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Developmental Outcomes In Children With Autism Predicted By Early Brain Responses To Words

Date: May-31-2013
The pattern of brain responses to words in 2-year-old children with autism spectrum disorder predicted the youngsters' linguistic, cognitive and adaptive skills at ages 4 and 6, according to a new study. The findings, published in the journal PLOS ONE, are among the first to demonstrate that a brain marker can predict future abilities in children with autism...

Broad Protection To Pandemic Flu Strains, Including 1918 Flu, Provided By Gene Therapy In Mouse Model

Date: May-31-2013
Researchers at the Perelman School of Medicine, University of Pennsylvania have developed a new gene therapy to thwart a potential influenza pandemic. Specifically, investigators in the Gene Therapy Program, Department of Pathology and Laboratory Medicine, directed by James M. Wilson, MD, PhD, demonstrated that a single dose of an adeno-associated virus (AAV) expressing a broadly neutralizing flu antibody into the nasal passages of mice and ferrets gives them complete protection and substantial reductions in flu replication when exposed to lethal strains of H5N1 and H1N1 flu virus...

Randomized Clinical Trials In Radiation Oncology Clinical Practice Of Great Value

Date: May-31-2013
Cancer patients, physicians and insurers want to be sure that whatever therapy is recommended and provided to patients is based on evidence, preferably results from randomized clinical trials. But are there enough clinical trials data to provide this level of confidence? A University of North Carolina School of Medicine study says not necessarily. Radiation oncologists evaluated how often patients were seen in their clinic with medical decisions to be made that were not specifically addressed by randomized controlled trials...

Link Between Childhood Abuse And Food Addiction In Adult Women

Date: May-31-2013
Women who experienced severe physical or sexual abuse during childhood are much more likely to have a food addiction as adults than women who did not experience such abuse, according to a new study published in the journal Obesity. The study's findings provide valuable new information regarding potential causes and treatments for food addiction and obesity. National surveys indicate that more than a third of American women experienced some form of physical or sexual abuse before they reached 18 years of age...

Chemical Reaction Identified That Causes Alzheimer's Plaques To Grow Exponentially

Date: May-31-2013
Researchers at Lund University in Sweden have identified the molecular mechanism behind the transformation of one of the components in Alzheimer's disease. They identified the crucial step leading to formations that kill brain cells. Alzheimer's disease is associated with memory a loss and personality changes. It is still not known what causes the onset of the disease, but once started it cannot be stopped. The accumulation of plaques in the brain is widely considered a hallmark of the disease. The key discovery identified the chemical reaction that causes the plaques to grow exponentially...

Pioneering Imaging Technique To Track The Effects Of Next-Generation Nanomedicines On Patients

Date: May-31-2013
Professor Dr. M. N. V. Ravi Kumar and Dr. Dimitrios Lamprou, of the Strathclyde Institute of Pharmacy and Biomedical Sciences, believe an advanced form of atomic force microscopy, known as PeakForce QNM, could boost developments in the field of nanomedicines, the encapsulation of potent drugs in tiny particles measuring billionths of a meter in diameter. They described how this detailed imaging approach may also help scientists address growing concerns in the medical world around "nanotoxicology", the build-up of microscopic particles in people's tissues...

Active Commuting Influenced By Others

Date: May-31-2013
People who walk or bike to work are likely to influence their co-workers and partners to do the same, according to health researchers. "Social influences are important, specifically interpersonal influences, such as spouses and co-workers," said Melissa Bopp, assistant professor of kinesiology, Penn State. She emphasized that community and employers also significantly influence whether people choose to actively commute...

Just 12 Minutes A Week Of High-Intensity Training Improves Fitness In Inactive Men

Date: May-31-2013
It is a commonly held perception that getting in shape and staying there requires hard work and hours upon hours of training. New research shows the opposite - it seems that only four minutes of vigorous activity three times per week is enough to be fit and healthy. Regular training improves maximal oxygen uptake (VO2max), which is a well-established measure of physical fitness. However, just how much exercise, and how intense that exercise should be to deliver the biggest benefit remains to be defined...

Reducing Levels Of Ataxin-1 May Be The Answer In Neurodegenerative Disorders

Date: May-31-2013
In some neurodegenerative diseases, and specifically in a devastating inherited condition called spinocerebellar ataxia 1 (SCA1), the answer may not be an "all-or-nothing," said a collaboration of researchers from Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and the University of Minnesota in a report that appears online in the journal Nature. The problem might be solved with just a little less...

Blood Test May Predict Gestational Diabetes Risk Early In Pregnancy

Date: May-31-2013
Levels of a biomarker in a pregnant woman's blood can help physicians gauge her risk of developing gestational diabetes during the first trimester, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).. Gestational diabetes is a form of diabetes that can develop during pregnancy, often during the second trimester. The condition causes glucose levels in the bloodstream to be higher than normal. Early diagnosis and treatment can help the woman manage the condition...