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Stem Cell Senescence Found To Drive Aging

Date: Apr-22-2013
Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor or stem cells -- important for repair and regeneration of skeletal muscle and maintenance of healthy fat tissue -- are subject to cellular senescence, and that clearance of these cells limits age-related deterioration of these tissues. The findings appear online in the journal Cell Reports...

Half Of Americans Would Consider Donating A Kidney To A Stranger According To Poll

Date: Apr-22-2013
Good news for anyone needing a transplant; a new Mayo Clinic survey shows that the public's support for both living and deceased organ donation is increasing. Eighty-four percent of respondents said they would be very or somewhat likely to consider donating a kidney or a portion of their liver to a close friend or family member in need, and an astounding 49 percent said they would be very or somewhat likely to consider donating a kidney to someone they have never met, which is often referred to as altruistic or "Good Samaritan" kidney donation...

Research Team Uses Caffeine And Fruit Flies To Pinpoint Genetic Pathways That Guide DNA Repair In Cancer Cells

Date: Apr-22-2013
Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells - results that could one day be used to advance cancer therapies for people. Previous research has established that caffeine interferes with processes in cancer cells that control DNA repair, a finding that has generated interest in using the stimulant as a chemotherapy treatment...

Understanding The Teenage Brain

Date: Apr-22-2013
Teenagers are risk-takers - they're more likely than children or adults to experiment with illicit substances, have unprotected sex, and drive recklessly. But research shows that teenagers have the knowledge and ability to make competent decisions about risk, just like adults. So what explains their risky behavior? In a new report, psychological scientists Laurence Steinberg and Jason Chein of Temple University and Dustin Albert of Duke University argue that some teens' risky behavior reflects the unique effect of peer influence on the still-developing teenage brain...

Phase I Clinical Trial For An H5N1 Bird Flu Vaccine Shows Positive Results

Date: Apr-22-2013
IDRI (Infectious Disease Research Institute), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc. (TSX: MDG; OTCQX: MDCGF), a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today reported positive interim results from a Phase I clinical trial for an H5N1 Avian Influenza VLP vaccine candidate ("H5N1 vaccine")...

Interferon And Ribavirin Inhibit Coronavirus Replication In Cell Culture

Date: Apr-22-2013
National Institutes of Health (NIH) scientists studying an emerging coronavirus have found that a combination of two licensed antiviral drugs, ribavirin and interferon-alpha 2b, can stop the virus from replicating in laboratory-grown cells. These results suggest that the drug combination could be used to treat patients infected with the new coronavirus, but more research is needed to confirm this preliminary finding. The study appears in the journal Scientific Reports. The new coronavirus, called nCoV, was first identified in Saudi Arabia in September 2012...

Improving Emergency Radio Communications

Date: Apr-22-2013
Radio communications can be unreliable in underground tunnels and other large, complicated structures, posing a safety hazard for emergency responders. New tests of wireless emergency safety equipment by the National Institute of Standards and Technology (NIST) have defined the challenges more precisely and suggest how emergency communications might be improved...

When Standard Liver Cancer Treatment Doesn't Work Or Isn't Possible, New Ablation Technique Holds Promise

Date: Apr-21-2013
A new minimally invasive tumor ablation technique is providing hope for liver cancer patients who can't undergo surgery or thermal ablation, a study shows. The study of 22 patients at the Universitatsklinikum Regensberg in Regensberg, Germany, found that irreversible electroporation (IRE) successfully destroyed tumor tissue in 70% of these patients. These patients were not responsive to conventional therapy or their tumor was in a location that was not suitable for standard treatment, said Dr. Philipp Wiggermann, lead author of the study...

Promising New Noninvasive Test For Prostate Cancer Uses Laser Optics Plus Ultrasound Imaging

Date: Apr-21-2013
Multispectral photoacoustic imaging, which combines laser optics and ultrasound imaging technologies, can reliably distinguish between benign and malignant prostate tissue, a new study indicates. Researchers at the University of Rochester looked at 42 prostatectomy specimens using the new imaging technique. Multispectral photoacoustic imaging, still in its infancy, predicted 25 out of 26 benign tissues correctly and 13 out of 16 malignant tissues correctly, said Dr. Vikram Dogra, lead author of the study...

Link Studied Between Early Social Experiences And Adolescent Brain Function

Date: Apr-21-2013
Brains develop in the context of experience. Social experiences may be particularly relevant for developing neural circuits related to the experience of feeling or emotion. Factors such as negative life events and the quality of relationships may be especially influential. Adolescence is a key time to investigate how early social experiences contribute to brain development because it's a period of dramatic changes in brain function, brain structure, and social context, and it's when many psychiatric disorders first appear...