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Fundamental Discovery Reveals How The Properties Of Embryonic Stem Cells Are Controlled

Date: May-06-2013
The study, which focuses on the process by which these cells renew and increase in number, could help research to find new treatments. Researchers have found that a protein, which switches on genes to allow embryonic stem cells to self-renew, works better when the natural occurring level of the protein is reduced. It was previously thought that once levels of this protein - called Oct 4 - were reduced the numbers of new stem cells being produced would also fall...

In Sweden, Unethical Advertising Discovered At Launch Of Antidepressants

Date: May-06-2013
The new feature of the antidepressant drugs of the 1990s was that they had milder side-effects than their predecessors. Combined with aggressive marketing, this meant that annual sales in Sweden increased from just under EUR 18 million to over EUR 100 million in the space of just a few years. Most countries have an established system for self-regulation of pharmaceuticals advertising. Sweden has been held up internationally as a good example...

In Estrogen Receptor POS Breast Cancer, Genetic And Clinical Factors Best To Predict Late Recurrence

Date: May-06-2013
A new analysis has provided a comprehensive comparison of scores designed to predict which women with oestrogen-receptor positive breast cancer are at high risk of recurrence beyond five years after diagnosis, and may benefit from prolonged endocrine treatment. The promising new findings will likely benefit the many women with oestrogen-receptor positive breast cancer whose cancer recurs more than five years after diagnosis, researchers told the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium...

'Bionic' Ear Has Potential To Restore Or Enhance Human Hearing

Date: May-06-2013
Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability. The researchers' primary purpose was to explore an efficient and versatile means to merge electronics with tissue. The scientists used 3D printing of cells and nanoparticles followed by cell culture to combine a small coil antenna with cartilage, creating what they term a bionic ear...

Child Abuse Leaves Distinct Gene Activity Patterns

Date: May-06-2013
Abuse during childhood is different. A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, compared to adults with PTSD but without a history of child abuse. A team of researchers from Atlanta and Munich probed blood samples from 169 participants in the Grady Trauma Project, a study of more than 5000 Atlanta residents with high levels of exposure to violence, physical and sexual abuse and with high risk for civilian PTSD...

Scientists Pursue New Therapies As Deadly H7N9 Flu Spreads In China

Date: May-06-2013
An experimental drug has shown promise in treating influenza, preventing lung injury and death from the virus in preclinical studies, according to University of Maryland School of Medicine researchers publishing in the journal Nature. The scientists found that a drug called Eritoran can protect mice from death after they have been infected with a lethal dose of influenza virus. The potential value of this drug as single therapy or in combination with antivirals is further supported by previous research that found that it is safe for use in humans...

Twitter Analysis Reveals Abuse Of Adderall As College Study Aid

Date: May-06-2013
A growing number of college students are abusing the ADHD medication Adderall to give them an academic edge, and they're tweeting about it. Thanks to Twitter, tracking roughly when and where Adderall use happens is now possible. So a group of BYU health science and computer science researchers did just that. Their six-month study, appearing in the current issue of the Journal of Medical Internet Research, produced two major revelations about Adderall:   It is mentioned most heavily among students in the northeast and south regions of the U.S...

New Analysis Of The Contents Of Lipstick And Lip Gloss May Cause You To Pause Before Puckering

Date: May-06-2013
Researchers at the University of California, Berkeley's School of Public Health tested 32 different lipsticks and lip glosses commonly found in drugstores and department stores. They detected lead, cadmium, chromium, aluminum and five other metals, some of which were found at levels that could raise potential health concerns. Their findings were published online in the journal Environmental Health Perspectives...

The Magnitude Of Variation In Gene Expression Measurements Within Breast Cancers Revealed By Study

Date: May-06-2013
An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer. The results show, for the first time, which gene expression measurements may benefit from pooling of biopsies from a single tumour, researchers said at the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium. These findings represent an important step toward allowing doctors to more precisely tailor an individual's treatment to a detailed analysis of their tumour's gene expression...

Potential New Targeted Therapies For Breast Cancer

Date: May-06-2013
A study led by prominent breast cancer experts from Europe and the US has revealed a number of potentially important prospects for targeted therapies, and brings opportunities of truly personalised therapy for breast cancer a step closer, researchers said at the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium. The IMPAKT meeting presents cutting edge, 'translational' breast cancer research that is beginning to have an impact for patients...