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Nanogel To Manage Type 1 Diabetes
Date: May-17-2013An extended insulin-release system comprising an injectable gel of nanoparticles may one day help patients with type 1 diabetes manage their condition without having constantly to test their blood-sugar and inject themselves with insulin. Designed at Massachusetts Institute of Technology (MIT) in the US, once in the body, the nanoparticles sense blood glucose concentration and automatically secrete the appropriate amount of insulin to keep it at the right level. Daniel Anderson, an associate professor of chemical engineering, leads the lab that designed the nanogel...
Robotic Kidney Transplants May Be Best Option For Obese Patients
Date: May-17-2013Obese patients who received robotic kidney transplants had fewer wound complications than patients who received traditional "open" transplant surgery, according to surgeons at the University of Illinois Hospital & Health Sciences System. The findings should allow more obese patients to receive kidney transplants. Patients with a body mass index (BMI) greater than 35 who have end-stage kidney disease are often denied transplantation, and patients with a BMI over 40 often die on dialysis without an opportunity for transplant...
Potential For Future Heart Disease Treatment Following Identification Of 4 Genes That Influence Levels Of 'Bad' Cholesterol
Date: May-17-2013Scientists at the Texas Biomedical Research Institute in San Antonio have identified four genes in baboons that influence levels of "bad" cholesterol. This discovery could lead to the development of new drugs to reduce the risk of heart disease. "Our findings are important because they provide new targets for the development of novel drugs to reduce heart disease risk in humans," said Laura Cox, Ph.D., a Texas Biomed geneticist...
New Ways Of Generating Stem Cells For Patients With Dysfunctional Or Damaged Tissues And Organs
Date: May-17-2013Somatic cell nuclear transfer (SCNT) is a technique in which the nucleus of a donor cell is transferred to an egg cell whose nucleus has been removed, generating embryos that are almost an identical genetic match to the donor individual. For the first time, a team of scientists has used SCNT to produce human embryonic stem cells (hESCs). This milestone, published by Cell Press in the journal Cell, opens up new avenues for using stem cells to understand patient-specific causes of disease and for developing personalized therapies...
Discovery Of H1N1 In Marine Mammals
Date: May-17-2013Scientists at the University of California, Davis, detected the H1N1 (2009) virus in free-ranging northern elephant seals off the central California coast a year after the human pandemic began, according to a study published in the journal PLOS ONE. It is the first report of that flu strain in any marine mammal. "We thought we might find influenza viruses, which have been found before in marine mammals, but we did not expect to find pandemic H1N1," said lead author Tracey Goldstein, an associate professor with the UC Davis One Health Institute and Wildlife Health Center...
Exercise Lowers Risk Of Lung And Colorectal Cancer Among Middle Aged Men
Date: May-17-2013New research conducted by researchers at the University of Vermont reveals that middle-aged men who engage in a lot of cardiovascular exercise are at a reduced risk of suffering from lung and colorectal cancer. In addition, those who exercise are less likely to die from prostate cancer (although their risk of contracting the disease remained the same)...
Active Videogaming May Improve Children's Health
Date: May-17-2013Exergaming (active videogaming) may provide an alternative type of exercise to prevent stationary behavior in children, a new study published in The Journal of Pediatrics claims. Obesity and physical inactivity levels in kids are significantly high - with less than 50% of primary school-aged boys and under 28% of girls reaching the minimum levels of exercise necessary to maintain proper health. Exergaming is using active console video games that track player movement to play the game, for example Xbox-Kinect, Wii...
Surveillance Best Follow-Up Strategy Among Men With Stage I Seminoma
Date: May-17-2013A long-term study of men with stage I seminoma, a common form of testicular cancer, suggests that surveillance for cancer recurrence, rather than additional chemotherapy or radiation therapy, is sufficient for the vast majority of patients who have undergone successful surgery for their cancer. In a new long-term study conducted in Denmark, researchers analyzed a national clinical database and found that 99.6% of patients who only underwent surveillance (following a successful surgery) were alive after 10 years of being diagnosed with testicular cancer...
Combination Drug Therapy May Be Best Treatment For Osteoporosis
Date: May-17-2013The combination of two different drugs for osteoporosis was found to increase bone mineral density (BMD) more than treatment with either drug alone, according to the results of a small clinical trial published in The Lancet. The combination, which included teriparatide, a bone-building (anabolic) drug, and denosumab, a targeted therapy to stop bone loss, also increased BMD better than previously reported with any available treatment in postmenopausal women with osteoporosis...
Molecular Profiling Timely For Tailoring Cancer Therapy
Date: May-17-2013A clinical trial has shown that patients, and their physicians, are eager to jump into next-era cancer care - analysis of an individual's tumor to find and target genetic mutations that drive the cancer. Results of the study, CUSTOM, are being presented at the 2013 annual meeting of the American Society of Clinical Oncology* years before investigators thought they would be ready. CUSTOM is the first completed prospective clinical trial that used genetic analysis alone to assign cancer treatment for patients with one of three different cancers...
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