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Current Adult Generations Are Less Healthy Than Their Counterparts Of Previous Generations

Date: Apr-12-2013
Despite their greater life expectancy, the adults of today are less "metabolically" healthy than their counterparts of previous generations. That's the conclusion of a large cohort study from the Netherlands which compared generational shifts in a range of well established metabolic risk factors for cardiovascular disease. Assessing the trends, the investigators concluded that "the more recently born generations are doing worse", and warn "that the prevalence of metabolic risk factors and the lifelong exposure to them have increased and probably will continue to increase"...

Patients With Knee Osteoarthritis Benefit From 'Mobility Shoes'

Date: Apr-12-2013
New research suggests that patients with knee osteoarthritis (OA) who wear flat, flexible footwear (mobility shoes) had significant reduction in knee loading - the force placed upon the joint during daily activities. Results published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), show that long term use of the mobility shoes helped OA patients adapt their gait, or how they walk, which improved knee loading, even when the mobility shoes were no longer worn...

Federal Guidelines For Treating Teen Pelvic Inflammatory Disease Need Clarification

Date: Apr-12-2013
A Johns Hopkins Children's Center survey of 102 clinicians who treat teenage girls with pelvic inflammatory disease (PID) has found that official guidelines designed to inform decisions about hospitalization versus outpatient care leave some clinicians scratching their heads...

Huntington's, Alzheimer's And Parkinson's Patients May Benefit From Exciting Breakthrough By Scientists

Date: Apr-12-2013
A significant breakthrough has been made by scientists at The University of Manchester towards developing an effective treatment for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's. Researchers at the Manchester Institute of Biotechnology have detailed how an enzyme in the brain interacts with an exciting drug-like lead compound for Huntington's Disease to inhibit its activity. Their findings demonstrate that it can be developed as an effective treatment for neurodegenerative diseases. The research is published in the journal Nature...

Defining The Scope Of Skills For Family Medicine Residencies

Date: Apr-12-2013
Medical school graduates entering one family medicine residency program might receive training that is markedly different than another family medicine residency program. While these new medical school graduates, called residents, will gain the clinical knowledge needed to practice medicine, their scope of skills depend on their specific experiences as residents...

Positive Clinical Data Presented For Lead Accurin Candidate BIND-014 In Cancer Patients

Date: Apr-12-2013
BIND Therapeutics, a clinical-stage biopharmaceutical company developing a new class of highly selective targeted and programmable therapeutics called AccurinsTM, has announced that positive Phase 1 clinical data for BIND-014, the company's lead drug candidate, were presented in an oral presentation at the American Association for Cancer Research (AACR) 2013 Annual Meeting. Clinical investigators presented the Phase 1 results with BIND-014, its targeted docetaxel Accurin, in 28 heavily-pretreated patients with advanced or metastatic solid tumors...

When Different Providers Read Different Scans On Same Patient

Date: Apr-12-2013
According to a new study published online in the Journal of the American College of Radiology, any efficiencies in physician interpretation and diagnosis gained when different providers interpret different medical imaging scans performed on the same patient are minute and vary by procedure. Specifically, no potential intra-service work duplication was found when different exam interpretations were rendered by different physicians in the same group practice. Small potential efficiencies were found possible regarding pre- and post-service activities...

New Poll Ranks Chronic Pain Well Below Drug Addiction As A Major Health Problem

Date: Apr-12-2013
A new national public opinion poll commissioned by Research!America shows only 18% of respondents believe chronic pain is a major health problem, even though a majority of Americans (63%) say they know someone who experienced pain so severe that they sought prescription medicines to treat it. Chronic pain conditions affect about 100 million U.S. adults at a cost of approximately $600 billion annually in direct medical treatment costs and lost productivity. Most Americans are concerned about the misuse of pain medication to treat chronic pain...

Nuclear Medicine Imaging Technique Enables Study Of Awake, Unrestrained Mice

Date: Apr-12-2013
Setting a mouse free to roam might alarm most people, but not so for nuclear imaging researchers from the U.S. Department of Energy's Thomas Jefferson National Accelerator Facility, Oak Ridge National Laboratory, Johns Hopkins Medical School and the University of Maryland who have developed a new imaging system for mouse brain studies. Scientists use dynamic imaging of mice to follow changes in brain chemistry caused by the progression of disease or the application of a drug as an effective research tool for developing better ways to diagnose disease and formulate better treatments...

Stress During Gestation Leads To Obesity In Rat Model

Date: Apr-12-2013
The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated with the development of pathologies related with obesity. "The growing prevalence of obesity cannot be solely attributed to genetic factors or poor nutrition, but also to lifestyle and adverse environmental factors," as explained to SINC by Javier Campión, lead researcher of this new study...