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Toddlers' Aggressive Behavior May Be Predicted By Their Sweat Response In Infancy

Date: Apr-25-2013
Infants who sweat less in response to scary situations at age 1 show more physical and verbal aggression at age 3, according to new research published in Psychological Science, a journal of the Association for Psychological Science. Lower levels of sweat, as measured by skin conductance activity (SCA), have been linked with conduct disorder and aggressive behavior in children and adolescents...

New Pathway Identified That Enhances Tamoxifen To Tame Aggressive Breast Cancer

Date: Apr-25-2013
Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary activities so that it might work on more aggressive breast cancer. The research, published in the journal EMBO Molecular Medicine, is a promising development for women with basal-like breast cancer, sometimes known as triple-negative disease. This subtype has a poor prognosis because it is notoriously resistant to treatment...

Vesicular Stomatitis Virus Kills Melanoma In Animal Model, Spares Normal Cells

Date: Apr-25-2013
Researchers from Yale University School of Medicine have demonstrated that vesicular stomatitis virus (VSV) is highly competent at finding, infecting, and killing human melanoma cells, both in vitro and in animal models, while having little propensity to infect non-cancerous cells. "If it works as well in humans, this could confer a substantial benefit on patients afflicted with this deadly disease," says Anthony van den Pol, a researcher on the study. The research was published online ahead of print in the Journal of Virology...

3-D Motion Detection System Could Prevent Shoulder Injuries In Baseball Pitchers

Date: Apr-25-2013
A new 3-D motion detection system could help identify baseball pitchers who are at risk for shoulder injuries, according to a new study. The system can be used on the field and requires only a laptop computer. Other systems that evaluate pitchers' throwing motions require cameras and other equipment and generally are confined to indoor use. Loyola University Medical Center sports medicine surgeon Pietro Tonino, MD, is a co-author of the study, published in the journal Musculoskeletal Surgery...

Home Health-Care Visits Increase Hepatitis B Screening Rates For Hmong Americans

Date: Apr-25-2013
In the first study of its kind, lay health workers increased screening rates for hepatitis B virus (HBV) and knowledge about the disease among a group of Asian Americans, known as the Hmong, UC Davis researchers have found. The study appears online in Cancer Epidemiology, Biomarkers & Prevention. Hmong Americans, who originate from the mountainous areas of Laos, are at elevated risk for chronic hepatitis B - the major risk factor for liver cancer. They're also at greater risk than either white or other Asian Americans for poor outcomes from liver cancer...

Gardnerella Vaginalis May Contribute To Premature Births, STDs

Date: Apr-25-2013
New research at Washington University School of Medicine in St. Louis points to a common species of bacteria as an important contributor to bacterial vaginosis, a condition linked to preterm birth and increased risk of sexually transmitted diseases. The condition affects one in every three women, making it more common than yeast infections. But bacterial vaginosis often does not cause significant symptoms, leaving many women unaware they have it...

New Technologies Speed Health Care Delivery, Reduce Costs, Pioneer New Therapies

Date: Apr-25-2013
The current special issue of Technology and Innovation - Proceedings of the National Academy of Inventors®, devoted to studies on medical technology and health care delivery, focuses on a wide range of topics, from new technologies to reduce the cost of health care to understanding the human microbiome. "This special issue of Technology and Innovation on transformative health care technologies truly explores new frontiers where technology and health care cross," said Dr. Paul R...

Calorie Intake Reduced When Menu Labels Display Amount Of Exercise Needed To Burn Calories

Date: Apr-25-2013
More restaurants are displaying calorie information on their menus than ever before. It's not a coincidence; by law, retail food establishments that are part of a chain with twenty or more locations nationwide must disclose the calorie content of each menu item. The goal is to encourage consumers to make healthier, informed food choices. The majority of studies, however, show that providing information on calorie content does not lead to fewer calories ordered or consumed...

Study Suggests Increasing Complexity Of Gut Effect On Health

Date: Apr-25-2013
The microbiome is your body's set of microbial communities; microbial cells outnumber human cells roughly ten to one. Through studying the microbiome, scientists are learning more the relationship between these microbes and human health and disease. In looking at the effect of diet on the composition of the gut microbiome, Dr. Nanette Steinle of the University of Maryland's School of Medicine and Dr. Emmanuel Mongodin of the University of Maryland Institute of Genome Sciences wanted to determine if the Mediterranean diet would cause changes in an individual's microbiome...

The Role Of Epigenetic Influences In Autism

Date: Apr-25-2013
Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in Molecular Psychiatry, is the largest of its kind and may shed light on the biological mechanism by which environmental influences regulate the activity of certain genes and in turn contribute to the development of ASD and related behaviour traits...