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Peli1 Identified As Pivotal Actor In Animal Model Of Multiple Sclerosis
Date: May-06-2013Scientists have identified an influential link in a chain of events that leads to autoimmune inflammation of the central nervous system in a mouse model of multiple sclerosis (MS). An international team of researchers led by scientists in The University of Texas MD Anderson Cancer Center Department of Immunology reported their results in an advance online publication in Nature Medicine...
No Barrier To Predictive Testing Found In Breast Cancer Heterogeneity
Date: May-06-2013Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor cancer treatments to individual patients. The findings were reported at the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium. The IMPAKT meeting presents cutting edge, 'translational' breast cancer research that is beginning to have an impact for patients. In recent years it has become clear that breast cancers contain a variety of different cell types...
When A Child's Brain Under-Reacts To Pain In Others
Date: May-06-2013When children with conduct problems see images of others in pain, key parts of their brains don't react in the way they do in most people. This pattern of reduced brain activity upon witnessing pain may serve as a neurobiological risk factor for later adult psychopathy, say researchers who report their findings in the Cell Press journal Current Biology. That's not to say that all children with conduct problems are the same, or that all children showing this brain pattern in young life will become psychopaths...
Cervical Cancer Detection In Kenya Via Self-Collection Of Samples For HPV Testing
Date: May-06-2013In Kenya, women face a cervical cancer mortality rate that is approximately 10 times as high as in the United States. A study by researchers at the University of North Carolina at Chapel Hill suggests that training women to self-collect genital samples to test for human papillomavirus (HPV), the causative agent of cervical cancer, can increase the coverage rates of cervical cancer screening. Higher screening coverage helps increase rates of detection of cervical lesions and ultimately treatment of the disease...
Researchers Transform Adult Cells Into Early-Stage Nerve Cells, Bypassing The Pluripotent Stem Cell Stage
Date: May-06-2013A University of Wisconsin-Madison research group has converted skin cells from people and monkeys into a cell that can form a wide variety of nervous-system cells - without passing through the do-it-all stage called the induced pluripotent stem cell, or iPSC. Bypassing the ultra-flexible iPSC stage was a key advantage, says senior author Su-Chun Zhang, a professor of neuroscience and neurology. "IPSC cells can generate any cell type, which could be a problem for cell-based therapy to repair damage due to disease or injury in the nervous system...
Risk Factors For Heart Disease Likely Decrease Brain Function Too
Date: May-06-2013Brain function in adults as young as 35 may decline as their heart disease risk factors increase, according to new research in the American Heart Association journal Stroke. "Young adults may think the consequences of smoking or being overweight are years down the road, but they aren't," said Hanneke Joosten, M.D., lead author and nephrology fellow at the University Medical Center in Groningen, The Netherlands. "Most people know the negative effects of heart risk factors such as heart attack, stroke and renal impairment, but they do not realize it affects cognitive health...
Texting While Driving Common Among Teenagers
Date: May-06-2013Forty-three percent of teenagers say they text while driving, with males and older teens doing it more often than females and younger teenagers, Alexandra Bailin, from Cohen Children's Medical Center of New York explained in a presentation at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. yesterday. Bailin added that teenagers receive literally hundreds of text message each day. Unfortunately, there is one important message they are not getting - "Do not text and drive"...
How Form Of Complex Organs Evolves By Natural Selection: 3D Simulation
Date: May-06-2013Researchers at the Institute of Biotechnology at the Helsinki University and the Universitat Autonoma de Barcelona (UAB) have developed the first three-dimensional simulation of the evolution of morphology by integrating the mechanisms of genetic regulation that take place during embryo development. The study, published in Nature, highlights the real complexity of the genetic interactions that lead to adult organisms' phenotypes (physical forms), helps to explain how natural selection influences body form and leads towards much more realistic virtual experiments on evolution...
STD's Not Cancer Prevention Should Be The Focus For Promoting HPV Vaccine
Date: May-06-2013The HPV vaccine can prevent both cervical cancer and a nasty sexually transmitted disease in women. But emphasizing the STD prevention will persuade more young women to get the vaccine, a new study suggests. These results go against the conventional wisdom that scaring women about the possibility of cancer is the best way to get them vaccinated...
Botox Reveals New Wrinkle In Brain Communication
Date: May-06-2013National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel role for the molecules, called SNARES, may be a missing piece that scientists have been searching for to fully understand how brain cells communicate under normal and disease conditions. "The results were very surprising," said Ling-Gang Wu, Ph.D., a scientist at NIH's National Institute of Neurological Disorders and Stroke...
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