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What Affects Blood Pressure? Cell Phones, Salt And Yoga
Date: May-17-2013Presented at the 28th Annual Scientific Meeting of the American Society of Hypertension Considered the "silent killer," high blood pressure affects approximately one billion people worldwide, including one in three adults in the United States. From May 15 - 18, 2013, members of the medical community from across the globe gather at the 28th Annual Scientific Meeting of the American Society of Hypertension (ASH) in San Francisco to discuss the epidemic...
Women In 40s Continue To Get Routine Mammograms At Same Rate, Despite New Recommendations
Date: May-17-2013Women in their 40s continue to undergo routine breast cancer screenings despite national guidelines recommending otherwise, according to new Johns Hopkins research. In 2009, the U.S. Preventive Services Task Force (USPSTF) sifted through the evidence and recommended that while women ages 50-74 should continue to undergo mammograms every two years, those between the ages of 40 and 49 without a family history of breast cancer should discuss the risks and benefits of routine screening mammography with their physicians to make individual decisions...
Living Cells Must Use Their Brakes Moderately For Effective Speed Control
Date: May-17-2013How cells regulate their own function by "accelerating and braking" is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. In a study published by Nature Communications, researchers at Uppsala and Umea universities show a model of how cells' regulatory systems work. All living cells have a regulatory system similar to what can be found in today's smartphones...
Too Much Body Fat Makes Arteries Become Stiff After Middle Age
Date: May-17-2013In young people, blood vessels appear to be able to compensate for the effects of obesity. But after middle age, this adaptability is lost, and arteries become progressively stiffer as body fat rises - potentially increasing the risk of dying from cardiovascular disease. The researchers suggest that the harmful effects of body fat may be related to the total number of years that a person is overweight in adulthood. Further research is needed to find out when the effects of obesity lead to irreversible damage to the heart and arteries, they said...
Safeguarding Personal Privacy When Collecting DNA For Human Rights
Date: May-17-2013DNA databases might help identify victims of crime and human trafficking, but how do we safeguard the personal privacy of innocent victims and family members? A new report online in the Cell Press journal Trends in Genetics identifies a number of key challenges to consider as experts develop such programs. Identifying victims of human trafficking remains a challenge around the world; between 12 million and 27 million individuals are currently enslaved...
Hot On The TRAIL Of Graft Vs. Host Disease
Date: May-17-2013For patients with leukemia and other hematological malignancies, transplantation of hematopoietic stem cells (HSCT) can be a powerfully effective therapy. In addition to the desirable anti-tumor effect, transplanted cells can also attack the host tissue, resulting in graft-versus-host disease (GVHD). In this issue of the Journal of Clinical Investigation, Arnab Ghosh and colleagues at Memorial Sloan-Kettering Cancer Center found that expression of a protein that causes cell death, TRAIL, in transplanted cells was critical for an effective anti-tumor response...
Signals Identified That Direct The Immune System To Reject A Transplanted Organ
Date: May-17-2013Organ transplant rejection occurs when the transplant recipient's immune system identifies the transplanted organ as foreign tissue and attacks it. It was previously thought that T cells, the immune cells that mediate rejection, must first be activated by molecules known as chemokines in order to migrate to the transplanted organ. In this issue of the Journal of Clinical Investigation, Fadi Lakkis and colleagues at the University of Pittsburgh used mice to demonstrate that chemokine stimulation of T cells is not required for migration...
Data Addressing Patient And Physician Barriers To Clinical Trials To Be Presented By Experts
Date: May-17-2013Researchers from University Hospitals Case Medical Center's (UHCMC) Seidman Cancer Center in Cleveland, OH, will present findings from two studies evaluating new technologies designed to address common barriers to patient enrollment in clinical trials. Results from a large-scale, randomized trial demonstrated that the use of tailored, web-based videos delivering educational information to patients before an oncologist visit can significantly improve knowledge and reduce attitudinal barriers that impact enrollment in clinical trials...
Development Of Safer, More Environmentally Friendly Flame Retardants
Date: May-17-2013Amid concerns over the potential health effects of existing flame retardants for home furniture, fabrics and other material, scientists are reporting development of an "exceptionally" effective new retardant that appears safer and more environmentally friendly. Their report on the first-of-its-kind coating, ideal for the polyurethane foam in couches and bedding that causes many fire deaths, appears in ACS Macro Letters...
Relationship Between Sleep Duration And Suicidal Thoughts In People With Insomnia.
Date: May-17-2013Results of a new study show that every one-hour increase in sleep duration was associated with a 72 percent decrease in the likelihood of moderate or high suicide risk, in comparison with low risk. Data were adjusted for age, gender, race/ethnicity, education and age of onset of sleep difficulties. "We were surprised by the strength of the association between sleep duration and suicide risk," said primary author Linden Oliver, MA, clinical research coordinator for the University of Pennsylvania Behavioral Sleep Medicine Research Program in Philadelphia, Pa...
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