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First Comprehensive Analysis Reveals Long-term Effectiveness Of SERMs For Preventing Breast Cancer
Date: May-02-2013Selective oestrogen receptor modulators (SERMs: tamoxifen, raloxifene, arzoxifene, and lasofoxifene) significantly reduce the risk of developing the most common type of breast cancer among women at both high and average risk of the disease* both during treatment, and for at least 5 years after stopping, according to the first comprehensive analysis of all SERM prevention trials to date published Online First in The Lancet...
Integrating Mental Health Services Around The World Is An Urgent Priority
Date: May-02-2013The first article in a landmark series to help health care workers and providers, donors, and decision makers understand the importance of including mental health care in global health programs is being published in this week's PLOS Medicine. Giving a global perspective on integrating mental health into health services around the world, the series focuses on mental, neurological, and substance use (MNS) disorders. Although these disorders account for an increasing burden of disease, affected people often lack access to mental health care in high-, middle-, and low-income countries...
New DNA Blood Test Could Increase Access To Herceptin
Date: May-02-2013A new blood test for women with breast cancer could identify more women who will benefit from the targeted treatment Herceptin without the need for uncomfortable biopsies. The new 'liquid biopsy' uses cutting-edge genetic techniques to detect breast cancer DNA in the bloodstream, and was developed by a team at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust...
Seaweed From North Atlantic Is Safe To Eat
Date: May-02-2013Seaweed has been eaten for thousands of years by people all over the world, and it can be considered a tasty and healthy food item. This is the conclusion from professor Ole G. Mouritsen, Department of Physics, Chemistry and Pharmacy at the University of Southern Denmark, who has scientifically studied the species dulse (Palmaria palmata). Dulse has traditionally been eaten by populations along North Atlantic coasts in countries such as Iceland, Ireland, England, Scotland, France, Norway and along the North American and Canadian Atlantic coasts...
Longer Sleep Duration Associated With Increased Risk Of Developing Colorectal Cancer
Date: May-02-2013A new study is the first to report a significant positive association between long sleep duration and the development of colorectal cancer, especially among individuals who are overweight or snore regularly. The results raise the possibility that obstructive sleep apnea may contribute to cancer risk...
Bile Diversion A Possible Alternative To Bariatric Weight Loss Surgery
Date: May-02-2013An experimental procedure successfully tested in obese laboratory rats may provide a less-invasive alternative to bariatric weight-loss surgery, researchers report online in Endocrinology. Scientists at Cincinnati Children's Hospital Medical Center used a catheter to re-direct the flow of bile from the bile duct into the small intestine, producing the same metabolic and weight-loss benefits as bariatric surgeries such as gastric by-pass. They named the procedure bile diversion, or BD...
In Adolescents, Intervention Can Prevent Postpartum Depression
Date: May-02-2013By targeting the factors that may play a significant role in the development of postpartum depression (PPD) in adolescent mothers, researchers at Women & Infants Hospital of Rhode Island believe they have found a way to prevent it. The team - led by Maureen G...
Emergency Physicians Advancing Emergency Care For Kids
Date: May-02-2013Most children with isolated skull fractures may not need to stay in the hospital, a finding which has the potential to save the health care system millions of dollars a year ("Isolated Skull Fractures: Trends in Management in U.S. Pediatric Emergency Departments"). In addition, a new device more accurately estimates children's weights, leading to more precise drug dosing in the ER ("Evaluation of the Mercy TAPE: Performance Against the Standard for Pediatric Weight Estimation")...
How T Cells Craft An Appropriate Immune Response
Date: May-02-2013A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature Immunology has identified a mechanism that helps T cells find that sweet spot where the strength of the immune response matches the threat. The finding offers important insight into the immune response...
Discovery Of Multiple Versions Of Microbial Defense Genes That Lend Themselves To Exploitation By Biotechnology
Date: May-02-2013Even bacteria have a kind of "immune system" they use to defend themselves against unwanted intruders - in their case, viruses. Scientists at the Helmholtz Center for Infection Research (HZI) in Braunschweig, Germany, were now able to show that this defense system is much more diverse than previously thought and that it comes in multiple versions. Their goal is to use the various newly discovered versions of the CRISPR-Cas gene for the targeted manipulation of genetic information, particularly for medical purposes...
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