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Treating Stable Coronary Artery Disease: Is Medical Therapy A Better And Safer Choice Than Angioplasty?
Date: Apr-12-2013The decision to perform an invasive procedure to open clogged arteries in the heart instead of first trying medication and lifestyle changes may not reduce a patient's risk of death or of a major cardiac event. Unnecessary procedures to treat chronic, stable heart disease contribute to rising health care costs. A targeted approach to avoiding this kind of overutilization by instead relying on evidence-based decision-making is presented in Population Health Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers...
Repetitive Transcranial Magnetic Stimulation For Focal Hand Dystonia Offers Short-Term Benefits
Date: Apr-12-2013Repetitive transcranial magnetic stimulation (rTMS) is being increasingly explored as a therapeutic tool for movement disorders associated with deficient inhibition throughout the central nervous system. This includes treatment of focal hand dystonia (FHD), characterized by involuntary movement of the fingers either curling into the palm or extending outward. A new study published in Restorative Neurology and Neuroscience reports short-term changes in behavioral, physiologic, and clinical measures that support further research into the therapeutic potential of rTMS...
Surrounding Yourself With Strong-Willed Friends May Increase Your Self-Control
Date: Apr-12-2013We all desire self-control - the resolve to skip happy hour and go to the gym instead, to finish a report before checking Facebook, to say no to the last piece of chocolate cake. Though many struggle to resist those temptations, new research suggests that people with low self-control prefer and depend on people with high self-control, possibly as a way to make up for the skills they themselves lack...
How Ozone Attacks Lipid Molecules That Line The Lung's Surface
Date: Apr-12-2013A research team from Birkbeck, University of London, Royal Holloway University and Uppsala University in Sweden, have helped explain how ozone causes severe respiratory problems and thousands of cases of premature death each year by attacking the fatty lining of our lungs. In a study published in Langmuir, the team used neutrons from the Institut Laue-Langevin in Grenoble and the UK's ISIS Neutron Source to observe how even a relatively low dose of ozone attacks lipid molecules that line the lung's surface...
Tiny Proteins Found To Prevent Bacterial Gene Transcription In The Search For New Antibiotics
Date: Apr-12-2013In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism. Now, scientists at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) in Saarbrücken, a branch of the Helmholtz Center for Infection Research (HZI), have published their findings and the implications for potential medical application in the scientific journal ACS Chemical Biology...
High Blood Pressure And Obesity Are No Longer Confined To Wealthy Countries: New Study
Date: Apr-12-2013These health risks have traditionally been associated with affluence, and in 1980, they were more prevalent in countries with a higher income. The new research, published in Circulation, shows that the average body mass index of the population is now just as high or higher in middle-income countries. For blood pressure, the situation has reversed among women, with a tendency for blood pressure to be higher in poorer countries...
Scientists Help Unravel The Central Mystery Of Alzheimer's Disease
Date: Apr-12-2013Scientists at The Scripps Research Institute (TSRI) have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it. The findings, reported in the journal Neuron, show that brain damage in Alzheimer's disease is linked to the overactivation of an enzyme called AMPK. When the scientists blocked this enzyme in mouse models of the disease, neurons were protected from loss of synapses - neuron-to-neuron connection points - typical of the early phase of Alzheimer's disease...
Fast Transcutaneous Non-Invasive Battery Recharger And Energy Feeder For Electronic Implants
Date: Apr-12-2013Antonio Abreu, a Sustainable Energy Systems PhD Student under the MIT Portugal Program, currently developing research work at LNEG (Laboratorio Nacional de Energia e Geologia I.P.) has developed a non-invasive battery recharger system for electronic implants that allows a longer life for the internal implantable devices in the human body such as, pacemakers, defibrillators, electric heart, delaying considerable the usual customary surgery intervention for replacement. According to the world health organization, cardiovascular diseases are the leading cause of deaths...
Drug Combination Of MK-1775 And Gemcitabine More Effective In Treating Sarcomas
Date: Apr-12-2013Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report that the drug combination of MK-1775 and gemcitabine resulted in a 70 percent decrease in the tumor volume when compared to receiving one drug or the other. Their study was published in the online edition of PLOS ONE...
Discovery Of Key Pathway To Stop Dangerous, Out-Of-Control Inflammation
Date: Apr-12-2013A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues. Jian-Dong Li, director of Georgia State's Center for Inflammation, Immunity and Infection, and his team discovered that blocking a certain pathway involved in the biological process of inflammation will suppress it. Inhibiting a molecule called phosphodiesterase 4B, or PDE4B, suppresses inflammation by affecting a key gene called CLYD, a gene that serves as a brake on inflammation...
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