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UF Researchers Develop 'Nanotrain' For Targeted Cancer Drug Transport

Date: May-02-2013
University of Florida researchers have developed a "DNA nanotrain" that fast-tracks its payload of cancer-fighting drugs and bioimaging agents to tumor cells deep within the body. The nanotrain's ability to cost-effectively deliver high doses of drugs to precisely targeted cancers and other medical maladies without leaving behind toxic nano-clutter has been the elusive Holy Grail for scientists studying the teeny-tiny world of DNA nanotechnology...

Routine Prescribing Of Cinacalcet For End Stage Kidney Disease No Longer Warranted

Date: May-02-2013
Cinacalcet, a drug commonly given to patients with end stage kidney disease to help keep phosphorus and parathyroid blood levels within a target range and has few patient level clinical benefits and several adverse effects, suggesting that it should no longer be routinely prescribed, according to a study by international researchers published in this week's PLOS Medicine. These findings are important as cinacalcet has become the largest single drug cost for patients on dialysis in the US, with an annual expenditure of at least US $260 million...

Coaching Boys Into Men Program Proves Effective In Preventing Teen Dating Violence, Follow-Up Study Finds

Date: May-02-2013
Coaching Boys into Men (CBIM), a program that seeks to reduce dating violence and sexual assault, is proven effective to reduce abusive behaviors among male athletes toward their female partners, according to a study that will appear today in the online version of the American Journal of Preventive Medicine. The year-long evaluation study, led by Elizabeth Miller, M.D., Ph.D...

Emotional Effects Of Stroke 'As Devastating As Physical Effects' Says New Report

Date: May-02-2013
Too many stroke survivors and their families are abandoned when they leave hospital and left without the support they need to help them cope with the emotional impact of stroke. A new report published yesterday (Wednesday 1 May) by the Stroke Association reveals that the emotional impact of the condition can be as devastating as the physical effects. The charity's report, Feeling Overwhelmed, is based on the findings of a survey(i) of over 2,700 people affected by stroke...

C.difficile Vaccine Approach To Treatment Published In Expert Review Of Vaccines

Date: May-02-2013
Stellar Biotechnologies, Inc. ("Stellar" or "the Company") (OTCQB: SBOTF) (TSX-V: KLH), the world leader in sustainable manufacture of Keyhole Limpet Hemocyanin (KLH), today announced publication of a peer-reviewed article on Clostridium difficile ("C. difficile") in the current issue of Expert Review of Vaccines (April 2013, Vol. 12, No.4.). C. difficile is a potentially fatal intestinal superbug that is fast emerging as the most common hospital-based infection in the United States. Rates of C. difficile infection are at historic highs due to its resistance to common treatments...

UL Medical School Researchers Find Increased Death Risk In Patients Suffering From Gout And Elevated Uric Acid Levels

Date: May-02-2013
A new study led by researchers at the Graduate Entry Medical School (GEMS), University of Limerick (UL) has found that people suffering from gout and elevated serum uric acid have significantly increased risks of death. In their study, individuals with a diagnosis of gout experienced a 42 % higher risk of death from all causes and a 58% higher risk of cardiovascular death. The risks were greatest for individuals with the highest uric acid concentrations...

How We Decode 'Noisy' Language In Daily Life

Date: May-02-2013
Study: People use an array of strategies to make sense of confusing statements. Suppose you hear someone say, "The man gave the ice cream the child." Does that sentence seem plausible? Or do you assume it is missing a word? Such as: "The man gave the ice cream to the child." A new study by MIT researchers indicates that when we process language, we often make these kinds of mental edits. Moreover, it suggests that we seem to use specific strategies for making sense of confusing information -- the "noise" interfering with the signal conveyed in language, as researchers think of it...

Dogs Can Detect Breast And Lung Cancer Cells In Vitro

Date: May-02-2013
Researcher Hopes to Screen Smokers with Early Stage Lung Disease in Next Research Phase An internist and instructor at Ben-Gurion University of the Negev has conducted research proving that specially trained dogs can differentiate the smell of breast cancer cells from non-cancerous cells in cell cultures. The concept of using the sniffing ability of dogs to detect cancerous cells first emerged a decade ago in an article in a medical journal about a woman who discovered she had melanoma when her dog repeatedly barked at her tumor. Other individuals have reported similar experiences...

Microchip Proves Tightness Provokes Precocious Sperm Release

Date: May-02-2013
Sperm cell release can be triggered by tightening the grip around the delivery organ, according to a team of nano and microsystems engineers and plant biologists at the University of Montreal and Concordia University. Concordia's nanobiotech team devised a microchip that enabled the University of Montreal biologists to observe what happened when pollen tubes - the sperm delivery tools used by plants - tried to negotiate a microscopic obstacle course. The pollen tubes were exposed to a series of narrow, elastic openings resulting in a variety of cellular responses...

MR Brain Spectroscopy Detects Damage In The Hippocampus Of Patients Exposed To Excess Cortisol

Date: May-02-2013
New research shows that patients who are "biochemically cured" of Cushing's syndrome have levels of brain metabolites which are associated with neural damage. This will have implications for treatment of Cushing's patients, but might also suggest that patients using high levels of glucocorticoid drugs may suffer similar long-term problems. The work was presented yesterday at the European Congress of Endocrinology in Copenhagen. Cushing's syndrome is an endocrine disease causing an overproduction of the stress hormone cortisol...