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Molecular Cousin To Ketamine Rapidly Lifts Depression Without Side Effects
Date: Jun-03-2013GLYX-13, a molecular cousin to ketamine, induces similar antidepressant results without the street drug side effects, reported a study funded by the National Institute of Mental Health (NIMH) that was published last month in Neuropsychopharmacology. Background Major depression affects about 10 percent of the adult population and is the second leading cause of disability in U.S. adults, according to the World Health Organization...
Billions Worldwide Suffer From Major Tooth Decay
Date: Jun-03-2013Billions of people across the globe are suffering from major untreated dental problems, according to a new report led by Professor Wagner Marcenes of Queen Mary, University of London, published in the Journal of Dental Research. Professor Marcenes of the Institute of Dentistry at Queen Mary led an international research team investigating oral health as part of the Global Burden of Disease (GBD) 2010 study. The report shows that oral conditions affect as many as 3.9bn people worldwide - over half the total population...
Kidney Disease Often Leads To Heart Attack Because Uremic Toxins Are Not Removed By Hemodialysis
Date: Jun-03-2013Patients with advanced kidney disease who are undergoing hemodialysis are known to be highly susceptible to heart attacks and other cardiovascular complications, and now scientists likely know why. New research findings published in the Journal of Leukocyte Biology show that uremic toxins, which are not removed by hemodialysis, increase heart attack risk. The same scientists also have found what can reduce this risk: an oral adsorbent called "AST-120...
Insight Into Key Protein Linked To Development Of Cancers And Neurodegenerative Disorders
Date: Jun-03-2013Virginia Commonwealth University researchers studying a key molecular player called Hsp70 that is responsible for protein homeostasis have uncovered how it binds together with another molecule responsible for intracellular energy transfer to enhance its overall activity and efficiency - details that have previously not been well understood. Heat shock proteins, particularly the 70-kilodalton heat shock proteins, Hsp70, are important for cellular processes such as protein folding and protecting cells from stress. It is also involved with protein assembly, degradation and transport...
Stimulating The Immune System To Fight Brain Tumors
Date: Jun-03-2013Research at Lund University in Sweden gives hope that one of the most serious types of brain tumor, glioblastoma multiforme, could be fought by the patients' own immune system. The tumors are difficult to remove with surgery because the tumor cells grow into the surrounding healthy brain tissue. A patient with the disease therefore does not usually survive much longer than a year after the discovery of the tumor. The team has tested different ways of stimulating the immune system, suppressed by the tumor, with a 'vaccine'...
Novel Approach Identified For Creating Red Blood Cells, Platelets In Vitro
Date: Jun-03-2013A study led by Boston University School of Medicine has identified a novel approach to create an unlimited number of human red blood cells and platelets in vitro. In collaboration with Boston University School of Public Health (BUSPH) and Boston Medical Center (BMC), the researchers differentiated induced pluripotent stem (iPS) cells into these cell types, which are typically obtained through blood donations...
Rapid Diagnosis And Treatment Of Sepsis Following New Discovery
Date: Jun-03-2013Despite numerous advances in treating infections and disease, effective treatments for sepsis remain elusive. A new discovery published in the June 2013 issue of The FASEB Journal not only could help health care providers predict who is more and less likely to develop sepsis, but it also opens the doors to new therapies that actually address the root cause of the problem, rather than just managing the symptoms...
Specially Designed Nanoparticles Offer New Magnetically Targeted Gene Delivery Method
Date: Jun-03-2013Stent angioplasty saves lives, but there often are side effects and complications related to the procedure, such as arterial restenosis and thrombosis. In the June 2013 issue of The FASEB Journal, however, scientists report that they have discovered a new nanoparticle gene delivery method that may overcome current limitations of gene therapy vectors and prevent complications associated with the stenting procedure...
Inflammation Associated With Heart Surgery May Be Reduced By Omega-3 Fatty Acids
Date: Jun-03-2013Procedures like angioplasty, stenting and bypass surgery may save lives, but they also cause excessive inflammation and scarring, which ultimately can lead to permanent disability and even death. A new research report appearing in The FASEB Journal, shows that naturally derived compounds from polyunsaturated fatty acids (omega-3s) may reduce the inflammation associated with these procedures to help arteries more fully and completely heal...
A Popular Source For Vaccination Information, Debate - Twitter
Date: Jun-03-2013Twitter is a popular source for receiving and sharing new information about vaccines, and also a basically reliable one, according to a study published in the June issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC). Researchers from the University of Texas at Austin analyzed 9,510 vaccination-related tweets from one week in January, 2012 to determine the most popular and influential messages...
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