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Study Shows How People Rationally Interpret Linguistic Input
Date: May-01-2013Suppose you hear someone say, "The man gave the ice cream the child." Does that sentence seem plausible? Or do you assume it is missing a word? Such as: "The man gave the ice cream to the child." A new study by MIT researchers indicates that when we process language, we often make these kinds of mental edits. Moreover, it suggests that we seem to use specific strategies for making sense of confusing information - the "noise" interfering with the signal conveyed in language, as researchers think of it...
Weigh Risks And Benefits Of Old And New Oral Anticoagulants
Date: May-01-2013NPS MedicineWise is urging health professionals to weigh the risks and benefits of oral anticoagulant therapies in people with non-valvular atrial fibulation (AF) following the Pharmaceutical Benefits Advisory Committee (PBAC) recommendation that newer oral anticoagulants (NOACs) be listed on the Pharmaceutical Benefits Scheme (PBS). Following an extensive review of NOACs over the past two years, PBAC has now recommended that dabigatran (Praxada), rivaroxaban (Xarelto), and apixaban (Eliquis) be subsidised under the scheme for stroke prevention in non-valvular AF...
Hydrogen Sulfide Reduces Joint Swelling
Date: May-01-2013A gas associated with the smell of rotten eggs has proven to effectively reduce joint swelling, in research which could lead to advances in the treatment of arthritis. Scientists at the University of Exeter Medical School have discovered that a novel drug molecule, which slowly generates the gas hydrogen sulfide (H2S), effectively reduces swelling and inflammation in arthritic joints. For years, H2S has been regarded as a highly poisonous by-product which is corrosive, flammable and explosive. But research is now showing an altogether more benign side to the substance...
Research May Lead To Self-Healing Or Biocompatible Materials That Mimic Human Tissues
Date: May-01-2013Squeeze a piece of silicone and it quickly returns to its original shape, as squishy as ever. But scientists at Rice University have discovered that the liquid crystal phase of silicone becomes 90 percent stiffer when silicone is gently and repeatedly compressed. Their research could lead to new strategies for self-healing materials or biocompatible materials that mimic human tissues. A paper on the research appeared in Nature's online journal Nature Communications...
Key Shift Identified In The Brain That Creates Drive To Overeat
Date: May-01-2013A team of American and Italian neuroscientists has identified a cellular change in the brain that accompanies obesity. The findings could explain the body's tendency to maintain undesirable weight levels, rather than an ideal weight, and identify possible targets for pharmacological efforts to address obesity. The findings, published in the Proceedings of the National Academy of Sciences Early Edition this week, identify a switch that occurs in neurons within the hypothalamus...
New Genetic Sequencing Lab Creates "Tipping Point" For Personalised Cancer Care In UK
Date: May-01-2013A new genetic profiling laboratory that will pioneer a quick and cost-effective new tumour test will give doctors a better chance of identifying the right treatment for UK cancer patients and increase access to clinical trials for the latest therapies. The London-based laboratory introduces new techniques that allow doctors to discover the gene alterations which drive cancer and to deliver these as diagnostic tests. This will allow doctors to better decide what treatment is most appropriate...
Oxford BioTherapeutics And Boehringer Ingelheim Enter Collaboration To Discover Novel Antibody Targets In Cancer
Date: May-01-2013Oxford BioTherapeutics (OBT) and Boehringer Ingelheim(BI) have announced a new alliance focused on the discovery of novel cancer antibody targets that OBT will identify with the help of its OGAP(R) discovery platform. Under the collaboration OBT will validate certain targets it has discovered that are compatible with targeting by various antibody drug formats across a range of cancer indications. Following completion of these activities, BI will have the exclusive right to develop and commercialize antibody products for selected programs...
Mapping Of Cancer Cell Fuel Pumps Paves The Way For New Drugs
Date: May-01-2013For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells. Since tumours are highly dependent on the transportation of nutrients in order to be able to grow rapidly, the researchers are hoping that the study published in the scientific magazine Nature Structural & Molecular Biology will form the basis for new strategies to fight cancer cells...
Transgene Presents Promising Pre-Clinical Data On TG1050 To Treat Chronic HBV At EASL 2013
Date: May-01-2013Initiation of a Phase I study in 2014. New first in class immunotherapeutic to treat CHB Transgene SA (Paris:TNG) (Euronext Paris: FR0005175080), a biopharmaceutical company that develops targeted immunotherapy products to treat major unmet medical needs in cancer and chronic infectious diseases, announced pre-clinical data obtained with its novel immunotherapeutic, TG1050, to treat chronic hepatitis B infection (CHB)...
EMS Not Used In One In Three Stroke Emergencies
Date: May-01-2013More than a third of stroke patients don't get to the hospital by ambulance, even though that's the fastest way to get there, according to new research in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal. Researchers studied records on more than 204,000 stroke patients arriving at emergency rooms at 1,563 hospitals participating in the American Heart Association/American Stroke Association's Get With The Guidelines®-Stroke quality improvement program in 2003-10. Emergency medical services (EMS) transported 63...
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