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Prognostic RNA Markers Identified In A Common Form Of Breast Cancer
Date: May-01-2013A Big-Data analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer. The study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) initially analyzed messenger RNA (mRNA) and microRNA expression, DNA methylation data and clinical findings for 466 patients with invasive ductal carcinoma, the most common type of breast cancer...
Experts Call For Medical Leaders To Establish Guidelines, Embed Honesty In Academic Cultures
Date: May-01-2013Unethical behavior among physicians-in-training threatens to erode public trust and confidence in the medical profession, say two academic physicians in the current issue of Mayo Clinic Proceedings. Reacting to CNN reports last year about the widespread use of "recalls" and "airplane notes" by radiology and dermatology residents, Gregory W. Ruhnke, MD, MS, MPH, of the Department of Medicine, University of Chicago, and David J...
Saxagliptin/Metformin Combination: Added Benefit Is Not Proven
Date: May-01-2013The fixed combination of the drugs saxagliptin and metformin (Komboglyze®) has been approved in Germany since November 2011 for the treatment of type 2 diabetes mellitus. In an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this fixed combination product offers an added benefit versus the current standard treatment. Such an added benefit cannot be derived from the dossier, however, as the manufacturer did not submit any relevant data...
400 IU Of Vitamin D Daily Is Sufficient For Infants
Date: May-01-2013Babies should be given a daily dose of vitamin D of 400 IU (international units) to help them stay healthy, according to a new study in JAMA. Vitamin D is important for the growth of healthy bones and to prevent rickets, and it is particularly crucial that infants get enough of it during their first year life because their bones are growing very quickly. For that reason, pediatricians often suggest that parents give babies a daily vitamin D supplement...
Breast Implants Can Hinder Breast Cancer Survival In Women
Date: May-01-2013Cosmetic breast implants may hinder survival in women who later develop breast cancer, according to a new small study published in BMJ. The authors suggest that these results be interpreted with caution because some of the twelve studies that were looked into did not adjust for a number of confounding elements. They emphasize the need for further studies into the long term health effects of breast implants...
Method Devised For Enhancing Chemical Exchange Saturation Transfer MRI
Date: May-01-2013Researchers at New York University and NYU Langone Medical Center have created a novel way to enhance MRI by reducing interference from large macromolecules that can often obscure images generated by current chemical exchange saturation transfer (CEST) methods. Their work, which appears in the Nature publishing group journal Scientific Reports, has the potential to improve MRI for cartilage as well as for brain tissue...
Researchers Successfully Treat Autism In Infants
Date: May-01-2013Most infants respond to a game of peek-a-boo with smiles at the very least, and, for those who find the activity particularly entertaining, gales of laughter. For infants with autism spectrum disorders (ASD), however, the game can be distressing rather than pleasant, and they'll do their best to tune out all aspects of it - and that includes the people playing with them. That disengagement is a hallmark of ASD, and one of the characteristics that amplifies the disorder as infants develop into children and then adults...
Bioengineers Create Rubber-Like Material Bearing Micropatterns For Stronger, More Elastic Hearts
Date: May-01-2013A team of bioengineers at Brigham and Women's Hospital (BWH) is the first to report creating artificial heart tissue that closely mimics the functions of natural heart tissue through the use of human-based materials. Their work will advance how clinicians treat the damaging effects caused by heart disease, the leading cause of death in the United States...
Molecular Role Of Gene Linked To Blood Vessel Formation Revealed
Date: May-01-2013University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly. Further study of this gene - a "transcription factor" called CASZ1 - may uncover a regulatory network that influences the development of cardiovascular disease. A number of other studies have already shown a genetic link between mutations in CASZ1 and hypertension...
Nurses Assess Robotic Assistants
Date: May-01-2013Roboticists are currently developing machines that have the potential to help patients with caregiving tasks, such as housework, feeding and walking. But before they reach the care recipients, assistive robots will first have to be accepted by healthcare providers such as nurses and nursing assistants. Based on a Georgia Institute of Technology study, it appears that they may be welcomed with open arms depending on the tasks at hand. More than half of healthcare providers interviewed said that if they were offered an assistant, they preferred it to be a robotic helper rather than a human...
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