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Multiple Sclerosis More Common In Black Women Than White
Date: May-07-2013Multiple sclerosis (MS) is more common in black women than in white women, according a new study. The research was conducted by Kaiser Permanente and was published in the journal Neurology. The results contradict the widely believed notion that black people are less vulnerable to the disease. The electronic health records of over 3.5 million members of Kaiser Permanente Southern California were analyzed from the beginning of 2008 to the end 2011. A total of 496 patients newly diagnosed with MS were identified...
The Energy Landscape Of Ion Channels Revealed By Computer Simulations
Date: May-07-2013Ion channels are important drug targets. A young team of researchers led by pharmacologist Anna Stary-Weinzinger from the Department of Pharmacology and Toxicology, University of Vienna investigated the opening and closing mechanisms of these channels: for the first time the full energy landscape of such a large protein ( 400 amino acids) could be calculated in atomic detail. The scientists identified a phenylalanine, which plays a key role for the transition between open and closed state...
Tanning Bed Risks - FDA Aims To Increase Consumer Awareness
Date: May-07-2013The U.S. Food and Drug Administration (FDA) wants to reclassify sunlamp products so that their labeling includes a recommendation against young people using them. For the moment, the FDA move is just a proposed order that it aims to eventually finalize. The American Academy of Dermatology informed that people who are exposed to ultraviolet radiation from indoor tanning have a 75% higher risk of developing the deadliest type of skin cancer - melanoma...
New Approach To Gene Sequencing Enables Rapid Identification Of Tick-Borne Lone Star Virus
Date: May-07-2013The tick-borne Lone Star virus has been conclusively identified as part of a family of other tick-borne viruses called bunyaviruses, which often cause fever, respiratory problems and bleeding, according to new research led by scientists at UC San Francisco (UCSF). What made the work especially promising, said principal investigator Charles Chiu, MD, PhD, was the speed at which the virus was definitively identified...
Valproate Migraine Drugs During Pregnancy Bad For Baby's IQ
Date: May-07-2013Using migraine prevention valproate sodium drugs during pregnancy can cause offspring to have a lower IQ, the US Food and Drug Administration (FDA) warned yesterday. Sodium valproate is an anticonvulsant prescribed by doctors for the treatment of migraine, bipolar disorder, PTSD (post-traumatic stress disorder), anxiety disorder, anorexia nervosa and epilepsy. The FDA is contraindicating valproate drugs for the prevention of migraine headaches for pregnant women. Contraindicated means it should never be used...
Warning By FDA Against High Dose Antidepressant Prescription May Be Unwarranted
Date: May-07-2013The U.S. Food and Drug Administration's warning that high doses of the antidepressant citalopram can cause potentially serious abnormal heart rhythms might be doing more harm than good. In 2011, the FDA attached a warning to the drug, also known as Celexa, based on data linking higher doses of the drug to potentially fatal abnormal changes in the electrical activity of the heart...
Gene Thought To Make Heart Tissues Turns Out To Make Blood And Muscles As Well
Date: May-07-2013New research out of the Lillehei Heart Institute at the University of Minnesota shows that by turning on just a single gene, Mesp1, different cell types including the heart, blood and muscle can be created from stem cells. The study was published in the journal Cell Stem Cell. "Previous research indicated that this gene was the "master regulator" for development of the heart, and that its activity prevented the differentiation of other cell types," said Michael Kyba, Ph.D...
Researchers Have Discovered Synthetic Agents Used To Treat HIV Inflammation
Date: May-07-2013HIV can cause serious inflammation, regardless of drug therapy, as it develops slowly in immune cells called macrophages. However, new research conducted at the Temple University School of Medicine's Department of Pathology and Laboratory Medicine and Center for Substance Abuse Research (CSAR) has just found that there are synthetic agents with anti-inflammatory properties, related to the active ingredient in cannabis, THC (tetrahydrocannabinol) which could limit and treat the chronic inflammation. According to new guidelines by the U.S...
How Environmental Stimuli And Brain Rhythms Generate Our Neuronal Maps Of The World
Date: May-07-2013Leaving the house in the morning may seem simple, but with every move we make, our brains are working feverishly to create maps of the outside world that allow us to navigate and to remember where we are. Take one step out the front door, and an individual brain cell fires. Pass by your rose bush on the way to the car, another specific neuron fires. And so it goes. Ultimately, the brain constructs its own pinpoint geographical chart that is far more precise than anything you'd find on Google Maps. But just how neurons make these maps of space has fascinated scientists for decades...
Researchers Discover New Target For Personalized Cancer Therapy
Date: May-07-2013A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a novel method to disrupt this growth signaling pathway, with findings that suggest a new treatment for breast, colon, melanoma and other cancers. The research team has pinpointed the cancer abnormality to a mutation in a gene called PIK3CA that results in a mutant protein, which may be an early cancer switch...
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