior and psychological development, as well as physical effects, including short stature, and lifelong health risks, such as diabetes, breast cancer and heart disease. Researchers at Brigham and Women's Hospital (BWH), in a multi-institutional collaboration with Boston Children's Hospital, the Broad Institute, and the University of Sao Paulo, Brazil, have identified that a genetic mutation leads to a type of premature puberty, known as central precocious puberty...
Diabetes And Heart Health Matter To Your Brain
Date: Jun-07-2013People suffering from type 2 diabetes and cardiovascular disease (CVD) are at an increased risk of cognitive decline, according to a new study from Wake Forest Baptist Medical Center. Lead author Christina E. Hugenschmidt, Ph.D., an instructor of gerontology and geriatric medicine at Wake Forest Baptist, said the results from the Diabetes Heart Study-Mind (DHS-Mind) suggest that CVD is playing a role in cognition problems before it is clinically apparent in patients. The research appears online ahead of print in the Journal of Diabetes and Its Complications...
Post-Traumatic Stress-Like Symptoms Prevented In Mice
Date: Jun-07-2013When injected into mice immediately following a traumatic event, a new drug prevents the animals from developing memory problems and increased anxiety that are indicative of post-traumatic stress disorder (PTSD). Howard Hughes Medical Institute scientists utilized mouse studies to suggest that a receptor called Oprl1 is altered in mice with PTSD-like symptoms. They then worked with a group at the Scripps Research Institute who had previously developed the Oprl1-targeted drug to examine its effects on fear memory modulation...
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