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Giving Children With Leukemia The Best Chance For Long-Term Survival With Minimal Toxic Side Effects
Date: May-27-2013Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online in Blood, the Journal of the American Society of Hematology (ASH)...
Autologous Cord Blood Successfully Treats Pediatric Cerebral Palsy
Date: May-27-2013Awoken from a persistent vegetative state Bochum's medics have succeeded in treating cerebral palsy with autologous cord blood. Following a cardiac arrest with severe brain damage, a 2.5 year old boy had been in a persistent vegetative state - with minimal chances of survival. Just two months after treatment with the cord blood containing stem cells, the symptoms improved significantly; over the following months, the child learned to speak simple sentences and to move...
Common Childhood Asthma Unconnected To Allergens Or Inflammation
Date: May-27-2013Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center and SUNY Downstate Medical Center has revealed the roots of a common type of childhood asthma, showing that it is very different from other asthma cases...
In Children With Temporal Lobe Epilepsy Depression Is Common
Date: May-27-2013A new study determined that children and adolescents with seizures involving the temporal lobe are likely to have clinically significant behavioral problems and psychiatric illness, especially depression. Findings published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy (ILAE), highlight the importance of routine psychiatric evaluation for pediatric epilepsy patients - particularly for those who do not respond to anti-seizure medications and require epilepsy surgery...
Non-Invasive Unique Method To Define In The Whole Brain The Regions Involved In Epileptic Discharges
Date: May-27-2013New techniques in imaging of brain activity developed by Jean Gotman, from McGill University's Montreal Neurological Institute, and his colleagues lead to improved treatment of patients suffering from epilepsy. The combination of electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI) leads to more precise localization of the areas generating epileptic seizures, giving neurosurgeons a better understanding of the optimal ways of intervention, if appropriate...
Networks Of Neurons Identified In The Brain That Are Disrupted In Psychiatric Disease
Date: May-27-2013Studying the networks of connections in the brains of people affected by schizophrenia, bipolar disease or depression has allowed Dr. Peter Williamson, from Western University, to gain a better understanding of the biological basis of these important diseases. Dr. Williamson and colleagues have shown that different networks, found specifically in humans, are disrupted in different psychiatric diseases. These results were presented at the 2013 Canadian Neuroscience Meeting, the annual meeting of the Canadian Association for Neuroscience - Association Canadienne des Neurosciences (CAN-ACN)...
Lifestyle That Is Heart Healthy May Also Cut Kidney Disease Patients' Risk Of Kidney Failure, Prolong Their Lives
Date: May-27-2013Maintaining a heart healthy lifestyle may also help protect chronic kidney disease patients from developing kidney failure and dying prematurely, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that patients with kidney disease should be encouraged to improve their heart health. Poor kidney health puts people at risk of developing heart problems, but it's unclear whether the opposite is true...
Genetic Underpinnings Of Diabetes Can Vary Based On Ethnic Background
Date: May-27-2013Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine. The researchers reanalyzed disease data to demonstrate that the physiological pathways to diabetes vary between Africa and East Asia and that those differences are reflected in part by genetic differences. The studies were published online simultaneously in the journals PLoS Genetics and Diabetes Care...
Breast Cancer Advance That Turns Previous Thinking On Its Head
Date: May-27-2013Scientists at the University of East Anglia have made an advance in breast cancer research which shows how some enzymes released by cancerous cells could have a protective function. New research published in the Journal of Biological Chemistry reveals that an enzyme called MMP-8 (matrix metalloproteinase-8) could be acting as a locator to the immune system, which then becomes activated to attack tumours. It was originally thought that the production of MMPs by breast cancer cells worked to promote cancer growth...
Economic Incentives Increase Blood Donations Without Negative Consequences
Date: May-27-2013Canada and other countries should reassess guidelines that prohibit offering economic incentives such as gift cards to potential blood donors, says a study from the University of Toronto Mississauga (UTM). "Blood donation guidelines recommended by the World Health Organization (WHO) and many blood collection agencies are largely based on research that assessed only what study participants said they would do - not their observed behaviour when donating blood," says Nicola Lacetera, Assistant Professor in UTM's Department of Management. "These are two very different things...
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