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Monoclonal Antibody Appears Effective And Safe In Asthma Phase IIa Trial
Date: May-23-2013A novel approach to obstructing the runaway inflammatory response implicated in some types of asthma has shown promise in a Phase IIa clinical trial, according to U. S. researchers. Their research was presented at the American Thoracic Society 2013 International Conference and published simultaneously online in the New England Journal of Medicine...
Study Finds For First Time That Gym Class Reduces Probability Of Obesity
Date: May-23-2013Little is known about the effect of physical education (PE) on child weight, but a new study from Cornell University finds that increasing the amount of time that elementary schoolchildren spent in gym class reduces the probability of obesity. The study represents some of the first evidence of a causal effect of PE on youth obesity, and is forthcoming in the Journal of Health Economics. An early, online version of the study can be viewed here...
Researchers Hope To Recycle Kidneys To Help solve Donor Organ shortage
Date: May-23-2013Nearly 20 percent of kidneys that are recovered from deceased donors in the U.S. are refused for transplant due to factors ranging from scarring in small blood vessels of the kidney's filtering units to the organ going too long without blood or oxygen...
Searching For Biomarkers In Huntington's Disease
Date: May-23-2013While Huntington's disease (HD) is currently incurable, the HD research community anticipates that new disease-modifying therapies in development may slow or minimize disease progression. The success of HD research depends upon the identification of reliable and sensitive biomarkers to track disease and evaluate therapies, and these biomarkers may eventually be used as outcome measures in clinical trials. Biomarkers could be especially helpful to monitor changes during the time prior to diagnosis and appearance of overt symptomatology...
Researchers Develop Model For Better Testing, Targeting Of MPNST
Date: May-23-2013Researchers from the Masonic Cancer Center, University of Minnesota, and the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors (MPNST) that allow them to discover new genes and gene pathways driving this type of cancer. The research was published this week in the journal Nature Genetics. Utilizing the Sleeping Beauty transposon method, researchers in the lab of David Largaespada, Ph.D...
Minimizing Hair Loss Due To Cancer Radiation Therapy
Date: May-23-2013Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day. The study, which appears in the early online edition of the Proceedings of the National Academy of Sciences (PNAS), found that mice lost 85 percent of their hair if they received radiation therapy in the morning, compared to a 17 percent loss when treatment occurred in the evening...
Computer Model Predicts When Viruses Become Infectious
Date: May-23-2013A new computer model could help scientists predict when a particular strain of avian influenza might become infectious from bird to human, according to a report to be published in the International Journal Data Mining and Bioinformatics. Chuang Ma of the University of Arizona, Tucson, and colleagues at the Huazhong University of Science and Technology, Wuhan and the Wuhan Institute of Virology, explain that since 1997 several strains of avian influenza A virus (AIV), commonly known as "bird flu" have infected people directly from their natural bird hosts leading to numerous deaths...
Nationwide Study Maps Atherosclerotic Disease Heredity
Date: May-23-2013Researchers at Lund University in Sweden have mapped the significance of heredity for common forms of atherosclerotic disease. No studies have previously examined whether different forms of the disease share heredity. The study looked at coronary heart disease, ischemic stroke, peripheral arterial disease and atherosclerosis of the aorta in individuals whose siblings and parents have suffered different types of cardiovascular disease...
Video Game Players More Aggressive When Confronted By Human-Like Opponents
Date: May-23-2013Video games that pit players against human-looking characters may be more likely to provoke violent thoughts and words than games where monstrous creatures are the enemy, according to a new study by researchers at the University of Connecticut and Wake Forest University...
Improved Vaccine Delivery System
Date: May-23-2013A novel vaccine study from South Dakota State University (SDSU) headlined the groundbreaking research unveiled at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference (NBC). The meeting took place at the Sheraton San Diego Hotel and Marina. "The main goal of a vaccine is to stimulate the immune system to fight against a pathogen that causes the disease", explained Dr. Hemachand Tummala, assistant professor of Pharmaceutical Sciences at SDSU...
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