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As Proof Of Principle, Technique Finds Antibody That Mimics Key Hormone For Blood Clotting

Date: May-27-2013
Scientists at The Scripps Research Institute (TSRI) have devised a powerful new technique for finding antibodies that have a desired biological effect. Antibodies, which can bind to billions of distinct targets, are already used in many of the world's best-selling medicines, diagnostics and laboratory reagents. The newly reported technique should greatly speed the process of discovering such products. "For the first time, we have a selection method whose power matches the vast diversity of the antibody repertoire," said Richard A...

News From 'Frontiers' May 23, 2013

Date: May-27-2013
Frontiers in Behavioral Neuroscience Spatial learning of female mice: a role of the mineralocorticoid receptor during stress and the estrous cycle In a stressful situation, rodents produce the stress hormone corticosterone. This helps the animal, because spatial learning is promoted when corticosterone binds to one of the stress hormone receptors (mineralocorticoid receptors) in the hippocampus, a region of the brain...

Tomatoes, Already More Healthy, Now More Tasty And Longer-Lasting

Date: May-27-2013
Tomatoes, said to be the world's most popular fruit, can be made both better-tasting and longer-lasting thanks to UK research with purple GM varieties. "Working with GM tomatoes that are different to normal fruit only by the addition of a specific compound, allows us to pinpoint exactly how to breed in valuable traits," said Professor Cathie Martin from the John Innes Centre. The research could also lead to GM varieties with better flavour, health and shelf life characteristics because even higher levels of the compounds can be achieved...

New Compounds Found To Curb Staph Infection

Date: May-27-2013
In an age when microbial pathogens are growing increasingly resistant to the conventional antibiotics used to tamp down infection, a team of Wisconsin scientists has synthesized a potent new class of compounds capable of curbing the bacteria that cause staph infections...

Link Between Depression, Telomere Enzyme, Aging And Chronic Disease

Date: May-27-2013
The first symptoms of major depression may be behavioral, but the common mental illness is based in biology - and not limited to the brain. In recent years some studies have linked major, long-term depression with life-threatening chronic disease and with earlier death, even after lifestyle risk factors have been taken into account. Now a research team led by Owen Wolkowitz, MD, professor of psychiatry at UC San Francisco, has found that within cells of the immune system, activity of an enzyme called telomerase is greater, on average, in untreated individuals with major depression...

Stroke-Related Disabilities May Be Improved By Regenerating Spinal Cord Fibers

Date: May-27-2013
A study by researchers at Henry Ford Hospital found "substantial evidence" that a regenerative process involving damaged nerve fibers in the spinal cord could hold the key to better functional recovery by most stroke victims. The findings may offer new hope to those who suffer stroke, the leading cause of long-term disability in adults. Although most stroke victims recover some ability to voluntarily use their hands and other body parts, about half are left with weakness on one side of their bodies, while a substantial number are permanently disabled...

High-profile Alzheimer's Study Remains Unconfirmed By Multiple Research Teams

Date: May-27-2013
Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science. Those results, presented online Feb. 9, 2012, suggested that the drug bexarotene (marketed as Targretin®) could rapidly reverse the buildup of beta amyloid plaques (Aβ) - a pathological hallmark of Alzheimer's disease - in the brains of mice...

War Support And PTSD; Time It Late In Negotiations; Courtship By Narcissists

Date: May-27-2013
Public level of support for war influences soldier PTSD Soldiers returning home from combat may be at a heightened risk for developing post-traumatic stress disorder if public support for a war effort is low, according to recent research. Social validation or invalidation shapes the level of distress soldiers feel from the act of killing, the researchers say...

Female Psychological Disorders Linked To Hormone Levels

Date: May-27-2013
Women are more susceptible to some of the psychological effects linked to stressful experiences at specific stages in their monthly menstrual cycle, scientists from University College London reported in Neurobiology of Learning and Memory. The authors believe common mental health problems that develop in women might be prevented if specific dates during the menstrual cycle are targeted. They say their study is the first to demonstrate a possible association between psychological vulnerability and a specific moment during the menstrual cycle - which in this case was ovulation...

Encouraging Results In The Development Of An Oral Vaccine Against Diarrhea

Date: May-27-2013
The University of Gothenburg Vaccine Research Institute (GUVAX) announces successful results in a placebo controlled phase I study of an oral, inactivated Escherichia coli diarrhea vaccine. Enterotoxigenic Escherichia coli (ETEC) bacteria are the primary cause of diarrhea in children living in low and middle income countries result in 400 million diarrheal episodes and approximately 300 000 deaths among children per year. ETEC is also the leading cause of illness among international travelers to developing countries...