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Treating Alzheimer's Disease - New Chemical Approach
Date: May-30-2013Scientists at the University of Liverpool and Callaghan Innovation in New Zealand have developed a new chemical approach to help harness the natural ability of complex sugars to treat Alzheimer's disease. The team used a new chemical method to produce a library of sugars, called heparan sulphates, which are known to control the formation of the proteins in the brain that cause memory loss. Heparan sulphates are found in nearly every cell of the body, and are similar to the natural blood-thinning drug, heparin...
Drug Reps Concentrate On Benefits Of Drugs, Rarely Tell Physicians About The Side Effects
Date: May-30-2013An international study involving 255 physicians practising in Vancouver, Montreal, Sacramento and Toulouse found that physicians are not given enough information about the adverse effects of drugs during presentations made by medical sales representatives from pharmaceutical companies. And yet, these same physicians are willing to prescribe at least some of the presented drugs. Dr...
Imatinib Failure-Free Survival In Patients With Gastrointestinal Stromal Tumors
Date: May-30-2013Interim results of an EORTC intergroup trial have confirmed that adjuvant imatinib impacts short-term freedom from relapse in patients with localized, surgically resected, high/ intermediate-risk GIST. In the high-risk subgroup, a non-statistically significant trend in favor of the adjuvant arm was observed in terms of Imatinib failure-free survival...
Rationale For Use Of Targeted Immunotherapy In Sarcomatoid Lung Carcinomas
Date: May-30-2013Sarcomatoid carcinomas of the lung include rare subtypes of poorly differentiated non-small-cell lung carcinomas of high grade and aggressive behavior. The biology of these neoplasms is poorly understood and these tumors are aggressive and resistant to chemotherapy and radiotherapy. The identification of actionable molecular targets for such infrequent and aggressive diseases is critical for design of new clinical trials. Programmed death-1 (PD-1) is a co-inhibitory inducible receptor present on T-cells and macrophages...
NHS Profits From Pregnancy Labeled "Unacceptable"
Date: May-30-2013Trusted organizations, including the NHS and some UK royal colleges, profit by selling commercial advertisers access to pregnant women through promotions like Bounty bags, which has been labeled "unacceptable" by GP Margaret McCartney in a new report. McCartney pointed out, in British Medical Journal (BMJ), that a commercial company was offered access to moms through adverts and editorial content in a magazine being established by the Royal College of Obstetricians and Gynaecologists, called "Baby and You" - which is intended to be given to pregnant women for free...
More Visits Made To The ER By Disabled Patients Who Can't Afford Their Meds
Date: May-30-2013Disabled Medicare patients under the age of 65 who don't take their prescription medications because of cost concerns are more likely to have at least one emergency department visit during a one-year period. The results of a new study are published online in Annals of Emergency Medicine ("The Relationship Between Emergency Department Use and Cost-Related Medication Nonadherence Among Medicare Beneficiaries")...
Scientists Pave The Way For Vaccine To Combat Devastating Avian Disease
Date: May-30-2013Recent reduction in the use of antibiotic growth promoters in animal feeds has resulted in a dramatic increase in the severe poultry disease - necrotic enteritis. New research suggests that the disease, which is costing the worldwide poultry industry an estimated 600 million pounds a year, could be prevented by immunisation with a vaccine that is being developed at the University of Exeter...
Artificial Sweeteners Affect Metabolism And Insulin Levels
Date: May-30-2013The artificial sweetener sucralose (Splenda®) is capable of changing the body's insulin response, researchers at Washington University School of Medicine reported in the journal Diabetes Care. The study included 17 severely obese people who didn't consume artificial sweeteners often and weren't diagnosed with diabetes. Splenda does have an effect First author M. Yanina Pepino, PhD, research assistant professor of medicine, said: "Our results indicate that this artificial sweetener is not inert - it does have an effect...
How Domestic Violence Can Affect Perinatal Mental Health
Date: May-30-2013Women who have mental health disorders around the time of birth are more likely to have previously experienced domestic violence, according to a study by UK researchers published in this week's PLOS Medicine. The researchers, led by Louise Howard from King's College London, found that high levels of symptoms of perinatal* depression, anxiety, and post-traumatic stress disorder were linked to having experienced domestic violence either during pregnancy, the past year, or over a woman's lifetime...
GlaxoSmithKline Acquires Developer Of Vaccine Platform Technologies
Date: May-30-2013Pharmaceutical giant GlaxoSmithKline (GSK) has just strengthened its vaccine business with the acquisition of Okairos AG, a developer of vaccine platform technologies, for 250 million euros (324 million US dollars). Okairos AG, based in Switzerland, developed a new technology which will play a crucial role in the development of new classes of therapeutic and new prophylactic vaccines. Therapeutic vaccines treat diseases, while prophylactic ones prevent them...
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