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Identification Of Immune Cells That Suppress Genital Herpes Infections Has Implications For Vaccine Development

Date: May-10-2013
Fred Hutchinson Cancer Research Center and University of Washington scientists have identified a class of immune cells that reside long-term in the genital skin and mucosa and are believed to be responsible for suppressing recurring outbreaks of genital herpes. These immune cells also play a role in suppressing symptoms of genital herpes, which is why most sufferers of the disease are asymptomatic when viral reactivations occur...

Researchers Pinpoint Genetic Cause Of Sturge-Weber Syndrome And Port-Wine Stain Birthmarks

Date: May-10-2013
In new findings published in the New England Journal of Medicine (Epub ahead of print), researchers from the Kennedy Krieger Institute reveal the discovery of the cause - a genetic mutation that occurs before birth - of Sturge-Weber syndrome (SWS) and port-wine stain birthmarks. SWS is a rare disorder affecting approximately one in 20,000 births, while port-wine birthmarks are more common, affecting approximately one million individuals in the United States...

For Children With Common Conditions, Hospital Readmissions Affected By Nurse Staffing Ratios

Date: May-10-2013
A new study shows that pediatric nurse staffing ratios are significantly associated with hospital readmission for children with common medical and surgical conditions. The study, led by a nurse scientist at Cincinnati Children's Hospital Medical Center, is believed to be the first to examine the extent to which hospital nurse staffing levels are related to pediatric readmissions. Publication of the study comes just weeks after the introduction of federal legislation that would mandate nurse staffing ratios across the country...

Quality Of Life Better For Breast Cancer Patients Who Have Fun And Friends

Date: May-10-2013
Breast cancer patients who say they have people with whom they have a good time, or have "positive social interactions" with, are better able to deal with pain and other physical symptoms, according to a new Kaiser Permanente study published in Breast Cancer Research and Treatment. "This study provides research-based evidence that social support helps with physical symptoms," said lead author Candyce H. Kroenke, ScD, MPH, staff scientist with the Kaiser Permanente Division of Research. "Social support mechanisms matter in terms of physical outcomes...

Is There A Healthy Fast Food Option?

Date: May-10-2013
Subway may promote itself as the "healthy" fast food restaurant, but it might not be a much healthier alternative than McDonald's for adolescents, according to new UCLA research. In a study published in the Journal of Adolescent Health, the researchers found that adolescents who purchased Subway meals consumed nearly as many calories as they did at McDonald's. Meals from both restaurants are likely to contribute toward overeating and obesity, according to the researchers. "Every day, millions of people eat at McDonald's and Subway, the two largest fast food chains in the world," said Dr...

Results Improved For Those With Persistent Anorexia By Rethinking Treatment Goals

Date: May-10-2013
A new, multinational randomized clinical trial has found that patients with severe and enduring anorexia nervosa will not only stick with treatments but also make significant improvements with just a slight modification of the standard goals and methods of treatment. More than 85 percent of those who enrolled in the trial completed treatment - almost three times the usual retention rate. After eight months of outpatient treatment, patients in both treatment groups reported improved quality of life, reduced symptoms of mood disorders and enhanced social adjustment...

Transplanted Human Brain Cells Grow In Mice

Date: May-10-2013
A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat people with Parkinson's disease, epilepsy, and possibly even Alzheimer's disease, as well as complications of spinal cord injury such as chronic pain and spasticity...

During Formation Of Treatment-Resistant Colonies, 'Lucky' Bacteria Strike It Rich

Date: May-10-2013
In biology, we often think of natural selection and survival of the fittest. What about survival of the luckiest? Like pioneers in search of a better life, bacteria on a surface wander around and often organize into highly resilient communities, known as biofilms. It turns out that a lucky few bacteria become the elite cells that start the colonies, and they organize in a rich-get-richer pattern similar to the distribution of wealth in the U.S. economy, according to a new study by researchers at UCLA, Northwestern University and the University of Washington...

Brain Function Altered By Nerve Stimulation For Severe Depression

Date: May-10-2013
For nearly a decade, doctors have used an implanted electronic stimulator to treat severe depression in people who don't respond to standard antidepressant therapy. Now, preliminary brain scan studies conducted by researchers at Washington University School of Medicine in St. Louis are beginning to reveal the processes occurring in the brain during stimulation and may provide some clues about how the device improves depression. They found that vagus nerve stimulation brings about changes in brain metabolism weeks or even months before patients begin to feel better...

Scientists Bring Clarity To How Most Alzheimer's Drugs Sharpen Brain Performance

Date: May-10-2013
Scientists at the Virginia Tech Carilion Research Institute have discovered how the predominant class of Alzheimer's pharmaceuticals might sharpen the brain's performance One factor even more important than the size of a television screen is the quality of the signal it displays. Having a life-sized projection of Harry Potter dodging a Bludger in a Quidditch match is of little use if the details are lost to pixilation. The importance of transmitting clear signals, however, is not relegated to the airwaves. The same creed applies to the electrical impulses navigating a human brain...