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Male 'Menopause' Accelerated By Heart Failure
Date: May-28-2013Heart failure accelerates the aging process and brings on early andropausal syndrome (AS), according to research presented at the Heart Failure Congress 2013. AS, also referred to as male 'menopause', was four times more common in men with heart failure. The Heart Failure Congress is the main annual meeting of the Heart Failure Association of the European Society of Cardiology and is being held 25-28 May in Lisbon, Portugal...
In The Search For Alzheimer's Drugs A New Strategy May Be Required
Date: May-28-2013In the search for medication against Alzheimer's disease, scientists have focused - among other factors - on drugs that can break down Amyloid beta (A-beta). After all, it is the accumulation of A-beta that causes the known plaques in the brains of Alzheimer's patients. Starting point for the formation of A-beta is APP. Alessia Soldano and Bassem Hassan (VIB/KU Leuven) were the first to unravel the function of APPL - the fruit-fly version of APP - in the brains of healthy fruit flies...
RELAX-AHF Shows First Positive Findings In HFpEF Patients
Date: May-28-2013Serelaxin may be more effective for relieving dyspnea in heart failure with preserved ejection fraction (HFpEF) than reduced (HFrEF) during the first 24 hours, according to results from RELAX-AHF presented in a late breaking trial at the Heart Failure Congress 2013. Results were also presented from VIVIDD, the first trial of the anti-diabetes drug vildagliptin in patients with heart failure. The Heart Failure Congress is the main annual meeting of the Heart Failure Association of the European Society of Cardiology and is being held 25-28 May in Lisbon, Portugal...
Boosting Body's Natural Killers May Be The Way Forward For Fighting Flu
Date: May-28-2013A known difficulty in fighting influenza (flu) is the ability of the flu viruses to mutate and thus evade various medications that were previously found to be effective. Researchers at the Hebrew University of Jerusalem have shown recently that another, more promising, approach is to focus on improving drugs that boost the body's natural flu killer system. Emergence of new influenza strains, such as the recent avian influenza (H5N1) and swine influenza (H1N1 2009), can lead to the emergence of severe pandemics that pose a major threat to the entire world population...
EGFR Prevents Maturation Of Cancer-Fighting MiRNAs When Oxygen Is Short
Date: May-28-2013Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs (miRNAs) before it's dissolved, researchers reported in an early online publication at Nature. Under conditions of oxygen starvation often encountered by tumors, the epidermal growth factor receptor (EGFR) gums up the cell's miRNA-processing machinery, an international team led by scientists at The University of Texas MD Anderson Cancer Center discovered...
Neuron Formation Discovery Could Explain Cause Of Infantile Amnesia
Date: May-28-2013New research shows that formation of new neurons in the hippocampus - a brain region known for its importance in learning and remembering - could cause forgetting of old memories by causing a reorganization of existing brain circuits. Drs. Paul Frankland and Sheena Josselyn, both from the Hospital for Sick Children in Toronto, argue this reorganization could have the positive effect of clearing old memories, reducing interference and thereby increasing capacity for new learning...
More Child Poisonings Following Marijuana Legislation, Colorado
Date: May-28-2013More children are ending up at hospital emergency departments after unintentionally ingesting marijuana following the modification of drug enforcements laws for marijuana possession in Colorado, says a new report published in JAMA Pediatrics. Several U.S. states and Washington D.C. have passed laws decriminalizing medical marijuana. In Washington and Colorado laws have been amended to legalize the recreational use of marijuana. In 2009, federal prosecutors were told by the Justice Department not to arrest medical marijuana users and suppliers who were complying to state legislation...
Blood Transfusions Are Overused During Common Heart Surgery
Date: May-28-2013According to a new study published in The Lancet, blood transfusions are still being overused during common heart surgery even though there is compelling evidence demonstrating the dangers of unnecessary blood transfusions...
Huge Congenital Heart Disease Advance - Step Closer To Understanding Genetic Cause
Date: May-28-2013Researchers in the U.K have identified a new gene linked to the development of congenital heart disease (CHD) among newborn babies through large-scale sequencing analysis. The finding will help experts improve their understanding of this most common type of birth defect. The study, published in Nature Genetics, was led by Professor Bernard Keavney, from The University of Manchester and Newcastle University and included researchers from various other UK universities...
Huntington's Disease Breakthrough
Date: May-28-2013Researchers at Lund University have succeeded in preventing very early symptoms of Huntington's disease, depression and anxiety, by deactivating the mutated huntingtin protein in the brains of mice. "We are the first to show that it is possible to prevent the depression symptoms of Huntington's disease by deactivating the diseased protein in nerve cell populations in the hypothalamus in the brain. This is hugely exciting and bears out our previous hypotheses", explains �sa Petersén, Associate Professor of Neuroscience at Lund University...
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